Results 1 to 10 of about 34,072 (291)

Factors associated with the recurrence of choroidal neovascularization in pathologic myopia

Frontiers in Medicine, 2022
PurposeTo investigate the factors associated with the recurrence of pathologic myopia choroidal neovascularization (PM-CNV).MethodsForty-eight eyes of 48 patients with PM-CNV treated with conbercept at least 6 months of follow-up were included ...
Ruixia Jing, Yuxia Bo, Lei Gao, Zhen Wang   +3 more
doaj   +3 more sources

Efficacy of Conbercept in the Treatment of Choroidal Neovascularization Secondary to Pathologic Myopia [PDF]

Frontiers in Medicine, 2021
Purpose: To observe the clinical efficacy of conbercept in the treatment of choroidal neovascularization (CNV) secondary to pathologic myopia.Methods: We used retrospective analysis of the clinical data of 20 patients (24 eyes) with pathologic myopia ...
Hui Lu, Tao Yue, Na Liu, Zuo-Fen Wang, Gai-Xia Zhai, Dong-Ming Mi, Jing Zhang, Shao-Peng Wang   +7 more
doaj   +4 more sources

Vascular endothelial growth factor and KIT expression in relation with microvascular density and tumor grade in supratentorial astrocytic tumors [PDF]

Acta Cirúrgica Brasileira, 2013
PURPOSE: To evaluate the relationship between microvascular density and the expression of vascular endothelial growth factor (VEGF) and KIT as possible markers of angiogenic stimulus in astrocytic tumors and correlate it with histopathological grading ...
Thaís Heinke, Kleber Simões do Espiríto Santo, Adhemar Longatto Filho, João Norberto Stavale   +3 more
doaj   +3 more sources

Topical Nanoemulsion of a Runt-related Transcription Factor 1 Inhibitor for the Treatment of Pathologic Ocular Angiogenesis

Ophthalmology Science, 2022
Purpose: To test the efficacy of runt-related transcription factor 1 (RUNX1) inhibition with topical nanoemulsion containing Ro5-3335 (eNano-Ro5) in experimental ocular neovascularization. Design: Preclinical experimental study.
Santiago Delgado-Tirado, MD, Lucia Gonzalez-Buendia, MD, Miranda An, BA, Dhanesh Amarnani, MS, Daniela Isaacs-Bernal, BSc, Hannah Whitmore, PhD, Said Arevalo-Alquichire, PhD, David Leyton-Cifuentes, BME, Jose M. Ruiz-Moreno, MD, PhD, Joseph F. Arboleda-Velasquez, MD, PhD, Leo A. Kim, MD, PhD   +10 more
doaj   +1 more source

Intussusceptive Vascular Remodeling Precedes Pathological Neovascularization [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2019
Objective— Pathological neovascularization is crucial for progression and morbidity of serious diseases such as cancer, diabetic retinopathy, and age-related macular degeneration. While mechanisms of ongoing pathological neovascularization have been extensively studied, the initiating pathological vascular remodeling (PVR ...
Anthony Mukwaya, Qiaolin Deng, Beatrice Bourghardt Peebo, Antje Biesemeier, Rickard Sandberg, Ulrich Schraermeyer, Claudia Gerri, Michele Marass, Julianna Kele, Anders Kvanta, Parviz Mammadzada, Luis del Peso, Luis del Peso, Daniel Ramsköld, Michael R. Taylor, Neil Lagali, Zaheer Ali, Camilla Hildesjö, Helder André, Anton Lennikov, Maria Ntzouni, Yihai Cao, Renhai Cao, John F. Steffensen, Lasse Jensen, Sarantis Giatrellis   +25 more
openaire   +8 more sources

Correlation between the expression of vegf and survival in osteosarcoma [PDF]

Acta Ortopédica Brasileira, 2014
Objective: To present a series of 50 consecutive patients with non-metastatic extremity osteosarcoma, and attempt to correlate expression of the vascular endothelial growth factor (VEGF) protein in biopsy tissue to their prognosis regarding overall ...
André Mathias Baptista, André Ferrari De França Camargo, Renée Zon Filippi, Cláudia Regina Gomes Cardim Mendes De Oliveira, Raymundo Soares De Azevedo Neto, Olavo Pires De Camargo   +5 more
doaj   +1 more source

ADAM9 Is Involved in Pathological Retinal Neovascularization [PDF]

Molecular and Cellular Biology, 2009
Pathological ocular neovascularization, caused by diabetic retinopathy, age-related macular degeneration, or retinopathy of prematurity, is a leading cause of blindness, yet much remains to be learned about its underlying causes. Here we used oxygen-induced retinopathy (OIR) and laser-induced choroidal neovascularization (CNV) to assess the ...
Peter A. Campochiaro, Steven L. Swendeman, Tsunehiko Yoshida, Carl P. Blobel, Carl P. Blobel, Victor H. Guaiquil, Sai H. Chavala   +6 more
openaire   +3 more sources

MicroRNA-18a-5p Administration Suppresses Retinal Neovascularization by Targeting FGF1 and HIF1A

Frontiers in Pharmacology, 2020
Pathologic ocular neovascularization commonly results in visual impairment or even blindness in numerous fundus diseases, including proliferative diabetic retinopathy (PDR), retinopathy of prematurity (ROP), and age-related macular degeneration (AMD ...
Ji-Tian Guan, Xin-Xin Li, De-Wei Peng, Wen-Meng Zhang, Jia Qu, Fan Lu, Fan Lu, Robert J. D’Amato, Robert J. D’Amato, Zai-Long Chi, Zai-Long Chi   +10 more
doaj   +1 more source

Successful Use of Conbercept to Treat Choroidal Neovascularization: A Case Report

Case Reports in Ophthalmology, 2022
Chronic urticaria is a dermatological condition characterized by the appearance of wheals or angioedema longer than 6 weeks. It could cause serious complications such as laryngeal edema, vasculitis, and diarrhea.
Jin Yang, Zheng Liu, Tao Liu
doaj   +1 more source

Interleukin-18 regulates pathological intraocular neovascularization [PDF]

Journal of Leukocyte Biology, 2007
AbstractRecently, the proinflammatory cytokine IL-18 has been shown to have a role in angiogenesis. This study aimed to elucidate its role in abnormal neovascularization (NV) in an oxygen-induced retinopathy (OIR) mouse model of the retinopathy seen in human premature newborns.
Yasuhiro Ikeda, Young Joon Jo, Yasuaki Hata, Yukio Sassa, Kuniaki Hijioka, Chikako Tsutsumi-Miyahara, Tatsuro Ishibashi, Shizuo Akira, Hong Qiao, Takeru Yoshimura, Koh Hei Sonoda   +10 more
openaire   +3 more sources