Pathological Investigation of Congenital Bicuspid Aortic Valve Stenosis, Compared with Atherosclerotic Tricuspid Aortic Valve Stenosis and Congenital Bicuspid Aortic Valve Regurgitation [PDF]
Congenital bicuspid aortic valve (CBAV) is the main cause of aortic stenosis (AS) in young adults. However, the histopathological features of AS in patients with CBAV have not been fully investigated.We examined specimens of aortic valve leaflets ...
A Mazzone+40 more
core +9 more sources
A Population-Based Ultra-Widefield Digital Image Grading Study for Age-Related Macular Degeneration-Like Lesions at the Peripheral Retina. [PDF]
Our understanding of the relevance of peripheral retinal abnormalities to disease in general and in age-related macular degeneration (AMD) in particular is limited by the lack of detailed peripheral imaging studies.
Bird, AC+6 more
core +1 more source
Laser Doppler holography of the anterior segment for blood flow imaging, eye tracking, and transparency assessment [PDF]
Laser Doppler holography (LDH) is a full-field blood flow imaging technique able to reveal human retinal and choroidal blood flow with high temporal resolution. We here report on using LDH in the anterior segment of the eye without making changes to the instrument.
arxiv +1 more source
IDO1 is an Integral Mediator of Inflammatory Neovascularization. [PDF]
The immune tolerogenic effects of IDO1 (indoleamine 2,3-dioxygenase 1) have been well documented and genetic studies in mice have clearly established the significance of IDO1 in tumor promotion.
Bravo-Nuevo, Arturo+6 more
core +3 more sources
Tendinopathy—from basic science to treatment [PDF]
Chronic tendon pathology (tendinopathy), although common, is difficult to treat. Tendons possess a highly organized fibrillar matrix, consisting of type I collagen and various 'minor' collagens, proteoglycans and glycoproteins.
A McCormick+69 more
core +1 more source
Corneal Angiogenesis: Etiologies, Complications, and Management [PDF]
A large subset of corneal pathologies involves the formation of new blood vessels, leading to compromised visual acuity. Additionally, neovascularization of the cornea worsens the prognosis of subsequent penetrating keratoplasty, keeping the patient in a
Feizi, Sepehr
core +2 more sources
Oxidative and Nitrosative Stress in Age-Related Macular Degeneration: A Review of Their Role in Different Stages of Disease [PDF]
Although the exact pathogenetic mechanisms leading to age-related macular degeneration (AMD) have not been clearly identified, oxidative damage in the retina and choroid due to an imbalance between local oxidants/anti-oxidant systems leading to chronic ...
De Cilla', Stefano+4 more
core +1 more source
Multi-Scale Convolutional Neural Network for Automated AMD Classification using Retinal OCT Images [PDF]
Age-related macular degeneration (AMD) is the most common cause of blindness in developed countries, especially in people over 60 years of age. The workload of specialists and the healthcare system in this field has increased in recent years mainly due to the prevalence of population aging worldwide and the chronic nature of AMD. Recent developments in
arxiv
Avastin in myopic choroidal neovascularisation: Is age the limit? [PDF]
published_or_final_versio
Li, KKW, Wong, D
core +1 more source
High-risk Pathologic Features Based on Presenting Findings in Advanced Intraocular Retinoblastoma A Multicenter, International Data-Sharing American Joint Committee on Cancer Study [PDF]
Purpose: To determine the value of clinical features for advanced intraocular retinoblastoma as defined by the eighth edition of the American Joint Committee on Cancer (AJCC) cT3 category and AJCC Ophthalmic Oncology Task Force (OOTF) Size Groups to ...
Amer Joint Comm Canc Ophthalmic On+5 more
core +1 more source