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Restoring Physiologic Barriers Against Neovascular Invasion
2014Age-related macular degeneration remains to be a major cause of irreversible blindness in the world. In this disease, neovascularization plays an important role in disease burden and progression. Current therapies focus on inhibition of neovascularization through suppression of the extracellular VEGF pathway.
Cecinio C. Ronquillo +2 more
openaire +1 more source
Journal of the American College of Surgeons, 2004
Abstract Introduction: Increasing evidence suggests the importance of bone-marrow derived progenitor cells in angiogenesis. However, the exact role of the progenitor cells in hindlimb revascularization is unknown. In order to determine if endothelial progenitor cells are necessary for hindlimb revascularization, we used Id1+/−, Id3−/− mutant mouse ...
Yuki Sakai, Darren Schneider
openaire +1 more source
Abstract Introduction: Increasing evidence suggests the importance of bone-marrow derived progenitor cells in angiogenesis. However, the exact role of the progenitor cells in hindlimb revascularization is unknown. In order to determine if endothelial progenitor cells are necessary for hindlimb revascularization, we used Id1+/−, Id3−/− mutant mouse ...
Yuki Sakai, Darren Schneider
openaire +1 more source
Molecular Pharmacology, 2010
Vascular endothelial growth factor (VEGF) and inducible nitric-oxide synthase (iNOS) have been implicated in ischemia-induced retinal neovascularization. Retinal ischemia has been shown to induce VEGF and iNOS expression. It has been postulated that one of the crucial consequences of iNOS expression in the ischemic retina is the inhibition of ...
M, DeNiro +4 more
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Vascular endothelial growth factor (VEGF) and inducible nitric-oxide synthase (iNOS) have been implicated in ischemia-induced retinal neovascularization. Retinal ischemia has been shown to induce VEGF and iNOS expression. It has been postulated that one of the crucial consequences of iNOS expression in the ischemic retina is the inhibition of ...
M, DeNiro +4 more
openaire +2 more sources
Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma
Ca-A Cancer Journal for Clinicians, 2020Aaron J Grossberg +2 more
exaly
Oral complications of cancer and cancer therapy
Ca-A Cancer Journal for Clinicians, 2012Joel B Epstein +2 more
exaly

