Results 171 to 180 of about 182,326 (341)

Establishment of a novel alloxan‐induced rabbit model exhibiting unique diabetic retinal neuropathy features assessed via ERG + VEP

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Study workflow. Neuroretinal changes were observed in alloxan‐induced diabetic rabbits, while the retinal vasculature remained unaffected, indicating the successful establishment of a diabetic neuroretinal model. Abstract Background Diabetic retinal neuropathy (DRN) leads to significant visual impairment; however, no existing animal model fully ...
Xinlu Li   +9 more
wiley   +1 more source

Editorial: New insight into the diagnosis and treatment of age-related macular degeneration

open access: yesFrontiers in Medicine, 2022
Andrea Servillo   +5 more
doaj   +1 more source

Novel Extraluminal silicone tracheal stent: Development and evaluation in a rabbit model of tracheomalacia

open access: yesAnimal Models and Experimental Medicine, EarlyView.
A novel extraluminal silicone stent was developed and applied in a rabbit model of tracheomalacia. The stent effectively maintained airway patency and minimized tissue reaction without causing cartilage damage. This approach may offer a safe and effective alternative for treating tracheal collapse in small animals.
Yoon‐Hee Ryu   +6 more
wiley   +1 more source

Comparison of osseointegration in piezoimplants versus cylindrical implants [PDF]

open access: yes, 2019
BACKGROUND: Dental implants have been successful for the restoration of edentulous areas, but current techniques are inadequate in areas lacking sufficient bone volume. Piezoelectric surgery has shown encouraging effects on both osseous healing.
Fujinaka, Trevor
core  

The Natural History of Idiopathic Subfoveal Choroidal Neovascularization

open access: hybrid, 1995
Allen C. Ho   +3 more
openalex   +1 more source

Insight into pericytes in glioblastoma angiogenesis: In vivo tracking by two‐photon microscopy and proteomic profiling

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Based on the inducible pericyte ablation model, we discovered that Pdgfrb+ pericytes regulate glioblastoma (GBM) growth. Using the pericyte lineage tracing model, we revealed their dynamic behavior during GBM angiogenesis. Proteomic analysis combined with pericyte RNA analysis based on human single‐cell data demonstrated cross‐species conserved ...
Qinghong Wang   +5 more
wiley   +1 more source

Mass spectrometry in ocular drug research

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo   +6 more
wiley   +1 more source

Irisin‐Loaded Dissolving Microneedles Promote Rapid Wound Healing

open access: yesAdvanced NanoBiomed Research, EarlyView.
Schematic of effective wound healing facilitated by water‐degradable microneedles loaded with irisin that enhance irisin penetration, fibroblast migration, differentiation, and extracellular matrix synthesis at the wound site. Irisin, an exercise‐induced myokine with anti‐inflammatory and regenerative activity, is incorporated into dissolving poly ...
Yu‐Chi Pan   +6 more
wiley   +1 more source

Progress in Biomimetic Microdevices for Anticancer Drug Screening and their Potential for Enhancing In Vivo Efficacy

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo   +2 more
wiley   +1 more source

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