[The neonatal receptor Fc gamma(FcRn)--structure and function].
The neonatal Fc receptor (FcRn) is named for the source from which it was first purified, the intestinal epithelium of neonatal rats. The human homologue of FcRn was first found in the placenta, where is presumably involved in transfer of maternal IgG to the fetus.
openaire +1 more source
FP021RENAL KNOCKOUT OF THE NEONATAL FC RECEPTOR (FCRN) IS NOT ASSOCIATED WITH CHANGES IN ALBUMIN METABOLISM [PDF]
Esben Axelgaard +3 more
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Intravaginal Administration of Fc-Fused IL7 Suppresses the Cervicovaginal Tumor by Recruiting HPV DNA Vaccine-Induced CD8 T Cells [PDF]
Purpose: The induction of tissue-localized virus-specific CD8 T-cell response is essential for the development of an effective therapeutic vaccine against genital diseases, such as cervical cancer and genital herpes.
Choi, DH +9 more
core +1 more source
Cellular expression and crystal structure of the murine cytomegalovirus MHC-Iv glycoprotein, m153 [PDF]
Mouse cytomegalovirus (MCMV), a β-herpesvirus that establishes latent and persistent infections in mice, is a valuable model for studying complex virus-host interactions.
Balbo, Andrea +10 more
core +1 more source
FcRn regulates antigen presentation in dendritic cells downstream of DEC205-targeted vaccines
Dendritic cell (DC)-targeted vaccination is a new mode of antigen delivery that relies on the use of monoclonal antibodies (mAb) to target antigen to specific DC subsets.
Christophe Macri +9 more
doaj +1 more source
La production de colostrum chez la brebis : évaluation de la variabilité de la concentration et de la masse d’immunoglobulines G1(IgG1) [PDF]
Chez la brebis, la placentation syndesmochoriale impose une prise colostrale précoce et de qualité pour la survie de l’agneau. L’objectif de ces travaux était d’apporter des éléments de réponse sur la faisabilité d’un phénotypage rapide et peu couteux ...
Jacquet, Amélie, Rousset, Anne-Lise
core
Intranasal Introduction of Fc-Fused Interleukin-7 Provides Long-Lasting Prophylaxis against Lethal Influenza Virus Infection [PDF]
Influenza A virus (IAV) infection frequently causes hospitalization and mortality due to severe immunopathology. Annual vaccination and antiviral drugs are the current countermeasures against IAV infection, but they have a limited efficacy against new ...
Ahn, SS +13 more
core +1 more source
Podocyte-specific knockout of the neonatal Fc receptor (FcRn) results in differential protection depending on the model of immune-mediated kidney disease [PDF]
James Dylewski +4 more
openalex +1 more source

