Results 11 to 20 of about 68,495 (293)
, 2011 Many reviews of the cerebral cortex use information derived from primates, carnivores, rodents, and other species, focusing on common traits to synthesize a general description of the mammalian cortex.
Matthew Kirkcaldie (14741308)
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Embryonic regionalization of the neocortex
Mechanisms of Development, 2001 Understanding the development of the vertebrate brain and in particular that of the neocortex, where high brain functions reside, remains one of the most difficult and exciting tasks in biology. In this review, we discuss recent experimental evidence as well as different possibilities for the intrinsic regionalization of the embryonic dorsal ...
Ruiz Altaba, Ariel +2 more
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Frontiers in Cell and Developmental Biology, 2020 Neural progenitor cells (NPCs) play a central role during the development and evolution of the mammalian neocortex. Precise temporal and spatial control of NPC proliferation by a concert of cell-intrinsic and cell-extrinsic factors is essential for the ...
Lei Xing, Wieland B. Huttner
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Adaptive Network Stabilization Despite Profound Structural Reorganization in Human Organotypic Cultures. [PDF]
Adv Sci (Weinh)Adult human organotypic cortical slices undergo marked neuronal loss, laminar disruption, and glial activation, yet their network activity progressively stabilizes after a variable period. Electrophysiology, longitudinal calcium imaging, and quantitative histology show that structurally remodeled human circuits show adaptive capacity resulting in ...
Tóth EZ +20 more
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The EMBO JournalNeocortex expansion during evolution is linked to higher numbers of neurons, which are thought to result from increased proliferative capacity and neurogenic potential of basal progenitor cells during development.
Paula Cubillos +14 more
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Spread of epileptiform activity in the immature rat neocortex studied with voltage-sensitive dyes and laser scanning microscopy [PDF]
, 1994 1. Adult rats and rats with a postnatal age of 3-29 days (PN 3-29) were used for the preparation of in vitro slices of the frontal neocortex. Epileptiform activity was induced by bath application of the gamma-aminobutyric acid-A (GABAA) receptor ...
Rucker, F. +3 more
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Evolution of the neocortex [PDF]
Current Biology, 2006 Humans have exceptional skills and abilities that largely depend on their brains. One of the major questions of modern neuroscience is to understand how the human brain evolved. In general, we share brain features and functions with other animals in proportion to how closely we are related to them.
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Frontiers in Neural Circuits, 2019 There exist two major types of striatum-targeting neocortical neurons, specifically, intratelencephalic (IT) neurons and pyramidal-tract (PT) neurons. Regarding their striatal projections, it was once suggested that IT axons are extended whereas PT axons
Kenji Morita +5 more
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Subplate Neurons as an Organizer of Mammalian Neocortical Development
Frontiers in Neuroanatomy, 2020 Subplate neurons (SpNs) are one of the earliest born and matured neurons in the developing cerebral cortex and play an important role in the early development of the neocortex.
Chiaki Ohtaka-Maruyama
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in mice leads to neocortex expansion and increased memory flexibility
, 2021 Neocortex expansion during human evolution provides a basis for our enhanced cognitive abilities. Yet, which genes implicated in neocortex expansion are actually responsible for higher cognitive abilities is unknown.
Pinson, A. +26 more
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