Results 141 to 150 of about 175,050 (352)

Quantitative evaluation of rat sciatic nerve degeneration using high-frequency ultrasound. [PDF]

Sci Rep, 2023
Wu Y, Barrere V, Han A, Andre MP, Orozco E, Cheng X, Chang EY, Shah SB.   +7 more
europepmc   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Statistical modelling of neuron degeneration [PDF]

, 2013
SUMMARY: Parkinson’s disease, Huntington’s disease, Amyotrophic lateral sclerosis (ALS) and Alzheimer’s disease are all examples of neurodegenerative disorders that result from the premature death of nerve cells or neurons.
Henderson, Robert, Pettitt, Tony, McCombe, Pam, Ridall, Gareth   +3 more
core  

Axonal protection by Nmnat3 overexpression with involvement of autophagy in optic nerve degeneration [PDF]

, 2013
Yasushi Kitaoka, Yasunari Munemasa, Kaori Kojima, Ayano Hirano, Satoki Ueno, Hitoshi Takagi   +5 more
openalex   +1 more source

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

Axonal  -synuclein aggregates herald centripetal degeneration of cardiac sympathetic nerve in Parkinson's disease [PDF]

, 2007
Satoshi Orimo, Toshiki Uchihara, Ayako Nakamura, Fumiaki Mori, A. Kakita, Koichi Wakabayashi, Hitoshi Takahashi   +6 more
openalex   +1 more source

Exercício físico de baixa intensidade na terapêutica da dor neuropática e regeneração nervosa periférica: efeitos neurobiológicos e estudo dos mecanismos de ação [PDF]

, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2015.A dor neuropática que surge em decorrência da lesão de nervos espinais é caracterizada por uma ...
Bobinski, Franciane
core  

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

Novel neuron-Schwann cell co-culture models to study peripheral nerve degeneration and regeneration. [PDF]

Neural Regen Res, 2023
Sango K.
europepmc   +1 more source

Nerve Degeneration:

, 1879
n ...
openaire   +1 more source