ESC Heart Failure, EarlyView.Abstract In the 2021 European Society of Cardiology (ESC) heart failure (HF) guidelines, sodium–glucose cotransporter 2 (SGLT2) inhibitors were recommended for the prevention of HF in patients with type 2 diabetes mellitus (T2DM) and for the treatment of HF with reduced ejection fraction (HFrEF).
Marco Metra +25 more
wiley +1 more source
Presenilin-Dependent Transcriptional Control of the Aβ-Degrading Enzyme Neprilysin by Intracellular Domains of βAPP and APLP [PDF]
, 2005 Raphaëlle Pardossi‐Piquard +11 more
openalex +1 more source
Transcriptomic analysis of Ascaris suum larvae during their hepatopulmonary migration [PDF]
, 2012 Common roundworms are important intestinal nematodes of man (Ascaris lumbricoides) and pig (Ascaris suum). During the first stages of the infection, the larvae of these parasites undergo a hepatopulmonary migration.
Gasser, Robin +4 more
core +1 more source
ESC Heart Failure, EarlyView.Central Illustration caption: This analysis of vericiguat's treatment effect revealed no inter‐geographic region heterogeneity for the primary composite endpoint (time to HF‐related hospitalization or cardiovascular (CV) death or its components) (Left Panel).
Cynthia M. Westerhout +9 more
wiley +1 more source
The effect of angiotensin receptor neprilysin inhibitor, sacubitril/valsartan, on central nervous system amyloid-β concentrations and clearance in the cynomolgus monkey [PDF]
, 2017 Bateman, Randy J, et al,
core +2 more sources
Physical activity and beta-amyloid pathology in Alzheimer's disease [PDF]
, 2017 Alzheimer's disease (AD) is the most common type of dementia worldwide. Since curative treatment has not been established for AD yet and due to heavy financial and psychological costs of patients’ care, special attention has been paid to preventive ...
Baghaiee, Behrouz +4 more
core
951. Evaluation of HSV-Mediated Alzheimer Gene Therapy Vectors Using Novel Alzheimer Mouse Model: Applications of siRNA and Neprilysin Vectors to Adjust the Metabolic Imbalance of Aâ in Alzheimer's Disease [PDF]
, 2005 Chang-Sook Hong +3 more
openalex +1 more source
ESC Heart Failure, EarlyView.Using EndoWings™ and XDROP™, we developed a percutaneous minimally invasive technique for sequential circumferential alginate hydrogel injection into LV free mid‐wall. This human study assessed its safety/feasibility in HFrEF patients, with personalised biomechanical models.
Bo Wang +13 more
wiley +1 more source
Angiotensin receptor-neprilysin inhibitors in concurrent heart failure with reduced ejection fraction and kidney failure. [PDF]
ESC Heart FailAbstract Aims Angiotensin receptor‐neprilysin inhibitor (ARNI) therapy has demonstrated improved outcomes in heart failure with reduced ejection fraction (HFrEF). However, its benefits in patients with concomitant kidney failure undergoing replacement therapy remain uncertain. Methods and results Using the National Health Insurance Service database, we
Jung MH +8 more
europepmc +2 more sources
Successive Action of Meprin A and Neprilysin Catabolizes B-Type Natriuretic Peptide [PDF]
, 2007 Kristin Pankow +8 more
openalex +1 more source