Results 111 to 120 of about 182,326 (341)

Physiological conditions influencing regenerative potential of stem cells [PDF]

, 2016
Stem cells are being used in the treatment of cardivovascular diseases. Here, we review the physiologic and pathologic conditions that impact the regenerative potential of stem cells in the treatment of cardiovascular diseases which include the influence
Avitabile, Daniele, De Falco, Elena, Gambini, Elisa, Spaltro, Gabriella   +3 more
core   +1 more source

Biomimetic Cell Membrane‐Coated Scaffolds for Enhanced Tissue Regeneration

Advanced Materials, EarlyView.
This review examines the development and use of cell membrane‐coated scaffolds in tissue engineering. Bioinspired phospholipid and glycocalyx coatings enhance anti‐fouling, anti‐thrombogenic, and selective molecular recognition properties. Native cell membrane coatings further support cell‐specific interactions, immune modulation, and reduced bacterial
Carmen Alvarez‐Lorenzo, Alejandro Ramirez‐Romero, Diana Peixoto, Maria Vivero‐Lopez, Isabel Rodríguez‐Moldes, Angel Concheiro   +5 more
wiley   +1 more source

High-Risk Corneal Graft Rejection in the Setting of Previous Corneal Herpes Simplex Virus (HSV)-1 Infection [PDF]

, 2016
Acknowledgments The authors thank M. Robertson and R. Fordyce for technical support during the duration of the study. The work performed in Aberdeen was supported by grant from Action Medical Research UK (SP4328; London, England, UK), NHS Grampian ...
Amescua, Guillermo, Forrester, John V., Hendricks, Robert L., Knickelbein, Jared E., Kuffova, Lucia, Medina, Carlos, Rowe, Alexander M., Yu, Tian   +7 more
core   +1 more source

3D Printing for Neural Repair: Bridging the Gap in Regenerative Medicine

Advanced Materials, EarlyView.
This perspective article discusses how 3D bioprinting is advancing the development of neural tissue models and implants. It highlights recent progress in fabricating complex, multicellular neural constructs, examines current technical barriers, and outlines future applications in disease modeling, neurotoxicity testing, and regenerative therapies ...
Mitchell St Clair‐Glover, Zhilian Yue, Mirella Dottori   +2 more
wiley   +1 more source

Zinc‐Coordinated Trienzyme Nanogel Cascade Therapy for Accelerated Post‐Pancreatectomy Cutaneous Wound Healing

Advanced Materials, EarlyView.
A zinc‐coordinated nanogel assembly is reported that co‐delivers three enzymes to regulate glucose, oxidative stress, and oxygen levels. This system mimics natural enzyme cascades to reprogram the wound environment after pancreatectomy. In a post‐pancreatectomy mouse model, it accelerates healing by reducing infection, promoting blood vessel growth ...
Yedong Ma, Chengke Xie, Chengyu Liao, Binting Huang, Siqi Liu, Junhua Kong, Xiaotong Fan, Zibiao Li, Shi Chen, Chaobin He   +9 more
wiley   +1 more source

Matrix Metalloproteinases and Glaucoma Treatment. [PDF]

, 2020
Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that degrade extracellular matrix (ECM) components such as collagen and have important roles in multiple biological processes, including development and tissue remodeling, both in ...
Dibas, Mohammed, Robinson, Michael R, Stamer, W Daniel, Weinreb, Robert N   +3 more
core  

Multimodal Platforms for Light‐Mediated Organic Bioelectronics

Advanced Materials Interfaces, EarlyView.
Optobioelectronic devices are paving the way for different types of interfacing with cells, in addition to classical electrical interfacing. Here, a future perspective for research in this field is discussed, in which different classes of light‐responsive materials are combined to create a highly dynamic interface that truly integrates with biological ...
Giovanna Gentile, Mehdi Ravandeh, Luisa Petti, Francesca D'Elia, Francesca Santoro   +4 more
wiley   +1 more source

Vascular Morphogenesis in the Context of Inflammation: Self-Organization in a Fibrin-Based 3D Culture System

Frontiers in Physiology, 2018
Introduction: New vessel formation requires a continuous and tightly regulated interplay between endothelial cells with cells of the perivascular microenvironment supported by mechanic-physical and chemical cues from the extracellular matrix.Aim: Here we
Beate M. Rüger, Tanja Buchacher, Alexander Giurea, Bernd Kubista, Michael B. Fischer, Michael B. Fischer, Johannes M. Breuss   +6 more
doaj   +1 more source

Nanoinjection Platform for Drug Delivery in Breast Cancer Therapeutics

Advanced Materials Interfaces, EarlyView.
A schematic shows Nanoarchaeosomes loaded with doxorubicin (NAD) delivered via silicon nanotubes (SiNTs) into MCF‐7 cells, triggering apoptosis and necrosis. Released doxorubicin generates ROS, disrupts mitochondria, and intercalates DNA. This dual‐action nanoinjection enhances cytotoxicity and improves breast cancer therapy efficacy.
Kaviya Vijayalakshmi Babunagappan, Subastri Ariraman, Jann Harberts, Vimalraj Selvaraj, Mukilarasi Bedatham, Narendran Sekar, Nicolas H Voelcker, Roey Elnathan, Swathi Sudhakar   +8 more
wiley   +1 more source

Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy

Advanced Robotics Research, EarlyView.
Robotic materials are playing an increasingly vital role in enabling sensing and actuation at small scales. This perspective highlights recent advances in magnetic materials and magnetically actuated devices for wireless sensing, actuation, and energy harvesting toward implantable robotic systems for closed‐loop therapy.
Yusheng Wang, Ruijian Ge, Xiaoguang Dong
wiley   +1 more source