Results 11 to 20 of about 115,708 (268)

Genetic manipulation of reptilian embryos: toward an understanding of cortical development and evolution

open access: yesFrontiers in Neuroscience, 2015
The mammalian neocortex is a remarkable structure that is characterized by tangential surface expansion and six-layered lamination. However, how the mammalian neocortex emerged during evolution remains elusive.
Tadashi eNomura   +4 more
doaj   +1 more source

Synaptic Plasticity in Cortical Inhibitory Neurons: What Mechanisms May Help to Balance Synaptic Weight Changes?

open access: yesFrontiers in Cellular Neuroscience, 2020
Inhibitory neurons play a fundamental role in the normal operation of neuronal networks. Diverse types of inhibitory neurons serve vital functions in cortical networks, such as balancing excitation and taming excessive activity, organizing neuronal ...
Nicholas M. Bannon   +2 more
doaj   +1 more source

Differential Striatal Axonal Arborizations of the Intratelencephalic and Pyramidal-Tract Neurons: Analysis of the Data in the MouseLight Database

open access: yesFrontiers in Neural Circuits, 2019
There exist two major types of striatum-targeting neocortical neurons, specifically, intratelencephalic (IT) neurons and pyramidal-tract (PT) neurons. Regarding their striatal projections, it was once suggested that IT axons are extended whereas PT axons
Kenji Morita   +5 more
doaj   +1 more source

Subplate Neurons as an Organizer of Mammalian Neocortical Development

open access: yesFrontiers in Neuroanatomy, 2020
Subplate neurons (SpNs) are one of the earliest born and matured neurons in the developing cerebral cortex and play an important role in the early development of the neocortex.
Chiaki Ohtaka-Maruyama
doaj   +1 more source

Effects of neonatal dexamethasone and CpdA on the expression of genes for apoptosis regulator proteins in the neonatal hippocampus

open access: yesИнтегративная физиология, 2021
Glucocorticoids (GC) are crucial regulators of homeostasis and function. Despite its negative side effects, glucocorticoid therapy in neonates is widely used antenatally for accelerating fetal lung maturation in cases of preterm birth.
Дмитрий Александрович Ланшаков   +4 more
doaj   +1 more source

TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death [PDF]

open access: yes, 1997
Newborn mice carrying targeted mutations in genes encoding neurotrophins or their signaling Trk receptors display severe neuronal deficits in the peripheral nervous system but not in the CNS. In this study, we show that trkB (¿/¿) mice have a significant
Alcántara Horrillo, Soledad   +5 more
core   +1 more source

The role of thyroid hormones in regulating of fatty acid spectrum of brain lipids: ontogenetic aspect.

open access: yesMedičnì Perspektivi, 2016
In experiments on rats of three age groups the role of thyroid hormones in the regulation of fatty acid spectrum of cortical and hippocampus lipids was studied.
A. G. Rodynskiy   +2 more
doaj   +1 more source

An Attempt at a Unified Theory of the Neocortical Microcircuit in Sensory Cortex

open access: yesFrontiers in Neural Circuits, 2020
The neocortex performs a wide range of functions, including working memory, sensory perception, and motor planning. Despite this diversity in function, evidence suggests that the neocortex is made up of repeating subunits (“macrocolumns”), each of which ...
Max Bennett
doaj   +1 more source

Dynamical Mean Field approximation of a canonical cortical model for studying inter-population synchrony [PDF]

open access: yes, 2011
The goal of this paper is twofold. We propose and explore a model to study the synchronization among populations in the canonical model of the neocortex proposed previously by (R.J. Douglas, K.A.C. Martin, A functional microcircuit for cat visual cortex.
Ramó, Roberto Carlos Sotero Diaz
core   +2 more sources

Increased expression of matrix metalloproteinase-9 in patients with temporal lobe epilepsy [PDF]

open access: yes, 2014
Aim: The molecular mechanism of epileptogenesis in temporal lobe epilepsy is still unclear. Experimental studies have suggested that matrix metalloproteinases have important roles in this process, but human studies are limited.
Acar, Feridun   +3 more
core   +1 more source

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