Matrix Metalloproteinases and Glaucoma Treatment. [PDF]
, 2020 Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that degrade extracellular matrix (ECM) components such as collagen and have important roles in multiple biological processes, including development and tissue remodeling, both in ...
Dibas, Mohammed +3 more
core
High-Risk Corneal Graft Rejection in the Setting of Previous Corneal Herpes Simplex Virus (HSV)-1 Infection [PDF]
, 2016 Acknowledgments The authors thank M. Robertson and R. Fordyce for technical support during the duration of the study. The work performed in Aberdeen was supported by grant from Action Medical Research UK (SP4328; London, England, UK), NHS Grampian ...
Amescua, Guillermo +7 more
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Frontiers in Oncology, 2020 Neovascularization is required in high-grade glioma (HGG). The objective of this study was to explore neovascularization-related genes and their corresponding MRI biomarkers during the early-growth stage of HGG.
Wei Xue +18 more
doaj +1 more source
Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation. [PDF]
, 2019 Blood vessels in the central nervous system (CNS) develop unique features, but the contribution of CNS neurons to regulating those features is not fully understood. We report that inhibiting spontaneous cholinergic activity or reducing starburst amacrine
Angelopoulos, CM +8 more
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E2F1 Suppresses Oxidative Metabolism and Endothelial Differentiation of Bone Marrow Progenitor Cells [PDF]
, 2018 RATIONALE: The majority of current cardiovascular cell therapy trials use bone marrow progenitor cells (BM PCs) and achieve only modest efficacy; the limited potential of these cells to differentiate into endothelial-lineage cells is one of the major ...
Boriboun, Chan +17 more
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Neovascularization in Purtscher's retinopathy
Clinical Ophthalmology, 2011 We report a case of neovascularization secondary to Purtscher's retinopathy that showed minimal improvement with photocoagulation treatment. A 14-year-old boy with a history of cerebellar medulloblastoma presented with blurry vision and floaters after being struck by a motor vehicle while riding his bike.
Chan, Annie +2 more
openaire +3 more sources
The ratio of VEGF/PEDF expression in bone marrow mesenchymal stem cells regulates neovascularization [PDF]
, 2011 Angiogenesis, or neovascularization, is a finely balanced process controlled by pro- and anti-angiogenic factors. Vascular endothelial growth factor (VEGF) is a major pro-angiogenic factor, whereas pigment epithelial-derived factor (PEDF) is the most ...
Crawford, Ross, Fan, Wei, Xiao, Yin
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Peptide Lv and Angiogenesis: A Newly Discovered Angiogenic Peptide
BiomedicinesPeptide Lv is a small endogenous secretory peptide with ~40 amino acids and is highly conserved among certain several species. While it was first discovered that it augments L-type voltage-gated calcium channels (LTCCs) in neurons, thus it was named ...
Dylan L. Pham +3 more
doaj +1 more source
Thrombospondin 1 (THBS1) Promotes Follicular Angiogenesis, Luteinization, and Ovulation in Primates
Frontiers in Endocrinology, 2019 Angiogenesis is essential to both ovulation and the formation of the corpus luteum. The thrombospondin (THBS) family of glycoproteins plays diverse roles in regulation of angiogenesis, but the role of these vascular regulators in ovulation and ...
Hannah R. Bender +4 more
doaj +1 more source
Physiological conditions influencing regenerative potential of stem cells [PDF]
, 2016 Stem cells are being used in the treatment of cardivovascular diseases. Here, we review the physiologic and pathologic conditions that impact the regenerative potential of stem cells in the treatment of cardiovascular diseases which include the influence
Avitabile, Daniele +3 more
core +1 more source