Results 31 to 40 of about 8,276 (115)
Dual Role of Exosomes in Parkinson's Disease: Adenine Exerts a Beneficial Effect
CNS Neuroscience &Therapeutics, Volume 31, Issue 4, April 2025.Exosomes derived from the blood of healthy rats have therapeutic effects on pathology in PD mice; conversely, exosomes released by PD model rats cause PD‐like pathological features in healthy mice. Adenine, which is enriched in healthy exosomes, plays a key role in PD pathology by activating the cAMP/PKA signaling pathway.
Lei Chen +6 more
wiley +1 more source
Cerebrospinal Fluid Concentrations of the Synaptic Marker Neurogranin in Neuro-HIV and Other Neurological Disorders. [PDF]
, 2019 Purpose of reviewThe aim of this study was to examine the synaptic biomarker neurogranin in cerebrospinal fluid (CSF) in different stages of HIV infection and in relation to what is known about CSF neurogranin in other neurodegenerative diseases.Recent ...
Blennow, Kaj +6 more
core +1 more source
Daily Complementary Feeding With Eggs Improves Fibroblast Growth Factor 21 in Infants
Maternal &Child Nutrition, Volume 21, Issue 2, April 2025.Complementary feeding with eggs led to a decrease in growth hormone resistance, as evidenced by improvements in FGF21 levels. However, baseline levels of FGF21 and I‐FAB were linked to increased growth faltering. ABSTRACT This secondary analysis of the Eggcel‐growth study investigated the effect of daily egg intake for 6 months in infants aged 6–9 ...
Regina Nakiranda +8 more
wiley +1 more source
Detection of neopterin in tear samples [PDF]
Pteridines, 2016 Abstract The main goal of the present study was to detect neopterin concentrations in human tear samples and to evaluate its potential correlation with serum neopterin levels. For this purpose, 20 systemically healthy volunteers were recruited, and both tear and serum samples were synchronically collected from each individual.
Ozlem Evren Kemer +4 more
openaire +3 more sources
Cancer Medicine, Volume 14, Issue 6, March 2025.ABSTRACT Background Differentiated thyroid cancer (DTC) is the primary subtype of thyroid cancer. Timely diagnosis and intervention are crucial for improving prognosis and survival. However, the effectiveness of existing serum markers is limited, necessitating the discovery of new biomarkers.
Qiang Miao +6 more
wiley +1 more source
Neopterin levels are independently associated with cardiac remodeling in patients with chronic heart failure [PDF]
, 2013 Neopterin, a marker of inflammation and monocyte activation, is found increased in patients with heart failure (HF). This study investigates whether neopterin levels correlate with left ventricular (LV) remodeling and brain natriuretic peptide (BNP), a ...
Belli, Oriana +10 more
core +1 more source
International Journal of Cancer, Volume 156, Issue 5, Page 930-942, 1 March 2025.What's New? Chronic inflammation can lead to cancer, particularly in the colon, and a glycoprotein associated with inflammation, lipocalin‐2 (LCN2), has been implicated in cancer progression. Here, using data from the European Prospective Investigation into Cancer and Nutrition cohort (EPIC), the authors show that higher levels of circulating LCN2 are ...
Robin Reichmann +29 more
wiley +1 more source
Inflammatory mediators, infection, sepsis, and multiorgan failure after severe trauma [PDF]
, 1992 The relation of (multiple) organ failure (OF) to the release of inflammatory mediators and the incidence of infection and sepsis was studied prospectively in 100 patients with multiple trauma (injury severity score=37).
Duswald, Karl-Heimo +7 more
core
Cytokine induction of neopterin production
Clinical and Experimental Immunology, 1991 SUMMARYThe pteridine neopterin is a marker of immunological activation and has been shown to be a useful marker of graft-versus-host disease (GVHD) in bone marrow transplant patients. High levels of both neopterin and interferon-gamma (IFN-γ) were produced in vitro during mixed lymphocyte responses, which may be considered to be a model of the primary ...
Joanna Sheldon +3 more
openaire +4 more sources
Faecal biomarkers in children with coeliac disease: A way forward?
Acta Paediatrica, Volume 114, Issue 3, Page 586-593, March 2025.Abstract Aim Novel markers to reflect the intestinal damage in coeliac disease are needed. We studied the potential of faecal and serum neopterin, and faecal myeloperoxidase, human β‐defensin‐2, and lipocalin‐2 in a case–control study. Methods Data were collected from medical records and a biobank including newly diagnosed coeliac disease patients ...
Laura Kivelä +4 more
wiley +1 more source