Results 91 to 100 of about 314,513 (244)

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

Arthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Braf mutation induces rapid neoplastic transformation in the aged and aberrantly methylated intestinal epithelium. [PDF]

Gut, 2022
Fennell L, Kane A, Liu C, McKeone D, Hartel G, Su C, Bond C, Bettington M, Leggett B, Whitehall V.   +9 more
europepmc   +1 more source

Identification of tumor initiating cells and early marker genes in normal colonic epithelium that lead to neoplastic transformation [PDF]

Sangeeta Jaiswal, Stephanie The, Tse-Shao Chang, Jiaqi Shi, Thomas D. Wang   +4 more
openalex   +1 more source

Transformation by inorganic arsenic compounds of normal Syrian hamster embryo cells into a neoplastic state in which they become anchorage‐independent and cause tumors in newborn hamsters [PDF]

, 2002
Masayuki Takahashi, J. Carl Barrett, Takeki Tsutsui   +2 more
openalex   +1 more source

Bacterial Pigments as Potential Antitumor Agents Against Gastrointestinal Cancers: A Comprehensive Systematic Review

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Gastrointestinal cancers (GICs) constitute one of the leading causes of cancer‐related morbidity and mortality worldwide. Despite currently available therapeutic strategies, new approaches and procedures are needed for their prevention and treatment.
Raúl Vergara, Ricardo F. S. Pereira, Carla C. C. R. de Carvalho, Jose Prados, Consolación Melguizo, Raul Ortiz   +5 more
wiley   +1 more source

Cyclooxygenase-2 induces neoplastic transformation by inhibiting p53-dependent oncogene-induced senescence. [PDF]

Sci Rep, 2021
Lee HJ, Kim SR, Jung YJ, Han JA.
europepmc   +1 more source

Elevated Levels of Thymidylate Synthase Linked to Neoplastic Transformation of Mammalian Cells [PDF]

, 2004
Donna Voeller, Lambratu Rahman, Maria Zajac‐Kaye   +2 more
openalex   +1 more source

Model‐informed precision dosing of carboplatin in cancer patients by leveraging myelosuppression data from electronic health records

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This study aimed to develop and validate a population pharmacokinetic‐pharmacodynamic (pop‐PK‐PD) model to describe carboplatin‐induced myelosuppression in cancer patients and support dose individualization. Methods Data from 580 cancer patients treated with carboplatin at Amsterdam UMC between 2019 and 2022 were used for model ...
Alessandro De Carlo, Elena Maria Tosca, Mirjam Crul, Tim Schutte, Lia van Zuijlen, Idris Bahce, Medhat M. Said, Jan Buter, Harmen Huls, Paolo Magni, Imke Bartelink   +10 more
wiley   +1 more source

Anabolic Steroids-Driven Regulation of Porcine Ovarian Putative Stem Cells Favors the Onset of Their Neoplastic Transformation. [PDF]

Int J Mol Sci, 2021
Gorczyca G, Wartalski K, Wiater J, Samiec M, Tabarowski Z, Duda M.   +5 more
europepmc   +1 more source

Radiation-induced neoplastic transformation of human cells.

Scanning microscopy, 1993
Ionizing radiation can induce cancers in humans and animals and can cause in vitro neoplastic transformation of various rodent cell systems. However, numerous attempts to achieve neoplastic transformation of human cells by radiation have generally proven unsuccessful.
Rhim, J. S., Thraves, P., Dritschilo, A., Kuettel, M. R., Lee, M. -S.   +4 more
openaire   +2 more sources