Results 1 to 10 of about 175,050 (352)

Functional disability of occupational-related lumbar disc degeneration: Evaluation by magnetic resonance imaging with surgical correlation

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine, 2017
Objectives: The objectives of our work were to determine disability and study MRI findings of occupational-related lumbar disc degeneration and also to show the relationship between MRI grading of nerve root compromise with surgical grading. Participants
Alsiagy A. Salama   +5 more
doaj   +1 more source

Voluntary running delays primary degeneration in rat retinas after partial optic nerve transection

open access: yesNeural Regeneration Research, 2019
Running is believed to be beneficial for human health. Many studies have focused on the neuroprotective effects of voluntary running on animal models. There were both primary and secondary degeneration in neurodegenerative diseases, including glaucoma ...
Hong-Ying Li   +3 more
doaj   +1 more source

Neuropathophysiological potential of Guillain-Barré syndrome anti-ganglioside-complex antibodies at mouse motor nerve terminals [PDF]

open access: yes, 2011
Objectives:  Anti-ganglioside antibodies are present in approximately half of Guillain–Barré syndrome (GBS) patients. Recently, it has been shown that a considerable proportion of these patients has serum antibodies against antigenic epitopes formed by a
Susumu Kusunoki   +32 more
core   +1 more source

The concept of tissue regeneration: Epistemological and historical enquiry from early ideas on the regeneration of bone to the microscopic observations of the regeneration of peripheral nerves

open access: yesFrontiers in Cell and Developmental Biology, 2022
This paper examines the epistemological history of physiological tissue regeneration theories from Antiquity to the present time focusing on early clinical observations, microscopic investigations of the 19th C.
Jean-Gaël Barbara
doaj   +1 more source

Ingenuity pathway analysis of gene expression profiles in distal nerve stump following nerve injury: insights into Wallerian degeneration

open access: yesFrontiers in Cellular Neuroscience, 2016
Nerve injury is a common and difficult clinical problem worldwide with a high disability rate. Different from the central nervous system, the peripheral nervous system is able to regenerate after injury.
Jun Yu, Xiaosong Gu, Sheng Yi
doaj   +1 more source

ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury [PDF]

open access: yes, 2006
Neuregulin/erbB signaling is critically required for survival and proliferation of Schwann cells as well as for establishing correct myelin thickness of peripheral nerves during development.
Atanasoski, Suzana   +14 more
core   +1 more source

Dorsal Root Injury—A Model for Exploring Pathophysiology and Therapeutic Strategies in Spinal Cord Injury

open access: yesCells, 2021
Unraveling the cellular and molecular mechanisms of spinal cord injury is fundamental for our possibility to develop successful therapeutic approaches.
Håkan Aldskogius, Elena N. Kozlova
doaj   +1 more source

Critical signaling pathways during Wallerian degeneration of peripheral nerve

open access: yesNeural Regeneration Research, 2017
Wallerian degeneration is a critical biological process that occurs in distal nerve stumps after nerve injury. To systematically investigate molecular changes underlying Wallerian degeneration, we used a rat sciatic nerve transection model to examine ...
Qiong Cheng   +3 more
doaj   +1 more source

Epigenetics in glaucoma: a link between histone methylation and neurodegeneration

open access: yesThe Journal of Clinical Investigation, 2023
Normal-tension glaucoma is a form of optic nerve degeneration that is characterized by loss of retinal ganglion cells independent of eye pressure elevation. In this issue of the JCI, Pan et al.
Wendy W. Liu, Yang Sun
doaj   +1 more source

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