Results 21 to 30 of about 656,858 (381)
Neural Regeneration Research, 2015 OBJECTIVE: China is the only country where nerve growth factor is approved for large-scale use as a clinical medicine. More than 10 years ago, in 2003, nerve growth factor injection was listed as a national drug.
Meng Zhao +3 more
doaj +1 more source
Exogenous nerve growth factor protects the hypoglossal nerve against crush injury
Neural Regeneration Research, 2015 Studies have shown that sensory nerve damage can activate the p38 mitogen-activated protein kinase (MAPK) pathway, but whether the same type of nerve injury after exercise activates the p38MAPK pathway remains unclear.
Li-yuan Fan +4 more
doaj +1 more source
Scattered Light Imaging: Resolving the substructure of nerve fiber crossings in whole brain sections with micrometer resolution [PDF]
NeuroImage 233, 117952 (2021), 2020 For developing a detailed network model of the brain based on image reconstructions, it is necessary to spatially resolve crossing nerve fibers. The accuracy hereby depends on many factors, including the spatial resolution of the imaging technique. 3D Polarized Light Imaging (3D-PLI) allows the three-dimensional reconstruction of nerve fiber tracts in ...
arxiv +1 more source
Effects of a synthetic bioactive peptide on neurite growth and nerve growth factor release in chondroitin sulfate hydrogels. [PDF]
, 2011 Previous work has revealed robust dorsal root ganglia neurite growth in hydrogels of chondroitin sulfate. In the current work, it was determined whether addition of a synthetic bioactive peptide could augment neurite growth in these matrices via enhanced
Beier, Brooke L +3 more
core +1 more source
ProNGF-p75NTR axis plays a proinflammatory role in inflamed joints. A novel pathogenic mechanism in chronic arthritis [PDF]
, 2017 To identify the role of mature nerve growth factor (mNGF), its immature form proNGF and their receptors in arthritis ...
Benedetti, Fabrizio De +9 more
core +1 more source
Nerve growth factor, mast cells and arthritis [PDF]
, 1995 Nerve growth factor is a well-characterized neurotrophic protein required for the survival and differentiation of a variety of neuronal cell types both in the peripheral and central nervous systems.
Aloe, Luigi +2 more
core +2 more sources
Nihon Naika Gakkai Zasshi, 1992 神経成長因子(nerve growth factor; NGF)は,知覚神経二ューロン,交感神経ニューロン,中枢の一部のコリン系ニューロンの分化・成熟を促し,生存・機能を維持し,突起伸展を引き起こす,分子量約26000の蛋白質である. NGFは,神経科学,発生学の分野において最も古くから実体の明らかにされていた分子のひとつで, NGFの研究で得られた膨大な知見から神経回路の形成過程や調節機構の概要が窺い知ることができるようになった.最近では, NGFを投与すると,末梢神経の軸索再生が促進されること,遅発性ニューロン死が抑制されること,老化による学習記憶能力低下が抑制されること,などが報告され,臨床応用への期待も高まってきている.
Furukawa S, Furukawa Y
openaire +4 more sources
Expression and Function of Neurotrophins and Their Receptors in Cultured Human Keratinocytes [PDF]
, 2003 Whereas nerve growth factor has been extensively studied in human keratinocytes, little is known on the role of other members of the neurotrophin family.
Bonté, F. +9 more
core +1 more source
Transforming growth factor-β stimulates nerve growth factor production in osteoarthritic synovium
BMC Musculoskeletal Disorders, 2019 Background Nerve growth factor (NGF) contributes to pain in knee osteoarthritis (KOA) patients. Transforming growth factor-beta (TGF-β) stimulates NGF expression in chondrocytes from KOA patients.
Shotaro Takano +10 more
doaj +1 more source
Neural Regeneration Research, 2020 The regenerative capacity of peripheral nerves is limited after nerve injury. A number of growth factors modulate many cellular behaviors, such as proliferation and migration, and may contribute to nerve repair and regeneration.
Yin-Ying Shen +5 more
doaj +1 more source