Results 91 to 100 of about 1,223,403 (400)

Clinical and molecular features and therapeutic perspectives of spinal muscular atrophy with respiratory distress type 1 [PDF]

open access: yes, 2015
Spinal muscular atrophy with respiratory distress (SMARD1) is an autosomal recessive neuromuscular disease caused by mutations in the IGHMBP2 gene, encoding the immunoglobulin μ-binding protein 2, leading to motor neuron degeneration.
Corti, Stefania   +4 more
core   +2 more sources

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

ATP Release through Lysosomal Exocytosis from Peripheral Nerves: The Effect of Lysosomal Exocytosis on Peripheral Nerve Degeneration and Regeneration after Nerve Injury

open access: yesBioMed Research International, 2014
Studies have shown that lysosomal activation increases in Schwann cells after nerve injury. Lysosomal activation is thought to promote the engulfment of myelin debris or fragments of injured axons in Schwann cells during Wallerian degeneration.
Junyang Jung   +3 more
semanticscholar   +1 more source

Müller glia activation in response to inherited retinal degeneration is highly varied and disease-specific [PDF]

open access: yes, 2015
Despite different aetiologies, most inherited retinal disorders culminate in photoreceptor loss, which induces concomitant changes in the neural retina, one of the most striking being reactive gliosis by Müller cells.
Ali, RR   +6 more
core   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

open access: yesAdvanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana   +2 more
wiley   +1 more source

Generalized nerves of monads [PDF]

open access: yesarXiv, 2022
One interpretation of the Kleisli construction (given by Miranda and related to work of Par\'e) is as a nerve sending a monad $P$ to the Kleisli double category of $P$. In this paper we find more general nerve constructions on the 2-categories of monads, which also give fully faithful nerve 2-functors $\mathbf{Mnd}\left(\mathcal{K}\right)\to\mathbf{Dbl}
arxiv  

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

open access: yesAdvanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao   +5 more
wiley   +1 more source

Diffusion weighted MRI and tractography for evaluating peripheral nerve degeneration and regeneration

open access: yesNeural Regeneration Research, 2014
Accurately documenting and quantifying peripheral nerve axonal degeneration and regeneration is critically important for clinical research in peripheral nerve disorders such as nerve trauma, peripheral neuropathy and amyotrophic lateral sclerosis (ALS ...
N. Simon, M. Kliot
semanticscholar   +1 more source

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