Results 151 to 160 of about 25,310 (262)

Indication‐Specific Dosing and Dose‐Evaluation Strategies in New Indications for Non‐Oncology Monoclonal Antibodies

The Journal of Clinical Pharmacology, EarlyView.
Abstract Compared to traditional small molecule drugs, monoclonal antibodies (mAbs) often display more complex pharmacokinetic (PK) and pharmacodynamic (PD) properties that may be impacted by disease‐specific factors. For mAbs in non‐oncology indications, where the same drug might be used for conditions involving different organ systems and/or having ...
Sherouk M. Tawfik, Fei Tang
wiley   +1 more source

Circulação colateral por vasa vasorum da artéria carótida interna ocluída – Breve relato de nove casos

Brazilian Neurosurgery, 2015
Augusto César de Jesus Santos, Rogério Zenóbio Darwich, Ana Cláudia de Assis Capanema, Fernanda Bretz Gomes dos Santos, Ricardo Penteado Lana, Romeu Vale Sant'anna, Rodrigo Menezes Xavier de Brito   +6 more
doaj   +1 more source

Imaging‐Based Molecular Characterization of Adult‐Type Diffuse Glioma Using Diffusion and Perfusion MRI in Pre‐ and Post‐Treatment Stage Considering Spatial and Temporal Heterogeneity

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Imaging‐based molecular characterization is important for identifying treatment targets in adult‐type diffuse gliomas. Purpose To assess isocitrate dehydrogenase (IDH) mutation and epidermal growth factor receptor (EGFR) amplification status in primary and recurrent gliomas using diffusion and perfusion MRI, addressing spatial and ...
Yun Hwa Roh, E‐Nae Cheong, Ji Eun Park, Yangsean Choi, Seung Chai Jung, Sang Woo Song, Young‐Hoon Kim, Chang‐Ki Hong, Jeong Hoon Kim, Ho Sung Kim   +9 more
wiley   +1 more source

Therapeutic Effects of Taurine and Histidine Supplementation in Retinal Diseases. [PDF]

Life (Basel)
Lee D, Smith LEH.
europepmc   +1 more source

Metformin reverses periodontal destruction caused by experimental periodontitis by inhibiting interleukin‐1β activity

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis is a destructive disease that affects periodontal tissue. While current research focuses on disease management, research on tissue repair remains limited. Metformin, a first‐line medication for diabetes treatment, has positive effects on bone health in nondiabetic patients.
Zhao Wang, Ju Han Song, Jung‐Woo Kim, Seung‐Hee Kwon, Xianyu Piao, Sin‐Hye Oh, Suk‐Gyun Park, Sun‐Hun Kim, Je‐Hwang Ryu, Ok‐Su Kim, Jeong‐Tae Koh   +10 more
wiley   +1 more source

Recent Insights into Roles of Hypoxia-Inducible Factors in Retinal Diseases. [PDF]

Int J Mol Sci
Lee D, Tomita Y, Miwa Y, Kunimi H, Nakai A, Shoda C, Negishi K, Kurihara T.   +7 more
europepmc   +1 more source

Cutting balloon atherotomy is associated with decreased stent utilization [PDF]

, 2003
Bach, Richard G., Casserly, Ivan P., Goldstein, Jeffrey A., Kurz, Howard I., Lasala, John M., Rinder, Morton R., Rogers, Jason H., Singh, Jasvindar, Taniuchi, Megumi   +8 more
core   +1 more source

Nanomaterial‐Integrated 3D Biofabricated Structures for Advanced Biomedical Applications

Macromolecular Materials and Engineering, EarlyView.
This review investigates the integration of nanomaterials into 3D biofabricated structures, highlighting the potential in tissue regeneration, wound healing, and cancer therapy. It discusses key techniques, including bioprinting and electrospinning, while addressing challenges such as biocompatibility, scalability, and regulatory barriers.
Mustafijur Rahman, Tanvir Mahady Dip, Md Golam Nur, Md Hasibul Hossain, Finn Snow, Nusrat Binta Hossain, Azadeh Mirabedini, Anita Quigley, Rajiv Padhye, Shadi Houshyar   +9 more
wiley   +1 more source

Two cases of therapeutic scleral lenses for KID syndrome. [PDF]

Am J Ophthalmol Case Rep
Gagliardi M, Asghari B.
europepmc   +1 more source

Serine supplementation suppresses hypoxia-induced pathological retinal angiogenesis. [PDF]

Theranostics
Yagi H, Qiu C, Zeng Y, Boeck M, Nian S, Chen CT, Harman JC, Kasai T, Lee J, Hirst V, Neilsen K, Wang C, Bora K, Maurya M, Rodrick T, Grumbine M, Yang Y, Hua Z, Sweet IR, Singh SA, Aikawa M, Chen J, Fu Z.   +22 more
europepmc   +1 more source