Results 71 to 80 of about 175,739 (194)

Inhibition of retinopathy of prematurity in rat by intravitreal injection of sorafenib [PDF]

International Journal of Ophthalmology, 2014
AIM:To investigate the effect of intravitreal injection administered sorafenib, a multikinase inhibitor, in a rat model of oxygen-induced retinopathy (OIR).METHODS:Seven-day-old Sprague-Dawley rats (n=144) were randomly assigned to six groups.
Li-Li Tian, Bing Ren, Xiao-Wei Gao, Ying Luo, Yan Cai, Kun Zhou, An-Jie Du, Yong Zhao   +7 more
doaj   +1 more source

Reconstituted high-density lipoproteins promote wound repair and blood flow recovery in response to ischemia in aged mice [PDF]

, 2016
Background: The average population age is increasing and the incidence of age-related vascular complications is rising in parallel. Impaired wound healing and disordered ischemia-mediated angiogenesis are key contributors to age-impaired vascular ...
Bursill, Christina A., Lam, Yuen Ting, Ng, Martin K. C., Ridiandries, Anisyah, Robertson, Stacy, Tan, Joanne T. M., Tsatralis, Tania, Vanags, Laura Z.   +7 more
core   +2 more sources

Effect of periocular injection of celecoxib and propranolol on ocular level of vascular endothelial growth factor in a diabetic mouse model [PDF]

International Journal of Ophthalmology, 2016
AIM: To investigate the effects of periocular injection of propranolol and celecoxib on ocular levels of vascular endothelial growth factor (VEGF) in a diabetic mouse model. METHODS: Forty 4-6wk BALB-C male mice weighing 20-25 g were used.
Saman Nassiri, Gholamreza Houshmand, Mostafa Feghhi, Alireza Kheirollah, Mohammad Bahadoram, Nariman Nassiri   +5 more
doaj   +1 more source

Controlled Delivery of Sdf-1 Alpha and Igf-1: Cxcr4(+) Cell Recruitment and Functional Skeletal Muscle Recovery [PDF]

, 2015
Therapeutic delivery of regeneration-promoting biological factors directly to the site of injury has demonstrated its efficacy in various injury models.
Farrar, Roger P., Hammers, David W., Hsieh, Pei-Ling, Merscham-Banda, Melissa, Pham, Chantal B., Rybalko, Viktoriya Y., Suggs, Laura J.   +6 more
core   +1 more source

Photodynamic therapy for neovascular age-related macular degeneration

Philippine Journal of Ophthalmology, 2005
Background: In neovascular age-related macular degeneration (ARMD) new vessels grow under the retina, distorting vision and leading to scarring. This is exacerbated if the blood vessels leak.
Richard P.L. Wormald, MA, MB, BCh, MSc, FRCS, FRCOphth, Jennifer R Evans, PhD, Katherine S Henshaw, Liam L Smeeth, MD   +3 more
doaj  

Pathophysiology of placentation abnormalities in pregnancy-induced hypertension

Vascular Health and Risk Management, 2008
Mitsuko Furuya1, Junji Ishida2,3, Ichiro Aoki1, Akiyoshi Fukamizu2,31Department of Pathology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan; 2Graduate School of Life and Environmental Sciences; 3Center for Tsukuba ...
Mitsuko Furuya, Junji Ishida, Ichiro Aoki, Akiyoshi Fukamizu   +3 more
doaj  

To branch or to expand?

eLife, 2016
Oscillating protein signals control the branching and expansion of blood vessels.
Esther M Bridges, Adrian L Harris
doaj   +1 more source

Computer simulation of glioma growth and morphology [PDF]

, 2007
Despite major advances in the study of glioma, the quantitative links between intra-tumor molecular/cellular properties, clinically observable properties such as morphology, and critical tumor behaviors such as growth and invasiveness remain unclear ...
Adam, Ambrosi, Ambrosi, Anderson, Anderson, Anderson, Anderson, Araujo, Augustin, Bartels, Bello, Bellomo, Berger, Bernsen, Bernsen, Boegler, Brandt, Bullitt, Byrne, Byrne, Byrne, Byrne, Cai, Carmeliet, Chaplain, Chaplain, Chaplain, Chaplain, Condeelis, Cristini, Cristini, Cursiefen, DeJaeger, Derycke, Eble, Elaine L. Bearer, Ellis, Elvin, Fallenstein, Frieboes, Friedl, Friedl, Friedl, Friedman, Garcke, Gatenby, Giese, Greenspan, Hayot, Helmlinger, Hermann B. Frieboes, Holash, Holash, Huang, Jacqmin, Jain, Jain, John S. Lowengrub, Keller, Khoshyomn, Kim, Kim, Kim, Kopfstein, Kuiper, Kumar, Kunkel, Lah, Lamszus, Lee, Leo, Less, Li, Li, Lockett, Lowengrub, Macklin, Macklin, McDougall, McLean, Naganuma, O'Connor, Ommaya, Padera, Page, Patan, Patan, Paul Macklin, Pennacchietti, Plank, Plank, Preusser, Ridley, Rofstad, Rubenstein, S. Wise, Sahai, Sanga, Seftor, Shweiki, Sierra, Sinek, Skinner, Steeg, Sun, Takano, Toker, Tysnes, Vajkoczy, van Kempen, Vittorio Cristini, Wise, Wolf, Wurzel, X. Zheng, Yamaguchi, Yin, Zheng   +117 more
core   +1 more source

Nanomedicine Approaches for Corneal Diseases

Journal of Functional Biomaterials, 2015
Corneal diseases are the third leading cause of blindness globally. Topical nonsteroidal anti-inflammatory drugs (NSAIDs), steroids, antibiotics and tissue transplantation are currently used to treat corneal pathological conditions.
Shyam S. Chaurasia, Rayne R. Lim, Rajamani Lakshminarayanan, Rajiv R. Mohan   +3 more
doaj   +1 more source

Enhanced Integrin α4β1-Mediated Adhesion Contributes to a Mobilization Defect of Endothelial Progenitor Cells in Diabetes. [PDF]

, 2016
Diabetes is associated with a deficit of circulating endothelial progenitor cells (EPCs), which has been attributed to their defective mobilization from the bone marrow.
Abplanalp, Wesley T, Bhatnagar, Aruni, Cantor, Joseph M, Conklin, Daniel J, Ginsberg, Mark H, O'Toole, Timothy E, Wysoczynski, Marcin   +6 more
core   +2 more sources