Results 21 to 30 of about 417,028 (237)
Cancer Stem Cells Can Arise From Differentiated Neoplastic Cells [PDF]
Rahul Jandial, Dawn Waters, Mike Y Chen
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Normal & neoplastic stem cell (ML15) [PDF]
Irving L. Weissman
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Background Mesenchymal stem cells (MSCs) secrete a cocktail of growth factors and cytokines, which could promote tissue regeneration and wound healing.
Honorata Kraskiewicz+9 more
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Endothelial progenitor cells (EPCs) and mesenchymal stem/stromal cells (MSCs) are associated with maintaining tissue homeostasis and tissue repair. Both types of cells contribute to tissue regeneration through the secretion of trophic factors (alone or ...
Agnieszka Krawczenko+6 more
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von Hippel-Lindau disease-associated hemangioblastomas are derived from embryologic multipotent cells. [PDF]
BACKGROUND: To determine the origin of the neoplastic cell in central nervous system (CNS) hemangioblastomas in von Hippel-Lindau disease (VHL) and its role in tumor formation and distribution, we characterized and differentiated neoplastic cells from ...
Deric M Park+12 more
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The E. Donnall Thomas Lecture: Normal and Neoplastic Stem Cells [PDF]
AbstractDr. Irving Weissman was the honored E. Donnall Thomas lecturer at the Tandem BMT Meetings, held on February 10, 2007, at Keystone, Colorado. Dr. Weissman has been a major player, and has provided us with enormous insight into many areas of biology, dating back to his high school days in Montana.
Irving L. Weissman
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Association between CD133 expression and clinicopathological profile in colorectal cancer [PDF]
Aim To investigate CD133 expression and its relationship to clinicopathological profile in colorectal cancer (CRC) patients. Methods This cross-sectional study was performed at the Internal Medicine Department, School of Medicine, Adam Malik General ...
Imelda Rey+3 more
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YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells [PDF]
Background: The brain cancer stem cell (CSC) model describes a small subset of glioma cells as being responsible for tumor initiation, conferring therapy resistance and tumor recurrence.
Beier, Dagmar+9 more
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A systematic approach to cancer: evolution beyond selection. [PDF]
Cancer is typically scrutinized as a pathological process characterized by chromosomal aberrations and clonal expansion subject to stochastic Darwinian selection within adaptive cellular ecosystems.
Miller, William B, Torday, John S
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Mist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche [PDF]
The regulation and stem cell origin of normal and neoplastic gastric glands are uncertain. Here, we show that Mist1 expression marks quiescent stem cells in the gastric corpus isthmus. Mist1(+) stem cells serve as a cell-of-origin for intestinal-type cancer with the combination of Kras and Apc mutation and for diffuse-type cancer with the loss of E ...
Yoku Hayakawa+29 more
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