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Inhibition of .beta. nerve growth factor binding to PC12 cells by .alpha. nerve growth factor and .gamma. nerve growth factor

Biochemistry, 1986
Pheochromocytoma (PC12) cells have been found to differ from dorsal root ganglionic cells with respect to the modulation of the beta nerve growth factor (beta NGF) binding properties elicited by alpha NGF and gamma NGF. In contrast to our previous results with intact dorsal root ganglionic cells in which only high-affinity binding was blocked, alpha ...
N R, Woodruff, K E, Neet
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Nerve Growth Factor: Neurotrophin or Cytokine?

International Archives of Allergy and Immunology, 2003
Nerve growth factor (NGF) is a neutrophin exerting an important role in the development and functions of the central and peripheral nervous system. However, it has recently been documented that several immune cells – such as mast cells, lymphocytes and eosinophils – produce, store and release NGF.
BONINI, Sergio   +4 more
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Tissue Localization of Nerve Growth Factor and Nerve Growth Factor Receptors

1991
The pioneering investigations of Levi-Montalcini and coworkers established that nerve growth factor (NGF) is an important physiological regulator of neurons of the peripheral nervous system. No doubt in part because of the dramatic and specific effects on the sympathetic and sensory nervous system resulting from immunochemically depriving rodents of ...
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The nerve growth factor family

Progress in Growth Factor Research, 1990
Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) are small, basic, secretory proteins that allow the survival of specific neuronal populations. In their biologically active form, after cleavage from their biosynthetic precursors, these three neurotrophic proteins, or neurotrophins, show about 50% amino acid ...
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Nerve growth factor and the neostriatum

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 1991
1. The present review summarizes evidence describing the expression, immunoreactivity, binding, transport, development, aging, and functions of NGF in the mammalian neostriatum. 2. Neostriatal NGF binding sites and intrinsic cholinergic neurons are co-localized, increase at a similar rate during ontogeny, and are lost to an equal extent following age ...
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Regulation of the Synthesis of Nerve Growth Factor and Nerve Growth Factor Receptor

1988
The importance of Nerve Growth Factor (NGF) for the development and the maintenance of differentiated properties of peripheral sympathetic and neural crest- derived sensory neurons as well as for basal forebrain cholinergic neurons is well established (cf Levi-Montalcini & Angeletti, 1968; Greene & Shooter, 1980; Thoenen & Barde, 1980; Thoenen et al ...
R. Heumann   +7 more
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The Nerve-Growth Factor

Scientific American, 1979
R, Levi-Montalcini, P, Calissano
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NERVE GROWTH FACTOR

Developmental Medicine & Child Neurology, 1976
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Nerve growth factor.

Ciba Foundation symposium, 1986
In contrast to all other molecules which are labelled 'growth factor', NGF is not a mitogen. It is a neurotrophic molecule essential for the development and maintenance of function of specific populations of peripheral and possibly also central neurons. The availability of NGF in large quantities from exocrine glands (e.g.
H, Thoenen   +3 more
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