Results 181 to 190 of about 15,009 (224)

Nephroprotective Effect of ACE Inhibitors

Drugs, 1993
In most cases of renal disease, progression of renal failure occurs via nonspecific mechanisms that can be dissociated from the primary cause of renal damage. Progression of disease is accompanied by glomerulosclerosis and tubulointerstitial fibrosis.
S, Orth, M, Nowicki, A, Wiecek, E, Ritz
openaire   +2 more sources

Nephroprotective action of sirtuin 1 (SIRT1)

Journal of Physiology and Biochemistry, 2013
Sirtuins, silent information regulator 2 (Sir 2) proteins, belong to the family of NAD(+)-dependent enzymes with deacetylase or mono-ADP-ribosyltransferase activity. These enzymes are responsible for processes of DNA repair or recombination, chromosomal stability and gene transcription.
Dorota, Polak-Jonkisz, Krystyna, Laszki-Szcząchor, Leopold, Rehan, Witold, Pilecki, Henryk, Filipowski, Małgorzata, Sobieszczańska   +5 more
openaire   +2 more sources

Nephroprotection by Antihypertensive Agents

Journal of Cardiovascular Pharmacology, 1994
Arterial hypertension is one of the few factors confirmed to accelerate the development of renal failure. Conversely, several studies have documented that systematic reduction of the blood pressure slows the progression of renal failure. It is postulated that 24-h reduction of the blood pressure should be achieved, best controlled by ambulatory blood ...
openaire   +2 more sources

Wine, sirtuins and nephroprotection: Not only resveratrol

Medical Hypotheses, 2010
Resveratrol (RSV), a red wine component, and red wine itself exert cardio- and nephroprotective effects by modulating the Nitric Oxide system (NO). It has been shown that one of the main actions resulting from NO modulation is sirtuin regulation, especially SIRT-1 regulation.
Mannari C, Bertelli AA, Stiaccini G, GIOVANNINI, LUCA   +3 more
openaire   +4 more sources

Nephroprotection and iodinate contrast medias

Radiología (English Edition)
The incidence of post-contrast acute kidney injury (PC-AKI) is low with the new low- or iso-osmolar non-ionic iodinated contrast agents. The only proven form of prophylaxis for PC-AKI is hydration, preferably intravenous, although oral hydration is equally effective.
C, Sebastià, S, Falip, R, Crespo, E, Guillen, C, Nicolau, E, Poch, L, Oleaga   +6 more
openaire   +2 more sources

Nephroprotection with saxagliptin.

Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2015
The nephroprotective effect of the new anti-diabetic drugs acting on incretin system is suggested by preclinical studies. However, no study evaluating kidney effects of these drugs as primary outcome on the long term has been conducted in patients followed in diabetes centers.
Iazzetta, Nicolangelo, Garofalo, Carlo, Savino, Manuela, Sagliocca, Adelia, Santangelo, Sara, Pacilio, Mario, Liberti, Maria Elena, Camocardi, Andrea, Ambrosca, Camilla, MINUTOLO, Roberto, DE NICOLA, Luca, CONTE, Giuseppe   +11 more
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[Gliflozins: Proteinuria Control and Nephroprotection].

Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia
In recent years, the prevalence of chronic kidney disease (CKD) has significantly increased, with an estimated 843.6 million individuals affected in 2017 [1]. This rise is closely linked to the growing incidence of risk factors such as diabetes mellitus and obesity.
Barbuto, Simona, Catalano, Veronica, Pira, Marianna, Cianciolo, Giuseppe, Comai, Giorgia, Capelli, Irene, Tondolo, Francesco, Maritati, Federica, La Manna, Gaetano   +8 more
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Blood Pressure Control and Nephroprotection in Diabetes

The Journal of Clinical Pharmacology, 2004
Achievement of recommended levels of blood pressure as prescribed by guidelines (i.e., systolic blood pressure of < 130 mmHg in people with nephropathy secondary to type 2 diabetes) generally requires three or more different antihypertensive agents that have complementary modes of action.
Kevin, Abbott, Emad, Basta, George L, Bakris   +2 more
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Nephroprotective Effect of Bosentan in Diabetic Rats

Journal of Cardiovascular Pharmacology, 2003
Previous studies have suggested that endothelins could be involved in the pathogenesis of target organ damage in diabetes. The aim of this study was to evaluate the possible protective effect of Bosentan, an antagonist of endothelin receptor, on the kidney of diabetic rats.
COSENZI, ALESSANDRO, BERNOBICH E, TREVISAN R, MILUTINOVIC N, BORRI A, BELLINI G.   +5 more
openaire   +3 more sources

[New perspectives for bradykinin in nephroprotection].

Medecine sciences : M/S, 2007
Various diseases such as arterial hypertension, diabetes and obesity result in renal diseases which are often irreversible and resistant to currently available therapies. Beside the control of glycemia in diabetic patients, only the blockade of the renin-angiotensin system is effective in reducing the occurrence of glomerulosclerosis and its ...
Buléon, Marie, Mehrenberger, Marion, Pécher, Christiane, Praddaude, Françoise, Couture, Réjean, Tack, Ivan, Girolami, Jean-Pierre   +6 more
openaire   +2 more sources