Results 91 to 100 of about 2,682,293 (230)

Localizing value of ecstatic phenomenon in epilepsy surgery: A systematic review

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective A systematic review was conducted to synthesize current anatomo‐clinical correlations of ecstatic symptoms in focal epilepsy, aiming to provide evidence‐based guidance for interpreting this ictal semiology during presurgical evaluation.
Mihai Dragos Maliia   +2 more
wiley   +1 more source

How human-specific genes have expanded the primate neocortex:

open access: yes, 2023
In den letzten Jahren zeigte sich, dass menschenspezifische Gene einen entscheidenden Beitrag zu der evolutionären Neokortex-Expansion des Menschen leisteten. Eines dieser Gene ist ARHGAP11B.
Heide, Michael, Huttner, Wieland B.
core   +1 more source

Translocator protein positron emission tomography as a biomarker for posttraumatic epilepsy and behavioral comorbidities following traumatic brain injury

open access: yesEpilepsia, EarlyView.
Abstract Objective Traumatic brain injury (TBI) induces widespread and persistent neuroinflammation, which is increasingly recognized as a key contributor to chronic sequelae including posttraumatic epilepsy (PTE), cognitive deficits, and neuropsychiatric disturbances. However, reliable biomarkers for identifying individuals at risk for these long‐term
Mohit Javalgekar   +14 more
wiley   +1 more source

TULP4, a novel E3 ligase gene, participates in neuronal migration as a candidate in schizophrenia

open access: yesCNS Neuroscience &Therapeutics, EarlyView., 2023
Mutations identified from four SCZ pedigrees resulted in decreased TULP4 expression. Tulp4 knockdown caused delayed neuron migration in embryonic mice, and impaired cognition and prepulse inhibition in adult mice. These phenotypes may be related to TULP4 through its involvement in the formation of a novel E3 ubiquitin ligases.
Yan Bi   +19 more
wiley   +1 more source

Pianno: a probabilistic framework automating semantic annotation for spatial transcriptomics

open access: yesNature Communications
Spatial transcriptomics has revolutionized the study of gene expression within tissues, while preserving spatial context. However, annotating spatial spots’ biological identity remains a challenge.
Yuqiu Zhou   +3 more
doaj   +1 more source

Perils and progress in epilepsy surgery utilization: Twenty‐five years later

open access: yesEpilepsia, EarlyView.
Abstract More than 25 years have passed since the first randomized controlled trial (RCT) established that surgery is superior to continued anti‐seizure medication (ASM) for drug‐resistant temporal lobe epilepsy, and nearly as long since a joint practice parameter urged that appropriate surgical candidates be referred to a specialized center for ...
Dario J. Englot
wiley   +1 more source

Early treatment prevents neuronal loss in experimental status epilepticus: A magnetic resonance spectroscopic imaging study

open access: yesEpilepsia, EarlyView.
Abstract Objective In status epilepticus there are concerns that the prolonged high‐intensity electrographic seizure activity causes neuronal death and poorer outcomes. In animal models of status epilepticus, early treatment that stops the seizures prevents the later development of epilepsy.
Yue Chen   +2 more
wiley   +1 more source

Relative neocortex size and its correlates in dolphins : comparisons with humans and implications for mental evolution. [PDF]

open access: yes, 1998
Thesis (Ph.D.)-University of Natal, Pietermaritzburg, 1998.The superior neocortex ratios in primates and their distinctive relationship with sociality among terrestrial mammals are well documented.
Tschudin, Alain Jean-Paul Charles.
core   +1 more source

Multiple Origins of Neocortex: Contributions of the Dorsal Ventricular Ridge

open access: yes, 1991
The uniqueness of mammalian neocortex may ultimately only be clarified with improved understanding of the evolutionary origins of cortical structure and cortical functions.
Harvey J. Karten   +3 more
core   +1 more source

Automated segmentation of postsurgical resection cavities on magnetic resonance imaging in focal epilepsy: A Multicentre Epilepsy Lesion Detection study

open access: yesEpilepsia, EarlyView.
Abstract Objective Quantitative assessment of extent of tissue resection following epilepsy surgery requires accurate delineation of the resection cavity on postoperative magnetic resonance imaging (MRI). Current methods for resection cavity masking are time‐consuming and labor‐intensive, and existing automated approaches exhibit variable segmentation ...
Jieun Seo   +91 more
wiley   +1 more source

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