Results 41 to 50 of about 178,038 (303)
Sequestration of noble gases in giant planet interiors
The Galileo probe showed that Jupiter's atmosphere is severely depleted in neon compared to protosolar values. We show, via ab initio simulations of the partitioning of neon between hydrogen and helium phases, that the observed depletion can be explained
Burkhard Militzer +2 more
core +1 more source
The contribution of Oxygen-Neon white dwarfs to the MACHO content of the Galactic Halo [PDF]
The interpretation of microlensing results towards the Large Magellanic Cloud (LMC) still remains controversial. White dwarfs have been proposed to explain these results and, hence, to contribute significantly to the mass budget of our Galaxy. However,
Adams +45 more
core +4 more sources
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Electronic spectra of linear HC$_5$H and cumulene carbene H$_2$C$_5$ [PDF]
The $1 ^3\Sigma_u^- \leftarrow X^3\Sigma_g^-$ transition of linear HC$_5$H (A) has been observed in a neon matrix and gas phase. The assignment is based on mass-selective experiments, extrapolation of previous results of the longer HC$_{2n+1}$H ...
Adam Nagy +7 more
core +2 more sources
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
ON THE CHANGE OF THE SURFACE ENERGY UNDER THE ALL-ROUND COMPRESSION OR SPRAINING OF THE CRYSTAL [PDF]
Expressions for the dependencies of the specific surface energy σ and its isochoric derivative with respect to the temperature (∂σ/∂T)V versus of the relative volume V/V0 of the simple matter crystal are received.
M.N. Magomedov
doaj
The Global Ecosystem Dynamics Investigation (GEDI), a new spaceborne LiDAR system of the National Aeronautics and Space Administration (NASA), has the potential to revolutionize global measurements of vertical vegetation structure.
Cangjiao Wang +7 more
doaj +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

