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Memory Engrams in the Neocortex

The Neuroscientist, 2020
While in the past much of our knowledge about memory representations in the brain has relied on loss-of-function studies in which whole brain regions were temporarily inactivated or permanently lesioned, the recent development of new methods has ushered in a new era of downright “engram excitement.” Animal research is now able to specifically label ...
Svenja Brodt, Steffen Gais
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The Neocortex of the Dog

Anatomia, Histologia, Embryologia, 1988
SummaryThis article presents abundant rigorous information concerning the whole of the neocortex of a gyrencephalate mammal (the dog), including the buried cortex. The outline of 50 μm transverse sections stained with cresyl echt violet were measured with a Vids II image analyser, measurements being taken between reference points which mostly consisted
I, Salazar   +4 more
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Embryonic regionalization of the neocortex

open access: yesMechanisms of Development, 2001
Understanding the development of the vertebrate brain and in particular that of the neocortex, where high brain functions reside, remains one of the most difficult and exciting tasks in biology. In this review, we discuss recent experimental evidence as well as different possibilities for the intrinsic regionalization of the embryonic dorsal ...
Yorick Gitton, , Ariel Ruiz I Altaba
exaly   +4 more sources

Microcircuitry of the Neocortex

2017
The neocortex is a sheet of neurons organized into six layers, each receiving and projecting to specific brain areas depending on the neocortical region. This neuronal sheet, with some exceptions, displays very little horizontal and anatomical segregation, but it is dynamically segregated into functional modules during stimulation. Excitatory pyramidal
Ramaswamy, Srikanth   +3 more
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The Neocortex

2019
Experts review the latest research on the neocortex and consider potential directions for future research. Over the past decade, technological advances have dramatically increased information on the structural and functional organization of the brain, especially the cerebral cortex.
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Development of isolated neocortex

Experientia, 1973
La migration des neuroblastes et la croissance des aires dendritiques de base des neurones pyramidaux font ici l'objet d'une etude portant sur les regions IV et Vb du neocortex cerebral isole de rats de souche Wistar. La migration des neuroblastes s'effectuait normalement et aboutissait au dispositif habituel ordonne en 6 regions.
M, Berry, T, Hollingworth
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Interlaminar Connections in the Neocortex

Cerebral Cortex, 2003
This review summarizes the local circuit, interlaminar connections in adult mammalian neocortex. These were first demonstrated with anatomical techniques, which indicate some of the exquisite spatial precision present in the circuitry. Details, such as the class(es) of neurons targeted by some of these projections, have begun to be added in studies ...
Alex M, Thomson, A Peter, Bannister
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A Canonical Microcircuit for Neocortex

Neural Computation, 1989
We have used microanatomy derived from single neurons, and in vivo intracellular recordings to develop a simplified circuit of the visual cortex. The circuit explains the intracellular responses to pulse stimulation in terms of the interactions between three basic populations of neurons, and reveals the following features of cortical processing that ...
Rodney J. Douglas   +2 more
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Aging and the human neocortex

Experimental Gerontology, 2003
Neurostereology has been applied to quantitative anatomical study of the human brain. Such studies have included the total neocortical number of neurons and glial cells, the estimated size distribution of neocortical neurons, the total myelinated fiber length in the brain white matter, the total number of synapses in the neocortex, and the effect of ...
Bente, Pakkenberg   +6 more
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