Results 211 to 220 of about 4,213 (269)

678 The neonatal Fc receptor is elevated in monocyte-derived immune cells in pancreatic cancer

Journal for ImmunoTherapy of Cancer, 2021
Justin Thomas, Min Chen, Thomas Mace, Mitch Phelps, Molly Torok, Kriti Agrawal, Trang Vu, Dwight Owen, Alyssa Castillo, Bryan Remaily, Kyeongmin Kim, Zhiliang Xie, Samuel Kulp, Christopher Coss   +13 more
doaj   +1 more source

Pharmacokinetics and Pharmacodynamics of Nipocalimab, a Neonatal Fc Receptor Blocker, in Healthy Japanese Volunteers [PDF]

Nobuko Matsushima, Sayori Shibata, Jocelyn H. Leu, An Vermeulen, Jay Duffner, Leona Ling, Lisa Barrie Schwartz, Hideo Harigae   +7 more
openalex   +1 more source

Outcome Indicators for Evaluating Interventions by Advanced Practice Nurses Specialising in Acute Pain: A Scoping Review

Nursing Open, Volume 12, Issue 4, April 2025.
ABSTRACT Aim To identify outcome indicators to evaluate interventions delivered by advanced practice nurses specialising in acute pain as reported in the scientific literature. Design Scoping review. Data Sources Three databases (PubMed, Scopus and CINAHL) were systematically searched in December 2023 to identify studies published between 1996 and 2023.
Patricia Barroso‐Castaño, Sandra Cabrera‐Jaime, Maria Feijoo‐Cid, Ariadna Huertas‐Zurriaga, Llúcia Benito Aracil   +4 more
wiley   +1 more source

Cellular Communication Network Protein 2 in the Right Ventricle of Pulmonary Arterial Hypertension

Pulmonary Circulation, Volume 15, Issue 2, April 2025.
ABSTRACT Cellular communication network 2 (CCN2) is a secreted matricellular protein associated with pulmonary arterial hypertension (PAH) but has not been studied relative to PAH severity, outcomes, or right ventricle (RV) structure and function in a large human cohort and preclinical animal model. This study assessed the associations between CCN2 and
Carly E. Byrd, Jennifer E. Schramm, Jun Yang, Allan E. Barnes, Megan Griffiths, Anjira S. Ambade, Darin T. Rosen, Ilton M. Cubero Salazar, Catherine E. Simpson, Ryan J. Tedford, Steven Hsu, Dhananjay Vaidya, Todd M. Kolb, Michael W. Pauciulo, William C. Nichols, David D. Ivy, Eric D. Austin, Paul M. Hassoun, Rachel L. Damico, Allen D. Everett   +19 more
wiley   +1 more source

Antibody‐Nanoparticle Conjugates in Therapy: Combining the Best of Two Worlds

Small, Volume 21, Issue 15, April 16, 2025.
Antibody‐nanomaterial conjugates (ANCs) are an emerging therapeutic class combining the precise targeting specificity of antibodies with the versatility and functionality of nanomaterials. This review summarizes ANC design, synthesis, and potential therapeutic applications in this rapidly advancing field.
Aniruddha Adhikari, Irene A. Chen
wiley   +1 more source

The Omics Landscape of Long COVID—A Comprehensive Systematic Review to Advance Biomarker, Target and Drug Discovery

Allergy, Volume 80, Issue 4, Page 932-948, April 2025.
ABSTRACT An estimated 10% of coronavirus disease (COVID‐19) survivors suffer from persisting symptoms referred to as long COVID (LC), a condition for which approved treatment options are still lacking. This systematic review (PROSPERO: CRD42024499281) aimed to explore the pathophysiological mechanisms underlying LC and potential treatable traits across
Nadia Baalbaki, Elise M. A. Slob, Samuel W. Kazer, Mahmoud I Abdel‐Aziz, Harm Jan Bogaard, Korneliusz Golebski, Anke H. Maitland‐van der Zee   +6 more
wiley   +1 more source

Efficacy and Safety of Efgartigimod for Patients With Myasthenia Gravis in a Real‐World Cohort of 77 Patients

CNS Neuroscience &Therapeutics, Volume 31, Issue 4, April 2025.
This real‐world study of 77 myasthenia gravis (MG) patients treated with efgartigimod showed rapid symptom improvement across disease severities. Sustained efficacy was achieved with repeated cycles, positioning efgartigimod as a promising MG therapy combining swift response and durable maintenance benefits. ABSTRACT Aims Efgartigimod, a first‐in‐class
Sijia Hao, Zhe Ruan, Rongjing Guo, Qingqing Wang, Xiaoxi Huang, Chao Sun, Huanhuan Li, Ting Gao, Yonglan Tang, Xiangqi Cao, Yu Liu, Zhuyi Li, Ting Chang   +12 more
wiley   +1 more source

Cognitive and academic outcomes in children with myelin oligodendrocyte glycoprotein antibody‐associated disease

Developmental Medicine &Child Neurology, Volume 67, Issue 4, Page 529-536, April 2025.
A large proportion of patients with pediatric‐onset myelin oligodendrocyte glycoprotein antibody‐associated disease experience academic difficulties, leading to a higher risk of academic and educational intervention after disease onset. These interventions are more frequent in patients with acute disseminated encephalomyelitis phenotype, but can also ...
Audrey Mittelman, Julie Pique, Vincent Desportes, Kumaran Deiva, Anne‐Lise Poulat, Romain Marignier   +5 more
wiley   +1 more source

Therapeutic targeting of TGF‐β in lung cancer

The FEBS Journal, Volume 292, Issue 7, Page 1520-1557, April 2025.
Here, we discuss how lung cancer treatment can be transformed by targeting TGF‐β for better outcomes. Inhibiting TGF‐β signaling halts tumor growth, boosts immune response, and enhances treatment efficacy. By tackling TGF‐β's role in epithelial–mesenchymal transition (EMT) and immune evasion, this approach opens new avenues for more effective lung ...
Sajjad Aftabi, Amir Barzegar Behrooz, Marco Cordani, Niloufar Rahiman, Mohammadamin Sadeghdoust, Farnaz Aligolighasemabadi, Stephen Pistorius, Seyedeh Hoda Alavizadeh, Nima Taefehshokr, Saeid Ghavami   +9 more
wiley   +1 more source

Review Article: Albumin and Its Role in Inflammatory Bowel Disease: The Old, the New, and the Future

Journal of Gastroenterology and Hepatology, Volume 40, Issue 4, Page 808-820, April 2025.
ABSTRACT Background Circulating albumin concentrations are frequently measured in clinical practice. This review explores biochemical properties and physiological roles of albumin, its place in nutritional assessment, current understanding of perturbed circulating concentrations, and role in clinical management, with special focus on patients with ...
Karla Cameron, Anke L. Nguyen, David J. Gibson, Mark G. Ward, Miles P. Sparrow, Peter R. Gibson   +5 more
wiley   +1 more source