Results 41 to 50 of about 4,230,808 (299)
Characterization of the Interaction of Nerve Agent Mimics with Selected Synthetic Receptors
Organic Materials, 2022 Qualitative NMR spectroscopic and quantitative calorimetric binding studies were performed to characterize the interaction of nontoxic mimics of the V-type nerve agent VX (O-ethyl S-[2-(diisopropylamino)ethyl] methylphosphonothioate) and the Novichok ...
Carolina Braga Barbosa +3 more
doaj +1 more source
Characterizing the immune microenvironment of malignant peripheral nerve sheath tumor by PD-L1 expression and presence of CD8+ tumor infiltrating lymphocytes. [PDF]
, 2016 BackgroundMalignant peripheral nerve sheath tumor (MPNST) is an aggressive sarcoma with few treatment options. Tumor immune state has not been characterized in MPNST, and is important in determining response to immune checkpoint blockade.
Bernthal, Nicholas +11 more
core +2 more sources
Analytical Chemistry, 2019 A fluorescent chemosensor has been developed for discriminative detection of phosgene and a nerve agent mimic diethyl chlorophosphate (DCP), which was comprised of an anthracene-carboxyimide fluorophore and o-phenylenediamine (OPD) reaction site.
Lintao Zeng +5 more
semanticscholar +1 more source
Biochemistry and Biophysics Reports, 2022 Facial paralysis results in the decline in the generation of facial expressions and is attributed to several causes. Intractable facial paralysis has a poor prognosis, and new treatments are required.
Yoshihisa Koyama +13 more
doaj +1 more source
Molecules, 2009 Four novel bisquaternary aldoxime cholinesterase reactivators differing in their chemical structure were prepared. Afterwards, their biological activity was evaluated for their ability to reactivate acetylcholinesterase (AChE; EC 3.1.1.7) and ...
Daniel Jun +9 more
doaj +1 more source
Nanoparticle drug delivery systems for inner ear therapy: An overview [PDF]
, 2017 open7noembargoed_20180701Valente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini, AlessandroValente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini,
Astolfi, Laura +6 more
core +2 more sources
Detection of Novichok and V-Group Nerve Agents by Chemosensors Containing Nile Blue Chromophore
ChemosensorsThis paper presents the results of experiments aiming for the detection and differentiation of selected nerve agents of the Novichok and V-group using simple strip detectors containing colourimetric indicator, specifically chemosensor Nile Blue A ...
Martin Urban +4 more
doaj +1 more source
New strategic insights into managing fungal biofilms [PDF]
, 2015 Fungal infections have dramatically increased in the last decades in parallel with an increase of populations with impaired immunity, resulting from medical conditions such as cancer, transplantation or other chronic diseases.
Borghi, Elisa +6 more
core +11 more sources
The percutaneous absorption of soman in a damaged skin porcine model and the evaluation of WoundStat™ as a topical decontaminant [PDF]
, 2017 PURPOSE: The aim of this study was to evaluate a candidate haemostat (WoundStat™), down-selected from previous in vitro studies, for efficacy as a potential skin decontaminant against the chemical warfare agent pinacoyl methylfluorophosphonate (Soman, GD)
Chilcott, Robert P +6 more
core +2 more sources
Global Security: Health, Science and Policy, 2020 VX is a strong nerve-gas agent. In this paper, murder or injury of human made by VX is reported. First use of VX against human was made by Aum Shimrikyo in 1994 and 1995. More recently, VX was used in the assassination of Mr. Kim Jong-Nam in Kuala Lumpur,
Anthony T. Tu
doaj +1 more source