Results 71 to 80 of about 333,688 (297)
"Transformation of chronic myelogenous leukemia to Multiple Myeloma: A case report " [PDF]
Acta Medica Iranica, 2003 Chronic myelogenous leukemia (CML) is a stem cell disorder sometimes associated with lymphoproliferative disorders. CML may precede a lymphoproliferative disorder.
"Ghavamzadeh A +5 more
doaj +1 more source
EMBO Molecular Medicine, 2013 Initiating neoplastic cell transformation events are of paramount importance for the comprehension of regeneration and vanguard oncogenic processes but are difficult to characterize and frequently clinically overlooked.
Gonçalo Regalo, Achim Leutz
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Adaptive Response Against Spontaneous Neoplastic Transformation In Vitro Induced by Ionizing Radiation [PDF]
, 2003 The goal of this project was to establish a dose response curve for radiation-induced neoplastic transformation of HeLa x skin fibroblast human hybrid cells in vitro under experimental conditions were an adaptive response, if it were induced, would have ...
J. Leslie Redpath, Ph.D.
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Alternative Splicing and Its Impact as a Cancer Diagnostic Marker [PDF]
Genomics & Informatics, 2012 Most genes are processed by alternative splicing for gene expression, resulting in the complexity of the transcriptome in eukaryotes. It allows a limited number of genes to encode various proteins with intricate functions.
Yun-Ji Kim, Heui-Soo Kim
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Expression of vascular endothelial growth factor in dogs with Spirocerca lupi-associated neoplastic transformation [PDF]
, 2012 Dissertation (MMedVet)--University of Pretoria, 2012.Tumour development is dependent upon the formation of an adequate blood supply through angiogenesis.
core
Genomics define neoplastic transformation in multiple myeloma precursor conditions [PDF]
Background: Multiple myeloma (MM) is always preceded by monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM). While these precursor conditions are asymptomatic, they are not entirely benign and carry a lifelong ...
Castellano, Giancarlo +43 more
core +1 more source
Revista Chilena de Obstetricia y Ginecología, 2006 Se presenta una revisión bibliográfica del mecanismo de infección y transformación neoplásica producida por el virus papiloma humano, de alto riesgo oncogénico, en el epitelio cervical.
René Rivera Z +4 more
doaj