Results 111 to 120 of about 1,686,776 (208)
Crystal structure at 2.2 Å resolution of the MHC-related neonatal Fc receptor
, 1994 The three-dimensional structure of the rat neonatal Fc receptor (FcRn) is similar to the structure of molecules of the major histocompatibility complex (MHC).
Gastinel, Louis N. +4 more
core
Birth, EarlyView.CLASS checklist adherence was evaluated in a web‐based survey of 261 women who experienced stillbirth in Italy. Greater adherence to evidence‐based stillbirth care guidelines was associated with higher satisfaction and respectful care, as well as lower levels of perinatal grief and PTSD symptoms.
Claudia Ravaldi +3 more
wiley +1 more source
The neonatal Fc receptor does not modulate hepatitis C virus neutralization
, 2015 International audienceThe neonatal Fc receptor (FcRn) is the only receptor known to be able to transport IgG across cell barriers and may therefore modulate virus infection. FcRn is expressed efficiently in hepatocytes.
Arnoult, Christophe +7 more
core +1 more source
From haemostasis to immunity: The expanding frontiers of platelet biology
British Journal of Haematology, EarlyView.Platelets are versatile cells whose functions extend far beyond haemostasis and thrombosis, actively regulating innate and adaptive immunity, angiogenesis, lymphangiogenesis, liver regeneration, atherosclerosis and tumour metastasis. This demonstrates their central role in various physiological processes and multiple life‐threatening diseases ...
Xun Grace Wu, Nicole Tomei, Heyu Ni
wiley +1 more source
FcRn: the neonatal Fc receptor comes of age.
, 2007 The neonatal Fc receptor for IgG (FcRn) has been well characterized in the transfer of passive humoral immunity from a mother to her fetus. In addition, throughout life, FcRn protects IgG from degradation, thereby explaining the long half-life of this
Akilesh, S, Roopenian, D C
core +1 more source
Brain Pathology, EarlyView.Brain viral reservoirs were undetectable in neonatal SIV during the first 3 days post infection; antiretroviral therapy (ART) at 3 dpi prevented brain reservoir seeding and normalized metabolic function, highlighting the necessity of very early treatment to protect the developing CNS.
Li Ma +12 more
wiley +1 more source
Computational determination of the structure of rat Fc bound to the neonatal Fc receptor
, 1998 The available crystal structure for the complex between the Fc fragment of immunoglobulin G (IgG) and the neonatal Fc receptor (FcRn) was determined at low resolution and has no electron density for a large portion of the C_H2 domain of the Fc.
Vaughn, Daniel E. +4 more
core
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Journal of Preventive, Diagnostic and Treatment Strategies in MedicineMaternal immunization has increasingly been recognized as a practical strategy to protect infants during the earliest months of life, a period when the neonatal immune system remains immature and vulnerability to infection is high. Despite this progress,
Wiku Andonotopo +12 more
doaj +1 more source
The FEBS Journal, EarlyView.Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti +3 more
wiley +1 more source