Results 51 to 60 of about 349,810 (341)

Colorimetric Detection of Warfare Gases by Polydiacetylenes Toward Equipment‐Free Detection [PDF]

, 2012
Rationally designed polydiacetylene (PDA) molecules have been developed for rapid, selective, sensitive, and convenient colorimetric detection of organophosphate (OP) nerve agents, a mass destruction weapon. Oxime (OX) functionality was incorporated into
Ahn, Bajgar, Brodeur, Cadwell, Carpick, Carpick, Chance, Dale, Dale, Harris, Joshi, Kim, Kolusheva, Lee, Lee, Lee, Lee, Lee, Leikin, Meir, Milatovic, Oh, Olmsted, Pang, Peng, Reppy, Seo, Smith, Subramaniam, Tashiro, Terrier, Yang, Yoon, Zhang   +33 more
core   +1 more source

Development of organophosphate hydrolase activity in a bacterial homolog of human cholinesterase

Frontiers in Chemistry, 2014
We applied a combination of rational design and directed evolution (DE) to Bacillus subtilis p-nitrobenzyl esterase (pNBE) with the goal of enhancing organophosphorus acid anhydride hydrolase (OPAAH) activity.
Patricia Marie Legler, Susanne eBoisvert, Jaimee R Compton, Charles B. Millard   +3 more
doaj   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Imidazole aldoximes effective in assisting butyrylcholinesterase catalysis of organophosphate detoxification. [PDF]

, 2014
Intoxication by organophosphate (OP) nerve agents and pesticides should be addressed by efficient, quickly deployable countermeasures such as antidotes reactivating acetylcholinesterase or scavenging the parent OP.
Amitai, Gabriel, Fokin, Valery V, Radić, Zoran, Sharpless, K Barry, Sit, Rakesh K, Taylor, Palmer   +5 more
core  

Comparison of Binding Affinities of Water-Soluble Calixarenes with the Organophosphorus Nerve Agent Soman (GD) and Commonly-Used Nerve Agent Simulants

Molecules, 2018
The formation of inclusion complexes of the water-soluble p-sulfonatocalix[n]arenes, where n = 4 or 6, with the Chemical Warfare Agent (CWA) GD, or Soman, and commonly used dialkyl methylphosphonate simulants has been studied by experimental solution NMR
Jayne A. Ede, Peter J. Cragg, Mark R. Sambrook   +2 more
doaj   +1 more source

The value of 3D high-resolution IR-prepared fast spoiled gradient-recalled MRI in the diagnosis of meningeal carcinomatosis involving the cranial nerves

BMC Medical Imaging, 2023
Purpose The purpose of this study was to investigate the clinical utility of three-dimension (3D) high-resolution inversion recovery (IR)-prepared fast spoiled gradient-recalled (SPGR) magnetic resonance imaging (MRI) in the diagnosis of cranial nerve ...
Lulu Xuan, Jiafu Huang, Huikang Yin, Zehua Lu, Xiaoliang Yang, Liyue Yang, Chengjun Geng   +6 more
doaj   +1 more source

Analyzing the Salisbury Incident under International Law

Public and Private International Law Bulletin, 2022
On March 04, 2018, Sergei Skripal (former Russian spy) and his daughter, Yulia Skripal, were found unconscious in Salisbury in the United Kingdom. An investigation by the authorities found that Skripal and his daughter had been exposed to Novichok nerve ...
Selman Özdan, Büşra Beydüz
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Intravenous infusion of magnesium sulfate and its effect on horses with trigeminal-mediated headshaking. [PDF]

, 2019
BackgroundTrigeminal-mediated headshaking results from low-threshold firing of the trigeminal nerve resulting in apparent facial pain. Magnesium may have neuroprotective effects on nerve firing that potentially dampen signs of neuropathic pain.
Aleman, Monica, Costa, Lais Rosa R, Howey, Quinn, Madigan, John E, Santoyo, Ana C, Sheldon, Shara A   +5 more
core   +1 more source

Exactly Restricting the Phenyl Ring Rotation in Metal‐Organic Framework for Ultra‐Sensitive and Specific Ratiometric Fluorescent Sensing of Sarin

Aggregate
To realize highly sensitive and specific sensing toward sarin, an Eu(III) based metal‐organic framework (Eu‐CTTB‐MOF), encompassing a π‐conjugated organic ligand H4CTTB (4,4′,4″,4‴‐(9H‐carbazole‐1,3,6,8‐tetrayl)tetrabenzoic acid) was explored for ...
Cong Lyu, Chuanfang Zhao, Meimei Wang, Jiawen Li, Zhenzhen Cai, Xincun Dou, Baiyi Zu   +6 more
doaj   +1 more source