Results 171 to 180 of about 25,310 (262)

Deep learning (DL)‐based advancements in prostate cancer imaging: Artificial intelligence (AI)‐based segmentation of 68Ga‐PSMSA PET for tumor volume assessment

open access: yesPrecision Radiation Oncology, EarlyView.
This review highlights the use of 68Ga‐PSMA PET in prostate cancer (PC) for tumor volume quantification, crucial for staging, treatment planning, and prognosis. Traditional manual segmentation methods are time‐consuming and variable, while AI‐based segmentation techniques, particularly deep learning models like convolutional neural networks, offer ...
Sharjeel Usmani   +6 more
wiley   +1 more source

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

open access: yesSmall, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai   +5 more
wiley   +1 more source

Emerging clinical evidence of a dual role for Ang-2 and VEGF-A blockade with faricimab in retinal diseases. [PDF]

open access: yesGraefes Arch Clin Exp Ophthalmol
Chaudhary V   +12 more
europepmc   +1 more source

Synergistic Effect of Prolonged Oxygenation and Reactive Oxygen Species Scavenging on Diabetic Wound Healing Using an Injectable Thermoresponsive Hydrogel

open access: yesSmall, EarlyView.
The oxygen‐generating and reactive oxygen species‐scavenging hydrogel (ORH) exhibits thermoresponsive gelation and incorporates oxygen‐generating microspheres(OGMs) and chitosan‐catalase complexes(CSCATs) via hydrophobic and ionic interactions. Upon injection into irregular wound sites, ORH forms a gel at body temperature and sustains the release of ...
Jiyeon Lee   +3 more
wiley   +1 more source

Hypoxia-Dependent Upregulation of VEGF Relies on β3-Adrenoceptor Signaling in Human Retinal Endothelial and Müller Cells. [PDF]

open access: yesInt J Mol Sci
Lucchesi M   +6 more
europepmc   +1 more source

Frog‐Derived Neuroregenerative‐Peptide‐Reinforced Bioactive Hydrogels with Injectability, Thermosensitivity, and Enhanced Neurotrophic Function for Repairing Central Nervous Injuries

open access: yesSmall Structures, EarlyView.
Herein, the reinforcement of bioactive hydrogels with frog‐derived neuroregenerative peptide (FRNP) is presented to create multifunctional materials with injectability, thermosensitivity, and neurorepair capabilities. The formation of a porous, dual‐network hydrogel structure, combined with the action of FRNP, promotes the proliferation, migration, and
Zhengang Sun   +9 more
wiley   +1 more source

The Biomaterial and Blood Clot Complex: A Crucial Early Environment for Osteo‐Coagulo‐Immunomodulation and the Advancement of Bone Biomaterials

open access: yesSmall Structures, EarlyView.
Various properties of bone biomaterials can modulate components of the blood clot (including the fibrin network, red blood cells, platelets, and the complement system) in vivo implantation, leading to the formation of a biomaterial–blood clot complex (BBCC) significantly impacting subsequent osteoimmunomodulation.
Zongpu Han   +11 more
wiley   +1 more source

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