Results 71 to 80 of about 304,509 (373)

Feminization and severe pancytopenia caused by testicular neoplasia in a cryptorchid dog [PDF]

, 2016
In this case report, a paraneoplastic syndrome caused by testicular neoplasia in a ten-year-old cryptorchid dog is described. Feminization and pancytopenia were observed, resulting from the testicular neoplastic production of estrogens.
Hebbelinck, Lien, Kitshoff, Adriaan, Paepe, Dominique, Vandenabeele, Sophie   +3 more
core  

Neoplastic Transformation by Notch Requires Nuclear Localization [PDF]

Molecular and Cellular Biology, 2000
Notch proteins are plasma membrane-spanning receptors that mediate important cell fate decisions such as differentiation, proliferation, and apoptosis. The mechanism of Notch signaling remains poorly understood. However, it is clear that the Notch signaling pathway mediates its effects through intercellular contact between neighboring cells.
Anthony J. Capobianco, Shawn Jeffries
openaire   +2 more sources

Chromoblastomycosis evolving to sarcomatoid squamous cell carcinoma: A case report

Dermatology Reports, 2021
Chromoblastomycosis (CMB) is a cutaneous fungal infection caused by dematiaceous fungi. According to the World Health Organization CMB has been elected as a tropical disease, and it is prevalent in tropical and subtropical regions.
Walter Belda Jr., Paulo Ricardo Criado, Paula Casteleti, Luiz Felipe Domingues Passero   +3 more
doaj   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

The adverse effects of the sun on the skin : a review [PDF]

, 1998
Solar radiation causes a variety of biologic effects in the skin which are predominantly harmful. The only recognised beneficial effect is that of endogenous photosynthesis of vitamin D from its precursors in the skin, the importance of which is greatly ...
Keefe, M., Scerri, Lawrence
core  

Lung adenocarcinoma originates from retrovirus infection of proliferating type 2 pneumocytes during pulmonary post-natal development or tissue repair [PDF]

, 2011
Jaagsiekte sheep retrovirus (JSRV) is a unique oncogenic virus with distinctive biological properties. JSRV is the only virus causing a naturally occurring lung cancer (ovine pulmonary adenocarcinoma, OPA) and possessing a major structural protein that ...
A Giangreco, A Harris, A Ortin, A Winkelmann, AB Bahnson, AD Miller, AL Payne, AS Zolotukhin, B Chessa, BB Zhou, BJ Bradley, C Cousens, C Johnson, CF Kim, CG Plopper, Claudio Murgia, D Salvatori, DG Miller, DI Nisbet, DW Verwoerd, E Beytut, EL Rawlins, EL Rawlins, F Arnaud, F Arnaud, F Schwenter, G Zavala, Gabriella Di Francesco, H Fan, JA Platt, JA Whitsett, JC DeMartini, JE Donello, JE Visvader, JM Coffin, JM Sharp, JM Sharp, JP Scheerlinck, K McGee-Estrada, K McGee-Estrada, K McGee-Estrada, K Perk, K Quade, L Naldini, LH Rosai JaS, M Bray, M Caporale, M Caporale, M Caporale, M De Las Heras, M De las Heras, M Palmarini, M Palmarini, M Palmarini, M Palmarini, M Palmarini, M Palmarini, M Palmarini, M Palmarini, M Palmarini, Marcelo de las Heras, Marco Caporale, Massimo Palmarini, MF Clarke, MH Kubbutat, Michael Emerman, MJ Holland, N Maeda, N Maeda, N Maeda, N Rosenberg, Nicola Ferri, Ousman Ceesay, P Banerjee, PF Lewis, RM Dakessian, RP Hill, S Zaffran, SK Rai, SK Rai, SK Wootton, SK Wootton, SL Kauffman, SL Liu, SL Liu, SL Liu, SL Liu, T Reya, T Roe, TB Zeltner, TB Zeltner, TE Allen, U O'Doherty, Vincenzo Varasano   +93 more
core   +5 more sources

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Common features between neoplastic and preneoplastic lesions of the biliary tract and the pancreas [PDF]

, 2019
The bile duct system and pancreas show many similarities due to their anatomical proximity and common embryological origin. Consequently, preneoplastic and neoplastic lesions of the bile duct and pancreas share analogies in terms of molecular ...
Alvaro, D, Arcidiacono, Pg, Capurso, G., Cardinale, V, Carpino, G, Doglioni, C, Gaudio, E, Pedica, F, Petrone, Mc, Severi, C, Zaccari, P   +10 more
core   +1 more source

A rare case of carcinoid tumor in a tailgut cyst [PDF]

Journal of Community Hospital Internal Medicine Perspectives, 2016
Tailgut cysts are rare congenital lesions that arise from the failure of regression of the embryological tailgut. We report a case of neoplastic transformation of tailgut cyst to carcinoid tumor which is exceedingly uncommon.
Asad Jehangir, Brian H. Le, Frank M Carter   +2 more
doaj   +1 more source

Quantitative analysis of collagen remodeling in pancreatic lesions using computationally translated collagen images derived from brightfield microscopy images [PDF]

arXiv, 2023
The changes in stromal collagen play a crucial role during the pathogenesis and progression of pancreatic intraepithelial neoplasm (PanIN) to pancreatic ductal adenocarcinoma (PDAC) while misdiagnosis of PanIN is common because of the resemblance to chronic pancreatitis (CP) in its symptoms and subsequent evaluations similarities.
arxiv