Results 141 to 150 of about 2,140 (214)
Glia, Volume 74, Issue 9, September 2026.Dual‐color STORM resolves the precise architecture and protein distributions within hippocampal astrocytes at the nanoscale. Identification of a sparse but specific MAGL pool in CA1 astrocytic processes. Astrocytic MAGL is not synapse‐associated, suggesting a synapse‐independent role.
Miklós Zöldi, István Katona
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Dorso‐Ventral and Night‐Day Regulation of Extracellular K+ Dynamics in Mouse Hippocampal Astrocytes
Glia, Volume 74, Issue 9, September 2026.Hippocampal astrocytic K+ buffering varies by region and time. Ventral astrocytes show faster K+ accumulation due to reduced Kir4.1 function. Such regional divergence is modulated by circadian shifts in Kir4.1 and gap junction coupling. ABSTRACT Astrocytes regulate extracellular potassium (K+) through multiple mechanisms operating across distinct ...
Nariman Kiani +5 more
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Deletion of Astrocytic TNFR1 Attenuates Hyperexcitability and Initiation of Epileptogenesis
Glia, Volume 74, Issue 9, September 2026.Inducible, astrocyte‐specific deletion of TNFR1 reduces basal EEG spectral power. Loss of astrocytic TNFR1 attenuates acute seizure activity in two distinct experimental models of epilepsy. Deletion of TNFR1 in astrocytes limits epilepsy development and hippocampal pathology in a mouse model of temporal lobe epilepsy with hippocampal sclerosis ...
Lukas Henning +6 more
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Brain Pathology, Volume 36, Issue 5, September 2026.Neuritic plaques increase in the intermediate stage of Alzheimer's neuropathological change. The intermediate stage of Alzheimer's disease was investigated by transcriptomics and immunohistochemistry. This revealed that inflammasome sensors NLRP1, NLRP3, and AIM2 oligomerize with ASC speck to form the inflammasome complex and initiate the downstream ...
Juan Pablo de Rivero Vaccari +10 more
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Neuromorphic Denoising with Fully Analog Memristive In‐Memory Computing
Advanced Intelligent Systems, Volume 8, Issue 8, August 2026.This article borrows the concepts of episodic memory in human brains to experimentally implement a memristor‐based neuromorphic denoising process. A homogeneous memristor processing unit is experimentally demonstrated for both temporal storage and neural network computation, imitating the synapses in the human brain.
Daijing Shi +5 more
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Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.Abstract INTRODUCTION We examined whether locus coeruleus (LC) contrast, an indirect proxy for neuronal density and structural health, was related to delayed episodic memory in healthy older adults (OAs) and those with mild cognitive impairment (MCI) and its association with encoding‐related brain activity, controlling for emotional salience.
Lucia Penalba‐Sánchez +12 more
wiley +1 more source
Integrative regulation of cerebral blood flow in response to exercise and environmental extremes
Experimental Physiology, EarlyView.
Shigehiko Ogoh, Damian M. Bailey
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Classification of tau status with machine learning models in amyloid‐positive cohorts
Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.Abstract INTRODUCTION Although tau positron emission tomography (PET) imaging is effective for staging tau pathology, it is limited clinically by cost and availability. Machine learning models based on magnetic resonance imaging (MRI)– and amyloid PET–derived features may serve as useful screening tools for tau pathology.
Yun‐Chi Lin +4 more
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Sex specificity of resistance to caTAUstrophe
Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.Abstract INTRODUCTION As amyloid beta (Aβ) accumulates, tau pathology spreads beyond medial temporal lobe (MTL) into neocortical (NEO) regions, though some older adults resist this progression, or what we call here “caTAUstrophe.” Given previous evidence of higher tau levels in women, we tested how tau resistance presented in men and women separately ...
Maria Carrigan +21 more
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Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.Abstract INTRODUCTION Alzheimer's disease neuropathologic change (ADNC) and limbic‐predominant age‐related transactive response DNA‐binding protein 43 kDa (TDP‐43) encephalopathy neuropathologic change (LATENC) are common in older adults, yet differences in brain morphometry patterns when one or both pathologies are present remain unclear.
Khalid Saifullah +7 more
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