Results 31 to 40 of about 16,884 (255)

Neopterin measurement in clinical diagnosis [PDF]

Journal of Clinical Pharmacy and Therapeutics, 2001
Neopterin is a marker associated with cell-mediated immunity. It is produced in monocytes/macrophages primarily upon stimulation with interferon-gamma. Due to its chemical structure, neopterin belongs to the class of pteridines. It is excreted in an unchanged form via the kidneys. Serum levels above 10 nmol/L are regarded as elevated.
A, Berdowska, K, Zwirska-Korczala
openaire   +2 more sources

Metabolomics Identifies multiple candidate biomarkers to diagnose and stage human African trypanosomiasis [PDF]

, 2016
Treatment for human African trypanosomiasis is dependent on the species of trypanosome causing the disease and the stage of the disease (stage 1 defined by parasites being present in blood and lymphatics whilst for stage 2, parasites are found beyond the
Barrett, Michael P., Bisser, Sylvie, Biéler, Sylvain, Cattanach, Amy M., Courtioux, Bertrand, Daly, Rónán, Ndung’u, Joseph M., Vincent, Isabel M.   +7 more
core   +5 more sources

Detection of neopterin in tear samples

Pteridines, 2016
The main goal of the present study was to detect neopterin concentrations in human tear samples and to evaluate its potential correlation with serum neopterin levels.
Baydar Terken, Kemer Ozlem Evren, Kilicarslan Bilge, Cardak Aziz, Girgin Gözde   +4 more
doaj   +1 more source

Serum Neopterin and Procalcitonin Levels in Relationship with Pediatric Burn Wound Infections [PDF]

, 2016
Infection and septic complications in burn patients can be monitored by procalcitonin (PCT) and neopterin plasma values. The aim of the study was to investigate serum neopterin and PCT levels with WBC (white blood cell) and CRP (C-reactive protein ...
Aslan, Mustafa, Dinc, Oyku, Ergin, Sevgi, Ersin, Idris, Habip, Zafer, Kocazeybek, Bekir, Kuvat, Nuray, Pilanci, Ozgur, Saribas, Suat, Sirekbasan, Serhat, Yuksel, Pelin   +10 more
core   +1 more source

Neopterin and 7,8-dihydroneopterin are generated within atherosclerotic plaques

Pteridines, 2015
Plasma neopterin correlates with the level of cardiovascular disease. Neopterin is the oxidation product of 7,8-dihydroneopterin, which is released by γ-interferon-stimulated macrophages. 7,8-Dihydroneopterin is a potent antioxidant, which inhibits lipid
Janmale Tejraj, Genet Rebecca, Crone Elizabeth, Flavall Elizabeth, Firth Carol, Pirker John, Roake Justin A., Gieseg Steven P.   +7 more
doaj   +1 more source

The relationship between plasma level of indoleamine 2,3-dioxygenase and neopterin in patients with depression

Psychiatry and Clinical Psychopharmacology, 2021
Objective: Preliminary results of the study that intended to compare serum indoleamine 2,3-dioxygenase (IDO) and neopterin levels in patients with major depression and the healthy control group is presented.
Adem Balıkcı, Murat Erdem, Abdullah Bolu, Tuncer Çaycı, Emre Aydemir, A. Gazi Ünlü, Emin Özgür Akgül   +6 more
doaj  

ATAD3 duplications bridge mitochondrial diseases and Aicardi–Goutières syndrome

Developmental Medicine &Child Neurology, Volume 68, Issue 2, Page 287-294, February 2026.
ATAD3 locus duplications cause a severe neonatal mitochondrial disorder with neuroimaging features resembling interferonopathies, and suggest a mitochondrial nucleic acid‐triggered interferon response. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16446 Abstract A recurrent 68‐kb heterozygous duplication of the ATAD3 locus ...
Pauline Planté‐Bordeneuve, Claire‐Marine Bérat, Sylvain Hanein, Cyril Gitiaux, ATAD3 Study Group, Julie Steffann, Isabelle Desguerre, Agnès Rötig, Nathalie Boddaert, Giulia Barcia, Brian Sperelakis‐Beedham, Zahra Assouline, Marie‐Thérèse Abi‐Warde, Rukhshona Abdullazoda, Agnès Guichet, Céline Bris, Aurélien Caux, Marlène Rio, Jérémy Bertrand, Pauline Gaignard, Alice Lepelley, Arnold Munnich, Manuel Schiff, Isabelle Desguerre, Agnès Rötig, Nathalie Boddaert, Giulia Barcia   +26 more
wiley   +1 more source

Effect of Neopterin on the Hematopoietic System

Pteridines, 2009
Neopterin is produced by monocytes and is a useful biomarker for inflammation. We recently found that neopterin is biologically active against hematopoiesis during inflammatory processes.
Tsuboi Isao, Aizawa Shin
doaj   +1 more source

Mediators of leukocyte yctivation play a role in disseminated intravascular coagulation during orthotopic liver transplantation [PDF]

, 1994
Leukocytes play an important role in the development of disseminated intravascular coagulation (DIC). In the reperfusion phase of OLT a DIC-like situation has been described and has been held responsible for the high blood loss during this phase.
Bechstein, W. O., Himmelreich, G., Jochum, Marianne, Machleidt, W., Neuhaus, P., Riess, H., Slama, K.-J.   +6 more
core  

Predictive Role of Hematological Biomarkers in Chronic Kidney Disease Progression

Journal of Clinical Laboratory Analysis, Volume 40, Issue 2, January 2026.
This retrospective study assessed the predictive value of hematological biomarkers in the progression and complications of chronic kidney disease (CKD) among 120 adult patients. Key findings revealed that declining hemoglobin and increasing red cell distribution width (RDW) and neutrophil‐to‐lymphocyte ratio (NLR) were significantly associated with ...
Collince Odiwuor Ogolla, Lucy W. Karani, Stanslaus Musyoki, Phidelis Maruti   +3 more
wiley   +1 more source