Results 81 to 90 of about 333,688 (297)

Microtubule Protein β_III-Tubulin: Structure, Expression and Functions in Normal and Tumor Cells

Антибиотики и Химиотерапия, 2020
The present review contains data on microtubular protein ßIII-tubulin (TUBB3): its structure, functions, role in tumor progression, expression in normal cells and in neural and epithelial tumors of different origins.
I. A. Mamichev, T. A. Bogush, E. A. Bogush, N. S. Terentyeva, V. Y. Kirsanov, M. M. Davydov   +5 more
doaj  

Squamous cell carcinoma arising in ovarian mature cystic teratoma: report of three cases

Journal of Pathology of Nepal, 2012
Malignant transformation of mature cystic teratoma of the ovary is rare. A wide variety of malignant tumors may arise within benign mature cystic teratoma.
R Bashyal, MC Lee
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Cytologic Manifestations of Neoplastic Transformation In Vitro 1 [PDF]

, 1969
SUMMARY-Our objective was to test whether cytologic diagnoses of neoplastic transformation could be made accurately on cultured cells in vitro. Cytologic criteria of malignancy as applied to tissues or exfoliated cells in vivo served as guidelines for ...
Barbara E. Barker, Katherine K. Sanford, Barker, B E, Sanford, K K   +3 more
core  

Related Data for: EZH2 promotes neoplastic transformation through VAV interaction-dependent extranuclear mechanisms [PDF]

, 2018
This dataset contains RNA-seq data and supplementary data relating to the journal article "EZH2 promotes neoplastic transformation through VAV interaction-dependent extranuclear mechanisms" which was published in Ocogene on 25 Jan ...
Lin, Valerie Chun Ling, Yau, Yin Hoe, Venkatesan, Nandini, Allahverdi, Abdollah, Tan, Kuan Pern, Chung, Hwa Hwa, Wong, Jong Fu, Cukuroglu, Egin, Su, I-Hsin, Göke, Jonathan, Nordenskiold, Lars, Madhusudhan, M.S., Shochat, Susana Geifman   +12 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Metabolism and Epigenetic Interplay in Cancer: Regulation and Putative Therapeutic Targets

Frontiers in Genetics, 2018
Alterations in the epigenome and metabolism affect molecular rewiring of cancer cells facilitating cancer development and progression. Modulation of histone and DNA modification enzymes occurs owing to metabolic reprogramming driven by oncogenes and ...
Vera Miranda-Gonçalves, Ana Lameirinhas, Ana Lameirinhas, Rui Henrique, Rui Henrique, Rui Henrique, Carmen Jerónimo, Carmen Jerónimo   +7 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Transformation enhancing factors and fibronectin degradation products as possible tumor markers. [PDF]

, 1983
Transformation enhancing factors and fibronectin degradation products as possible tumor ...
Vartio T., BARLATI, Sergio, DE PETRO, Giuseppina, Vaheri A.   +3 more
core  

Log₁₀ scale plot of the cancer response activity (CRA) vs. cancer cell type (stage of neoplastic transformation). [PDF]

, 2017
Log10 scale plot of the cancer response activity (CRA) vs. cancer cell type (stage of neoplastic transformation).
Karin Scarpinato (3710359), Josiah Low (3710356), Tracey Pu (3710353), Daniel Nelli (3710344), Justin Sigley (3710347), Martin Guthold (270306), Keith Bonin (227243), John Jarzen (3710350)   +7 more
core   +1 more source