Results 161 to 170 of about 21,633 (255)

Creation of a rich vascular subcutaneous space for cell transplantation via injectable biological hydrogels. [PDF]

Sci Rep
Samy A, El-Sherbeny GA, Khater SM, Aamer HG, Abdelhameed MA, Refaie AF.   +5 more
europepmc   +1 more source

An update on the landscape of collagen bioactive fragments

The FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

The effect of amlodipin, a calcium channel blocker, on tendon healing: an experimental study in rat model of Achilles tendon injury. [PDF]

Eur J Trauma Emerg Surg
Karapinar SE, Duvarci UC, Tunc S, Sarıısık UU, Topcu OF, Dincer R, Cepni SK, Yonet AG, Armagan I, Imeci OB, Asci H.   +10 more
europepmc   +1 more source

ADAM17 and its proteolytic targets in disease pathogenesis

The FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

Secretome Profiling of Young Multipotent Stem Cells Reveals Angiogenic and Immunomodulatory Mechanisms Supporting Aged Neuromuscular Health. [PDF]

Aging Cell
Thompson SD, Rugel CL, Haller MR, Curtin JL, Dayanidhi S, Lavasani M.   +5 more
europepmc   +1 more source

Vaginal Microbiota and Ovarian Cancer: A New Frontier in Immunomodulation and Diagnosis

Immunology, EarlyView.
Microbial imbalance, dysbiosis, plays a role in ovarian carcinogenesis by interacting with the immune system and altering inflammatory pathways, notably Th17 pathways. In contrast, eubiosis, characterised by Lactobacillus dominance, protects against infections and maintains hormone metabolism.
Wafa Babay, Mariem Garci, Ahmed Baligh Laaribi, Nabil Mathlouthi, Imene Ouzari   +4 more
wiley   +1 more source

Challenge of Corneal Ulcer Healing: A Novel Conceptual Framework, the "Triad" of Corneal Ulcer Healing/Corneal Neovascularization/Intraocular Pressure, and Avascular Tendon Healing, for Evaluation of Corneal Ulcer Therapy, Therapy of Neovascularization, Glaucoma Therapy, and Pentadecapeptide BPC 157 Efficacy. [PDF]

Pharmaceuticals (Basel)
Masnec S, Kokot A, Kralj T, Zlatar M, Loncaric K, Sablic M, Kalauz M, Beslic I, Oroz K, Mrvelj B, Beketic Oreskovic L, Oreskovic I, Strbe S, Staresinic B, Slivsek G, Boban Blagaic A, Seiwerth S, Skrtic A, Sikiric P.   +18 more
europepmc   +1 more source

LIN28A blocks the EndMT process of high glucose‐induced HRMECs by stabilizing SIRT6 mRNA

Journal of Diabetes Investigation, EarlyView.
LIN28A promotes mRNA stability of SIRT6 to activate the AMPK signaling, thereby inhibiting the EndMT process induced by HG in HRMECs. ABSTRACT Background Diabetic retinopathy (DR) is a microvascular condition resulting from microangiopathy, causing gradual retinal damage and potential blindness.
Xueying Wang, Zixu Huang, Xiaohui Kuang, Yali Nan, Zhiwen Zhang, Zongming Song   +5 more
wiley   +1 more source

Alamandine inhibits pathological retinal neovascularization by targeting the MrgD-mediated HIF-1α/VEGF pathway. [PDF]

J Zhejiang Univ Sci B
Zhao K, Jiang Y, Huang W, Mao Y, Chen Y, Li P, Yang C.   +6 more
europepmc   +1 more source

Venous retinal flow reperfusion mechanisms following radial optic neurotomy with adjunctive intraocular triamcinolone in central retinal vein occlusion [PDF]

, 2009
Pina Fortunato, Liliana Pollazzi, Maurizio Baroni, Attilio Evangelisti, Agostino La Torre, The Eye Disease Case-Control Study Group, EZ Rath, SS Hayreh, SS Hayreh, WR Green, EM Opremcak, EM Opremcak, The Central Vein Occlusion Study Group, The Central Vein Occlusion Study Group N report, The Central Vein Occlusion Study Group, JB Jonas, The Central Vein Occlusion Study Group M Report, L Laatikainen, A Glacet-Bernard, LL Hansen, S Wolf, EM Opremcak, J Garcia-Arumi, PB Greenberg, CH Park, MS Ip, FC DeCroos, MS Mandelcorn, K Takahashi   +28 more
core   +1 more source