Results 1 to 10 of about 367,294 (339)
Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis [PDF]
, 2017 IgA nephropathy (IgAN) is the most prevalent among primary glomerular diseases worldwide. Although our understanding of IgAN has advanced significantly, its underlying biology and potential drug targets are still unexplored.
Cisek, Katryna +11 more
core +8 more sources
Loss of Farnesoid X receptor (FXR) accelerates dysregulated glucose and renal injury in db/db mice [PDF]
PeerJ, 2023 Background End-stage renal disease is primarily caused by diabetic kidney disease (DKD). The Farnesoid X receptor (FXR), a member of the nuclear receptor superfamily, has anti-inflammatory, lipid-lowering and hypoglycemic properties.
Yuxiang Qiu +6 more
doaj +2 more sources
Coagulation Function and Type 2 Diabetic Kidney Disease: A Real-World Observational Study
Journal of Diabetes Research, 2023 Objectives. Type 2 diabetic kidney disease (DKD), a chronic microvascular complication of diabetes, may exhibit a complex interrelation with coagulation function.
Meng-chao Liu +11 more
doaj +1 more source
lncRNA MALAT1 Promotes Diabetic Nephropathy Progression via miR-15b-5p/TLR4 Signaling Axis
Journal of Immunology Research, 2022 Objective. The long noncoding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) are closely associated with the pathogenesis of diabetic nephropathy (DN). But a complete mechanism for MALAT1 in DN has yet to be identified.
Zijun Yang +3 more
doaj +1 more source
Journal of Diabetes Research, 2022 Shenlian (SL) decoction is a herbal formula composed of Coptis and ginseng, of which berberine and ginsenoside are the main constituents. Even though SL decoction is widely used in treating diabetes in China, the mechanism of its antidiabetes function ...
Rui-xi Sun +11 more
doaj +1 more source
Journal of the Royal College of Physicians of London, 1997 link_to_subscribed_fulltext
Simon C Satchell, Peter W Mathieson
openaire +4 more sources
Renal Failure, 2021 Purpose To identify the clinical characteristics, histopathological features, and prognosis of kidney disease in a large cohort of elderly patients from Northeast China. Methods We retrospectively analyzed the renal disease spectrum in 7,122 patients who
Ping Nie +7 more
doaj +1 more source
BMC Nephrology, 2022 Objective To explore the technical specifications and clinical outcomes of thrombosed aneurysmal haemodialysis arteriovenous fistula (AVF) treated with ultrasound-guided percutaneous transluminal angioplasty combined with minimal aneurysmotomy.
Wei Liu +8 more
doaj +1 more source
Biological Pathways and Potential Targets for Prevention and Therapy of Chronic Allograft Nephropathy [PDF]
, 2014 Renal transplantation (RT) is the best option for patients with end-stage renal disease, but the half-life is limited to a decade due to progressive deterioration of renal function and transplant failure from chronic allograft nephropathy (CAN), which is
Haylor, John, Shrestha, Badri Man
core +6 more sources
Nutrition & Diabetes, 2022 Objective We investigated the correlation between zinc levels and Nrf2 expression and potential effects on the clinicopathology of patients with diabetic nephropathy (DN).
Ping Nie +7 more
doaj +1 more source