Results 181 to 190 of about 4,213 (269)

The neonatal Fc receptor (FcRn) is not required for IVIg or anti-CD44 monoclonal antibody–mediated amelioration of murine immune thrombocytopenia

, 2011
Andrew R. Crow, Sara J. Suppa, Xi Chen, Patrick J. Mott, Alan H. Lazarus   +4 more
openalex   +1 more source

The RhoA guanine exchange factor ABR: a glucose‐sensitive mediator of actin reorganization in feto‐placental arterial endothelial cells altered by gestational diabetes mellitus

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of proposed relationship between hyperglycaemia, gestational diabetes mellitus (GDM), active BCR‐related (ABR), RhoA and actin organization of feto‐placental arterial endothelial cells (fpEC). Hyperglycaemia upregulates ABR, which in turn increases RhoA activation.
Silvija Tokic, Boris Novakovic, Barbara Leopold‐Posch, Magdalena Mühlberger, Denise Hoch, Jelena Lögl, Eva M. Bernhart, Richard Saffery, Gernot Desoye, Ursula Hiden   +9 more
wiley   +1 more source

The Fragile X Messenger Ribonucleoprotein 1 Regulates the Morphology and Maturation of Human and Rat Oligodendrocytes

Glia, Volume 73, Issue 6, Page 1203-1220, June 2025.
Main Points Loss of FMRP impairs human and rat oligodendrocyte (OL) morphology in vitro. FMRP‐deficient OLs show impaired maturation when engrafted in hypomyelinated mice. Rat Fmr1 knockout OLs show a delay in myelin sheath formation in vivo. ABSTRACT The Fragile X Messenger Ribonucleoprotein (FMRP) is an RNA binding protein that regulates the ...
Vidya Ramesh, Eleni Tsoukala, Ioanna Kougianou, Zrinko Kozic, Karen Burr, Biju Viswanath, David Hampton, David Story, Bharath Kumar Reddy, Rakhi Pal, Owen Dando, Peter C. Kind, Sumantra Chattarji, Bhuvaneish T. Selvaraj, Siddharthan Chandran, Lida Zoupi   +15 more
wiley   +1 more source

Efficiency of immunoglobulin G replacement therapy in common variable immunodeficiency: correlations with clinical phenotype and polymorphism of the neonatal Fc receptor

, 2012
Valérie Gouilleux‐Gruart, Helen Chapel, Sylvie Chevret, Mary Lucas, Marion Malphettes, Claire Fieschi, Smita Y. Patel, David Boutboul, M-N Marson, Laurence Gérard, M. Lee, Hervé Watier, Éric Oksenhendler   +12 more
openalex   +2 more sources

N‐Acety‐L‐Cysteine Alleviates Isoflurane‐Triggered Neuronal Cell Parthanatos by Suppressing Reactive Oxygen Species Accumulation Through the Induction of c‐Jun N‐Terminal Kinase Signaling Pathway Inhibition

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 5, May 2025.
This study demonstrates that isoflurane induces parthanatos in developing neuronal cells through oxidative stress mechanisms, as evidenced by increased PARP‐1, AIF, and PAR levels, along with elevated ROS and activated JNK signaling pathways. Importantly, N‐Acetylcysteine (NAC) pretreatment mitigates these effects, reducing ROS accumulation and ...
Nan Liu, Ya Liu, Xuedong Wang, Ming Liu, Yingying Wang, Chunsheng Feng, Meihua Piao   +6 more
wiley   +1 more source

Characterization of the Rabbit Neonatal Fc Receptor (FcRn) and Analyzing the Immunophenotype of the Transgenic Rabbits That Overexpresses FcRn

, 2012
Ana Paula Catunda Lemos, Judit Cervenak, Balázs Bender, Orsolya Ivett Hoffmann, Mária Baranyi, Andrea Kerekes, Anita Farkas, Zsuzsanna Bösze, László Hiripi, Imre Kacskovıcs   +9 more
openalex   +2 more sources

Podocyte-specific knockout of the neonatal Fc receptor (FcRn) results in differential protection depending on the model of immune-mediated kidney disease

, 2020
James Dylewski, Pantipa Tonsawan, Gabriela E. Garcia, Linda Lewis, Judith Blaine   +4 more
openalex   +1 more source

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

Endothelial damage and complement dysregulation in fetuses from pregnancies complicated by preeclampsia

Acta Obstetricia et Gynecologica Scandinavica, Volume 104, Issue 5, Page 829-838, May 2025.
Preeclampsia fetuses show an altered profile of endothelial damage and complement biomarkers, like increased adhesion molecules, prothrombotic state, oxidative stress, and reduced complement membrane attack complex deposition on endothelial cells. Abstract Introduction Our objective was to evaluate the endothelial function profile and complement system
Alex Ramos, Lina Youssef, Patricia Molina, Julia Martinez‐Sanchez, Ana Belen Moreno‐Castaño, Miquel Blasco, Blanca De Moner, Marta Tortajada, Marta Camacho, Maria Borrell, Francesca Crovetto, Marc Pino, Gines Escolar, Enric Carreras, Eduard Gratacos, Maribel Diaz‐Ricart, Marta Palomo, Fatima Crispi   +17 more
wiley   +1 more source

Interaction with Both Domain I and III of Albumin Is Required for Optimal pH-dependent Binding to the Neonatal Fc Receptor (FcRn)

, 2014
Kine Marita Knudsen Sand, Malin Bern, Jeannette Nilsen, Bjørn Dalhus, Kristin Støen Gunnarsen, Jason Cameron, Algirdas Grevys, Karen Bunting, Inger Sandlie, Jan Terje Andersen   +9 more
openalex   +1 more source