Results 141 to 150 of about 4,213 (269)

Diabetes Advances Cardiomyocyte Senescence Through Interfering Rnd3 Expression and Function

Aging Cell, EarlyView.
Diabetes‐induced upregulation of miR‐103a‐3p suppresses Rnd3 expression in cardiomyocytes, thereby promoting the senescence‐associated secretory phenotype (SASP) through activation of the STAT3 signaling pathway, mediated by UPS‐induced degradation of p‐STAT3.
Linxu Wu, Xinglin Zhu, Shanshan Pan, Yan Chen, Cai Luo, Yangyang Zhao, Jingci Xing, Kaijia Shi, Shuya Zhang, Jiaqi Li, Jinxuan Chai, Xuebin Ling, Jianmin Qiu, Yan Wang, Zhihua Shen, Wei Jie, Junli Guo   +16 more
wiley   +1 more source

A variable number of tandem repeats polymorphism influences the transcriptional activity of the neonatal Fc receptor α‐chain promoter [PDF]

, 2006
Ulrich J. Sachs, Ines Socher, Christian G. Braeunlich, Hartmut Kroll, Gregor Bein, Sentot Santoso   +5 more
openalex   +1 more source

The use of financial incentives for smoking cessation in pregnant women: A parallel‐group randomised controlled trial protocol

Addiction, EarlyView.
Abstract Background and aims Smoking cessation during pregnancy results in short‐ and long‐term health benefits for the mother and infant. Despite public health policies and initiatives to reduce smoking, smoking in pregnancy remains unacceptably high in Australia, particularly among populations of high disadvantage.
Megan L. Hammersley, Gustaaf A. Dekker, Lyle C. Gurrin, Elizabeth A. Hoon, Stefanie Schurer, John W. Lynch, Marnie Aldred, Julia Dalton, Cherise J. Fletcher, Lisa G. Smithers   +9 more
wiley   +1 more source

Accelerated, Robust Lower-Field Neonatal MRI with Generative Models [PDF]

arXiv
Neonatal Magnetic Resonance Imaging (MRI) enables non-invasive assessment of potential brain abnormalities during the critical phase of early life development. Recently, interest has developed in lower field (i.e., below 1.5 Tesla) MRI systems that trade-off magnetic field strength for portability and access in the neonatal intensive care unit (NICU ...
arxiv  

In Suspected Fetal Growth Restriction, sFlt‐1/PlGF and PlGF May Have Value in Risk Stratification for Preterm Birth and Birthweight < 3rd Centile: A Blinded Cohort Study

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT We investigated the value of measuring sFlt‐1/PlGF in people with suspected fetal growth restriction (sFGR) without signs of preeclampsia at recruitment. Angiogenic biomarkers were considered positive when sFlt‐1/PlGF > 38 or PlGF < 100 pg/mL. Clinicians were blinded to the sFlt‐1/PlGF results.
Ruth C. E. Hughes, Pippa Kyle, Ian Phillips, Chris M. Florkowski, Joanna Gullam   +4 more
wiley   +1 more source

Activation of the JAK/STAT-1 Signaling Pathway by IFN-γ Can Down-Regulate Functional Expression of the MHC Class I-Related Neonatal Fc Receptor for IgG [PDF]

, 2008
Xindong Liu, Lilin Ye, Yu Bai, Habi Mojidi, Neil E. Simister, Xiaoping Zhu   +5 more
openalex   +1 more source

Dual Inhibition of Mast Cells and Thymic Stromal Lymphopoietin Using a Novel Bispecific Antibody, CDX‐622

Allergy, EarlyView.
SCF and TSLP expression are known to drive unique immune responses leading to the onset of allergic and inflammatory diseases. Here, we describe the characterization of a novel bsAb, CDX‐622, that targets SCF and TSLP. CDX‐622 inhibits MC functions through SCF starvation and Type 2 inflammatory responses via TSLP inhibition.
Michael B. Murphy, Laura Vitale, Thomas O'Neill, Deena M. Maurer, Linda Malenchek, Andrea Crocker, Colleen Patterson, Laura Mills‐Chen, Virginia Saley, Nicole M. Antczak, James M. Boyer, Kelly M. McManus, Noe Rico Montanari, Russell A. Hammond, Joel Goldstein, Lawrence J. Thomas, Tibor Keler, Diego Alvarado   +17 more
wiley   +1 more source

N-Glycan Moieties in Neonatal Fc Receptor Determine Steady-state Membrane Distribution and Directional Transport of IgG [PDF]

, 2009
Timothy Kuo, Eric J. de Muinck, Steven M. Claypool, Masaru Yoshida, Takashi Nagaishi, Victoria G. Aveson, Wayne I. Lencer, Richard S. Blumberg   +7 more
openalex   +1 more source

The Neonatal Fc Receptor Is Elevated in Monocyte-Derived Immune Cells in Pancreatic Cancer [PDF]

, 2022
Justin Thomas, Molly Torok, Kriti Agrawal, Timothy Pfau, Trang T. Vu, Justin Lyberger, Hsiaochi Chang, Alyssa Marie M. Castillo, Min Chen, Bryan Remaily, Kyeongmin Kim, Zhiliang Xie, Mary Dillhoff, Samuel K. Kulp, Gregory K. Behbehani, Zobeida Cruz–Monserrate, Latha P. Ganesan, Dwight H. Owen, Mitch A. Phelps, Christopher C. Coss, Thomas A. Mace   +20 more
openalex   +1 more source

Vaginal breech delivery in all‐fours position—Hands off instead of intervention: A prospective observational study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Vaginal breech delivery in all‐fours is safe for the newborn and in more than 50% possible without obstetric intervention. The results suggest that all‐fours has the potential as an emergency management maneuver for unplanned breech deliveries for unplanned births.
Gerhard Bogner, Johanna Schuller, Carina Gargitter, Eva Dölzlmüller, Thorsten Fischer, Claudius Fazelnia   +5 more
wiley   +1 more source