Results 101 to 110 of about 19,143 (231)

Fc-empowered exosomes with superior epithelial layer transmission and lung distribution ability for pulmonary vaccination

Bioactive Materials
Mucosal vaccines offer potential benefits over parenteral vaccines for they can trigger both systemic immune protection and immune responses at the predominant sites of pathogen infection.
Fan Meng, Haonan Xing, Jingru Li, Yingqi Liu, Li Tang, Zehong Chen, Xiran Jia, Zenglin Yin, Jing Yi, Mei Lu, Xiuli Gao, Aiping Zheng   +11 more
doaj   +1 more source

The therapeutic age of the neonatal Fc receptor. [PDF]

Nat Rev Immunol, 2023
Pyzik M, Kozicky LK, Gandhi AK, Blumberg RS.   +3 more
europepmc   +1 more source

Binding of subclasses of rat immunoglobulin G to detergent-isolated Fc receptor from neonatal rat intestine.

, 1987
Steve Hobbs, L. Elizabeth Jackson, Jane Peppard   +2 more
openalex   +1 more source

Matrix Stiffness Promotes DRP1‐Mediated Myofibroblast Senescence to Drive Silica‐Induced Pulmonary Fibrosis

Aging Cell, EarlyView.
These findings identify matrix stiffness‐driven cellular senescence as a critical mechanism in silicosis progression, providing a rationale for targeting senescent cells as an antifibrotic therapeutic strategy. ABSTRACT Silicosis is an occupational lung disease characterized by diffuse pulmonary fibrosis resulting from inhalation of silica particles ...
Xinying Zeng, Jingya Li, Jiaxin Wang, Jiaxin Zhang, Yuhua Wang, Yan Wang, Yifei Wang, Lin Tian, Zhonghui Zhu   +8 more
wiley   +1 more source

Transport of antibody into the skin is only partially dependent upon the neonatal Fc-receptor. [PDF]

PLoS One, 2023
Nasir G, Sinnis P.
europepmc   +1 more source

Efficiency of immunoglobulin G replacement therapy in common variable immunodeficiency: correlations with clinical phenotype and polymorphism of the neonatal Fc receptor

, 2012
Valérie Gouilleux‐Gruart, Helen Chapel, Sylvie Chevret, Mary Lucas, Marion Malphettes, Claire Fieschi, Smita Y. Patel, David Boutboul, M-N Marson, Laurence Gérard, M. Lee, Hervé Watier, Éric Oksenhendler   +12 more
openalex   +1 more source

Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms [PDF]

, 2014
Vaheh Oganesyan, Melissa Damschroder, Kimberly E. Cook, Qing Li, Changshou Gao, Herren Wu, William F. Dall’Acqua   +6 more
openalex   +1 more source

miR‐140‐5p Overexpression Contributes to Oxidative Stress and Mitochondrial Dysfunction in Hutchinson‐Gilford Progeria Syndrome Fibroblasts Through NRF2 Pathway

Aging Cell, EarlyView.
This study identifies a novel molecular mechanism involving miR‐140‐5p that contributes to the pathogenesis of HGPS. By decreasing NRF2 expression, miR‐140‐5p overexpression results in downregulation of the NRF2/KEAP1/HO‐1 antioxidant pathway in HGPS fibroblasts, leading to increased oxidative stress and mitochondrial dysfunction, two hallmarks of ...
Léa Toury, Diane Frankel, Sara Nael, Mario Abaji, Léa Le Goff, Marie Basset, Coraline Airault, Bertrand Vernay, Elva María Novoa‐del‐Toro, Catherine Bartoli, Anaïs Baudot, Frederique Magdinier, Elise Kaspi, Patrice Roll   +13 more
wiley   +1 more source

Animal model of fetal and neonatal immune thrombocytopenia: role of neonatal Fc receptor in the pathogenesis and therapy [PDF]

, 2010
Pingguo Chen, Conglei Li, Sean Lang, Guangheng Zhu, Reheman Adili, Christopher M. Spring, John Freedman, Heyu Ni   +7 more
openalex   +1 more source

Single‐Cell RNA Sequencing Identifies Accumulation of Fcgr2b + Virtual Memory‐Like CD8 T Cells With Cytotoxic and Inflammatory Potential in Aged Mouse White Adipose Tissue

Aging Cell, EarlyView.
Age‐associated accumulation of Fcgr2b + VM‐like CD8 T cells within visceral adipose tissue contributes to inflammation. ABSTRACT Aging and obesity are associated with pro‐inflammatory changes in adipose tissue. Overlapping mechanisms, such as the infiltration of inflammatory macrophages and T cells into visceral adipose tissue, have been implicated in ...
Archit Kumar, Martin O'Brien, Vincent B. Young, Raymond Yung   +3 more
wiley   +1 more source