Results 61 to 70 of about 15,009 (224)

Resveratrol inhibits the intracellular calcium increase and angiotensin/endothelin system activation induced by soluble uric acid in mesangial cells [PDF]

, 2014
Resveratrol (Resv) is natural polyphenol found in grapes. This study evaluated the protective effect of Resv against the effects of uric acid (UA) in immortalized human mesangial cells (ihMCs).
Albertoni, Guilherme Ambrozio, Schor, Nestor   +1 more
core   +3 more sources

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Assessment of hepatoprotective and nephroprotective effects of Vitis vinifera leaf extract on carbon tetrachloride induced toxicity in rats

Journal of Applied Pharmaceutical Research
Background: Vitis vinifera is known for its antimicrobial activity; however, the hepatoprotective activity of aqueous extracts of aerial parts has also been reported, but the nephroprotective and hepatoprotective activity of ethanolic extracts have not ...
Ashok Kumar, Pragi, Amit Sharma, Varun Kumar   +3 more
doaj   +1 more source

Contrast‐enhanced CT—Nephrotoxic or not? A critical review of propensity‐score‐adjusted studies

Journal of Internal Medicine, EarlyView.
Abstract Retrospective, propensity‐score‐adjusted (PSA) studies have indicated to practitioners in the field that contrast‐induced acute kidney injury (AKI) after contrast‐enhanced CT (CECT) is of minor importance or even non‐existent. This has led to controversies between clinicians demanding CECT not to miss any diagnoses and radiologists reluctant ...
Ulf Nyman, Jonas Björk, Mikael Hellström, Peter Leander, Per Liss, Gunnar Sterner, Torkel B. Brismar   +6 more
wiley   +1 more source

Nephroprotective activity of Boerhavia diffusa

International Journal of Pharmaceutical Chemistry and Analysis, 2022
Nephrotoxicity is one of the most common kidney disorders which occurs when the body is exposed to accumulation of drug or toxin and not able to excrete. A number of therapeutic drugs such as antibiotics, chemotherapeutic agents etc., can weaken the kidney function resulting in acute renal failure, chronic interstitial nephritis, impair the renal ...
openaire   +2 more sources

Evaluation of the hepatoprotective and nephroprotective properties of bael fruit extract against carbon tetrachloride-induced toxicity in rats

Journal of Applied Pharmaceutical Research
Background: Bael is well-known for its antibacterial properties. Aqueous fruit extracts have also been shown to have hepatoprotective properties; the nephroprotective and hepatoprotective properties of Ethanolic extracts have not yet been tested ...
Deepak Garg, Amit Sharma, Pragi, Varun Kumar   +3 more
doaj   +1 more source

Extract of Ferula foetida regel reverses gentamicin-induced nephrotoxicity in rats [PDF]

, 2013
Natural products and dietary components have earlier been proven as potential chemoprotective agents, and continuous efforts are in progress to search for such new products.
Aslam, Mohd, Azhar, M.U., Javaid, Raheela, Javaid, Rasikh, Javed, Kalim, Nizami, Qudsia   +5 more
core  

Effect of oral administration of ethanolic extract of Vitex negundo on thioacetamide-induced nephrotoxicity in rats [PDF]

, 2013
BACKGROUND: Oxidative stress due to abnormal induction of reactive oxygen species (ROS) molecules is believed to be involved in the etiology of many diseases.
Farkaad A Kadir, Mahmood A Abdulla, Normadiah M Kassim, Wageeh A Yehye   +3 more
core   +1 more source

Research Progress on Risk Factors for Acute Kidney Injury After Antibiotic‐Loaded Bone Cement Spacer Treatment for Periprosthetic Joint Infection

Orthopaedic Surgery, EarlyView.
During the two‐stage revision treatment of PJI patients, the use of ALCS may lead to the development of AKI, which could result in severe adverse outcomes. Despite the wide variation in the incidence of developing AKI reported in the literature, clinicians still need adequate attention, especially when confronting PJI patients who are elderly, obese ...
Lijun Cai, Xingxiao Pu, Yajie Chen, Guangtao Han, Qianhao Li, Qiuru Wang, Pengde Kang   +6 more
wiley   +1 more source

Nephroprotective Effects of Metformin in Diabetic Nephropathy

Journal of Cellular Physiology, 2016
Metformin, a well‐known anti‐diabetic agent, is very effective in lowering blood glucose in patients with type 2 diabetes with minimal side‐effects. Metformin is also being recommended in the treatment of obesity and polycystic ovary syndrome. Metformin elicits its therapeutic effects mainly via activation of AMP‐activated kinase (AMPK) pathway.
Ravindran, Sreenithya, Kuruvilla, Vinitha, Wilbur, Kerry, Munusamy, Shankar   +3 more
openaire   +4 more sources