Results 181 to 190 of about 25,082 (343)

Right ventricular global work efficiency: A reliable non‐invasive estimate of right ventricular contractility

ESC Heart Failure, EarlyView.
The figure illustrates the study design and key findings related to right ventricular myocardial work (RVMW) in heart failure with reduced ejection fraction (HFrEF) patients with and without pulmonary hypertension (PH). Patients were stratified into two groups: those with PH (n = 53) and those without PH (n = 49), as determined by right heart ...
Paolo Manca, Vincenzo Nuzzi, Alessandro Lucchino, Gerardo Rugiano, Massimiliano Mulè, Alessandra Carvelli, Stefano Cannata, Sergio Sciacca, Francesca Parisi, Sabato Sorrentino, Francesco Fulvio Faletra, Paolo C. Colombo, Manlio Gianni Cipriani   +12 more
wiley   +1 more source

HIV-1 Tat inhibits neprilysin and elevates amyloid β

, 2005
Hans Rempel, Lynn Pulliam
openalex   +1 more source

In vitro Pb exposure disturbs the balance between Aβ production and elimination: The role of AβPP and neprilysin [PDF]

, 2011
Hui Huang, Syed Waseem Bihaqi, Liuxin Cui, Nasser H. Zawia   +3 more
openalex   +1 more source

Pulmonary congestion relief by adding dapagliflozin to intravenous loop diuretic in acute heart failure patients

ESC Heart Failure, EarlyView.
Abstract Aims We aim to assess the efficacy of congestion relief and safety associated with adding SGLT2i (viz., dapagliflozin 10 mg) to intravenous loop diuretics within 24 h of hospital presentation in patients with acute heart failure (AHF). Methods and results A single‐centre open‐label clinical research study enrolled 98 patients admitted with an ...
Daniela Mocan, Maria Puschita, Diana Lungeanu, Adina Pop‐Moldovan, Luminita Pilat, Dan Darabantiu, Radu Jipa, Radu Ioan Lala   +7 more
wiley   +1 more source

Angiotensin receptor‐neprilysin inhibitors in concurrent heart failure with reduced ejection fraction and kidney failure

ESC Heart Failure, EarlyView.
Abstract Aims Angiotensin receptor‐neprilysin inhibitor (ARNI) therapy has demonstrated improved outcomes in heart failure with reduced ejection fraction (HFrEF). However, its benefits in patients with concomitant kidney failure undergoing replacement therapy remain uncertain. Methods and results Using the National Health Insurance Service database, we
Mi‐Hyang Jung, Dong‐Hyuk Cho, Jimi Choi, Mi‐Na Kim, Chan Joo Lee, Jung‐Woo Son, Yaeni Kim, Jong‐Chan Youn, Byung‐Su Yoo   +8 more
wiley   +1 more source

Machine learning approach to identify phenotypes in patients with ischaemic heart failure with reduced ejection fraction

European Journal of Heart Failure, EarlyView.
Summary of the machine learning clustering methodology and results of the study. Clusters are identified using machine learning approach in the learning set population evaluating specific combinations of multiple characteristics. Then identified clusters are predicted and tested in the learning set to evaluate their association with outcomes.
Luca Monzo, Emmanuel Bresso, Kenneth Dickstein, Bertram Pitt, John G.F. Cleland, Stefan D. Anker, Carolyn S.P. Lam, Mandeep R. Mehra, Dirk J. van Veldhuisen, Barry Greenberg, Faiez Zannad, Nicolas Girerd   +11 more
wiley   +1 more source

8532 Circulating Neprilysin in Pregnancy [PDF]

J Endocr Soc
Abstract Disclosure: A. Kulovic-Sissawo: None. E. Weiss: None. E. Jantscher-Krenn: None. U. Hiden: None. Background: In the complex nature of pregnancy, the female organism undergoes pivotal vascular and metabolic changes orchestrated by a tightly regulated interplay of bioactive regulatory molecules.
Kulovic-Sissawo, Azra, Weiss, Elisa, Jantscher-Krenn, Evelyn, Hiden, Ursula   +3 more
europepmc   +2 more sources

The risk of death according to left ventricular ejection fraction and right ventricular dilatation in 17 321 adults with heart failure from 40 high‐, middle‐ and low‐income countries – A Global Congestive Heart Failure (G‐CHF) study

European Journal of Heart Failure, EarlyView.
Abstract Aims The aim of this study was to describe the prognostic importance of left ventricular ejection fraction (LVEF) versus right ventricular (RV) dilatation and dysfunction in patients with heart failure (HF) from countries of different income levels. Methods and results We enrolled 17 321 participants with HF from 40 countries.
Darryl P. Leong, Philip G. Joseph, Hisham Dokainish, Stefan Störk, John V.V. McMurray, Lisa M. Mielniczuk, Sanjib Kumar Sharma, Andrés Orlandini, Kamilu M. Karaye, Antoni Bayes‐Genis, Tara McCready, Alex Grinvalds, Kumar Balasubramanian, Kelley R. Branch, Kristian Kragholm, Salim Yusuf, on behalf of the G‐CHF Investigators   +16 more
wiley   +1 more source

Enhanced Proteolytic Clearance of Plasma Aβ by Peripherally Administered Neprilysin Does Not Result in Reduced Levels of Brain Aβ in Mice [PDF]

, 2013
John R. Walker, Reynand Pacoma, James Watson, Weijia Ou, Juliano Alves, Daniel E. Mason, Eric C. Peters, Hugo D. Urbina, Gus Welzel, Alana Althage, Bo Liu, Tove Tuntland, Laura H. Jacobson, Jennifer L. Harris, Andrew M. Schumacher   +14 more
openalex   +1 more source

Cardiovascular magnetic resonance‐estimated pulmonary capillary wedge pressure, congestion markers, and effect of empagliflozin in patients with heart failure with reduced ejection fraction and dysglycaemia (SUGAR‐DM‐HF)

European Journal of Heart Failure, EarlyView.
Abstract Aims A cardiovascular magnetic resonance (CMR) approach to non‐invasively estimate left ventricular (LV) filling pressure was recently developed and shown to correlate with invasively measured pulmonary capillary wedge pressure (PCWP). We examined the association between CMR‐estimated PCWP (CMR‐PCWP) and other imaging and biomarker measures of
Joanna Osmanska, Kieran F. Docherty, Colin Berry, Pardeep S. Jhund, Kenneth Mangion, Patrick B. Mark, John J.V. McMurray, Giles Roditi, Naveed Sattar, Mark C. Petrie, Ross T. Campbell, Matthew M.Y. Lee   +11 more
wiley   +1 more source