Results 181 to 190 of about 109,700 (295)

Engineering neonatal Fc receptor-mediated recycling and transcytosis in recombinant proteins by short terminal peptide extensions [PDF]

, 2012
Jonathan T. Sockolosky, Matthew Tiffany, Francis C. Szoka   +2 more
openalex   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

An engineered immunomodulatory IgG1 Fc suppresses autoimmune inflammation through pathways shared with i.v. immunoglobulin

The Journal of Clinical Investigation
Immunoglobulin G (IgG) antibodies in the form of high-dose intravenous immunoglobulin (IVIG) exert immunomodulatory activity and are used in this capacity to treat inflammatory and autoimmune diseases.
Sunny L. Sneed, Brian B. Reese, Ana F.S. Laureano, Sneha Ratnapriya, Isabella Fraschilla, Kate L. Jeffrey, Greg P. Coffey, Pamela B. Conley, Robert M. Anthony   +8 more
doaj   +1 more source

Efficiency of immunoglobulin G replacement therapy in common variable immunodeficiency: correlations with clinical phenotype and polymorphism of the neonatal Fc receptor

, 2012
Valérie Gouilleux‐Gruart, Helen Chapel, Sylvie Chevret, Mary Lucas, Marion Malphettes, Claire Fieschi, Smita Y. Patel, David Boutboul, M-N Marson, Laurence Gérard, M. Lee, Hervé Watier, Éric Oksenhendler, DEFI study group   +13 more
openalex   +2 more sources

Human serum albumin presents isoform variants with altered neonatal Fc receptor interactions [PDF]

, 2019
Y. Leblanc, Marie Berger, Alexander Seifert, Nicolas Bihoreau, Guillaume Chevreux   +4 more
openalex   +1 more source

Transcription Factor TCF12‐Mediated Maternal Gene Expressions in Mouse Oocyte Are Prerequisites of Successful Fertilisation and Zygotic Genome Activation

Cell Proliferation, EarlyView.
Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao, Chi Zhang, Zuo‐Qi Deng, Yue‐xin Qiu, Zhao Zhang, Heng‐Yu Fan, Jing Li, Hong‐Bo Wu   +7 more
wiley   +1 more source

The Neonatal Fc Receptor and Complement Fixation Facilitate Prophylactic Vaccine-Mediated Humoral Protection against Viral Infection in the Ocular Mucosa [PDF]

, 2017
Derek J. Royer, Meghan M. Carr, Hem R. Gurung, William P. Halford, Daniel J.J. Carr   +4 more
openalex   +1 more source

ISUOG Consensus Statement on sonographic assessment of the endometrium: how to perform a gynecological ultrasound scan and report the findings

Ultrasound in Obstetrics &Gynecology, EarlyView.
T.  Van den Bosch, R.  Heremans, C.  Landolfo, E.  Epstein, F. P. G.  Leone, T.  Bourne, D. Timmerman, Collaborators, J. Preisler, O. Rotenberg, H. Marret, G. Condous, J. L. Alcázar, D. Fischerová, U. Metzger, C. Van Pachterbeke, D. Franchi, M. Nisolle, J. Huirne, C. Fotopoulou, S. Goldstein   +20 more
wiley   +1 more source

Fc-empowered exosomes with superior epithelial layer transmission and lung distribution ability for pulmonary vaccination

Bioactive Materials
Mucosal vaccines offer potential benefits over parenteral vaccines for they can trigger both systemic immune protection and immune responses at the predominant sites of pathogen infection.
Fan Meng, Haonan Xing, Jingru Li, Yingqi Liu, Li Tang, Zehong Chen, Xiran Jia, Zenglin Yin, Jing Yi, Mei Lu, Xiuli Gao, Aiping Zheng   +11 more
doaj   +1 more source

Transport of antibody into the skin is only partially dependent upon the neonatal Fc-receptor. [PDF]

PLoS One, 2023
Nasir G, Sinnis P.
europepmc   +1 more source