Results 31 to 40 of about 349,810 (341)

Simultaneous submicrometric 3D imaging of the micro-vascular network and the neuronal system in a mouse spinal cord [PDF]

, 2014
Defaults in vascular (VN) and neuronal networks of spinal cord are responsible for serious neurodegenerative pathologies. Because of inadequate investigation tools, the lacking knowledge of the complete fine structure of VN and neuronal systems is a ...
Battaglia, Giuseppe, Bravin, Alberto, Brun, Francesco, Bucci, Domenico, Bukreeva, Inna, Campi, Gaetano, Cedola, Alessia, Fratini, Michela, Giove, Federico, Mastrogiacomo, Maddalena, Modregger, Peter, Requardt, Herwig, Spadon, Raffaele, Tromba, Giuliana   +13 more
core   +3 more sources

Novel Bisquaternary Oximes—Reactivation of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Paraoxon

Molecules, 2009
Four novel bisquaternary aldoxime cholinesterase reactivators differing in their chemical structure were prepared. Afterwards, their biological activity was evaluated for their ability to reactivate acetylcholinesterase (AChE; EC 3.1.1.7) and ...
Daniel Jun, Jana Zdarova Karasova, Miroslav Pohanka, Martina Hrabinova, Kamil Musilek, Martin Paar, Vladimir Cirkva, Jiri Palecek, Kamil Kuca, Lucie Musilova   +9 more
doaj   +1 more source

Characterization of the Interaction of Nerve Agent Mimics with Selected Synthetic Receptors

Organic Materials, 2022
Qualitative NMR spectroscopic and quantitative calorimetric binding studies were performed to characterize the interaction of nontoxic mimics of the V-type nerve agent VX (O-ethyl S-[2-(diisopropylamino)ethyl] methylphosphonothioate) and the Novichok ...
Carolina Braga Barbosa, Patrick Gaß, Daniel J. Hamsch, Stefan Kubik   +3 more
doaj   +1 more source

Targeted Synthesis of 1-(4-Hydroxyiminomethylpyridinium)-3-pyridiniumpropane Dibromide – A New Nerve Agent Reactivator

Molecules, 2007
Preparation of 1-(4-hydroxy-iminomethylpyridinium)-3-pyridiniumpropane dibromide is described. This compound represents a new acetylcholinesterase (AChE) reactivator, which has no substituents on the second pyridinium ring as found in other commonly used
Jan Marek, Martina Hrabinova, Petr Stodulka, Daniel Jun, Martin Paar, Kamil Musilek, Kamil Kuca   +6 more
doaj   +1 more source

Therapeutic strategy for facial paralysis based on the combined application of Si-based agent and methylcobalamin

Biochemistry and Biophysics Reports, 2022
Facial paralysis results in the decline in the generation of facial expressions and is attributed to several causes. Intractable facial paralysis has a poor prognosis, and new treatments are required.
Yoshihisa Koyama, Shotaro Harada, Takashi Sato, Yuki Kobayashi, Hiroto Yanagawa, Toru Iwahashi, Hiroyuki Tanaka, Kazuya Ohata, Takao Imai, Yumi Ohta, Takefumi Kamakura, Hikaru Kobayashi, Hidenori Inohara, Shoichi Shimada   +13 more
doaj   +1 more source

Nanoparticle drug delivery systems for inner ear therapy: An overview [PDF]

, 2017
open7noembargoed_20180701Valente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini, AlessandroValente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini,
Astolfi, Laura, Chicca, Milvia, DANTI, SERENA, Franceschini, Valeria, Martini, Alessandro, Simoni, Edi, Valente, Filippo   +6 more
core   +2 more sources

INCF Lithuanian Workshop on Neuroscience and Information Technology [PDF]

, 2012
The aim of this workshop was to give a current overview of neuroscience and informatics research in Lithuania, and to discuss the strategies for forming the Lithuanian Neuroinformatics Node and becoming a member of INCF. The workshop was organized by Dr.
Auš
core   +2 more sources

Detection of Novichok and V-Group Nerve Agents by Chemosensors Containing Nile Blue Chromophore

Chemosensors
This paper presents the results of experiments aiming for the detection and differentiation of selected nerve agents of the Novichok and V-group using simple strip detectors containing colourimetric indicator, specifically chemosensor Nile Blue A ...
Martin Urban, Tomáš Dropa, Markéta Zelenková, Michal Dymák, Vladimír Pitschmann   +4 more
doaj   +1 more source

Nerve agents in honey [PDF]

Science, 2017
Analysis of local honey samples shows global landscape contamination by ...
openaire   +2 more sources

Neurotrophic factors and corneal nerve regeneration [PDF]

, 2017
The cornea has unique features that make it a useful model for regenerative medicine studies. It is an avascular, transparent, densely innervated tissue and any pathological changes can be easily detected by slit lamp examination.
Lambiase, Alessandro, Sacchetti, Marta
core   +2 more sources