Results 91 to 100 of about 331,839 (297)

Neoplastic transformation of endocervicosis into an extraovarian mucinous cystadenocarcinoma

, 2011
Although extraovarian mucinous cystadenocarcinomas resemble primary ovarian carcinomas, both histologically and clinically, their specific etiology is not clear.
Kruse, Arnold-Jan, Slangen, Brigitte, Tina Pirens, Jan P.A. Baak, Dunselman, Gerard A, Bakers, Frans C. H., Arnold-Jan Kruse, Brigitte Slangen, Dunselman, Gerard A., Bakers, Frans CH, Van de Vijver, Koen, Baak, Jan P. A., Koen Van de Vijver, Frans C.H. Bakers, Baak, Jan PA, Gerard A. Dunselman, Pirens, Tina   +16 more
core   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Role of Repair Processes in Neoplastic Transformation Induced by Ionizing Radiation in C3H/10T1/2 Cells [PDF]

, 1984
The paper discusses the mechanisms underlying the induction and modulation of neoplastic transformation by the type and mode of radiation delivery. Those features of transformation in vitro characteristic of induction by ionizing radiation are described.
Hill, C. K., Elkind, M. M., Han, A.
core  

Abstract 2227: Fgf2 from visceral adipose tissue stimulates neoplastic transformation of nonmalignant epithelial cells

, 2017
Background: Adiposity plays a crucial role in the pathogenesis and prognosis of different types of cancers. Epidemiological evidence suggests visceral adipose tissue (VAT) and high-fat diets (HFD) are associated with increased cancer risk however the ...
Vanessa Benham, Blair Bullard, Jamie J. Bernard, Elena Y. Demireva, Debrup Chakraborty   +4 more
core   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Isolation of genetic suppressor elements promoting neoplastic transformation.

, 1996
Isolation of genetic suppressor elements promoting neoplastic ...
Ilya A. Mazo (7961435)
core  

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

The role of vitamin D in dogs with Spirocerca lupi-associated neoplastic transformation [PDF]

, 2013
Dissertation (MMedVet)--University of Pretoria, 2013.Spirocercosis in dogs is characterized by oesophageal nodules that readily undergo neoplastic transformation, but the pathogenesis of this neoplastic transformation is poorly understood.

core  

Actin isoforms and neoplastic transformation

Advances in Molecular Oncology, 2017
The cytoplasmic actins (β and γ) play crucial roles during key cellular processes like adhesion, migration, polarization and cytokinesis. The understanding of their specific underlying mechanisms would be of major relevance not only for fundamental research but also for clinical applications, since modulations of actin isoforms are directly or ...
V. B. Dugina, G. S. Shagieva, N. V. Khromova, P. B. Kopnin   +3 more
openaire   +3 more sources

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source