Results 251 to 260 of about 480,406 (311)
Some of the next articles are maybe not open access.
1977
Publisher Summary Nerve growth factor (NGF) is one of an increasing number of growth factors that has been recognized as being essential for the survival and maintenance of specific types of cells. This chapter discusses the nerve growth factor from mouse submaxillary gland, the high molecular weight form of NGF (7 S NGF), the biosynthesis of NGF ...
A C, Server, E M, Shooter
openaire +2 more sources
Publisher Summary Nerve growth factor (NGF) is one of an increasing number of growth factors that has been recognized as being essential for the survival and maintenance of specific types of cells. This chapter discusses the nerve growth factor from mouse submaxillary gland, the high molecular weight form of NGF (7 S NGF), the biosynthesis of NGF ...
A C, Server, E M, Shooter
openaire +2 more sources
International Journal of Neuroscience, 1985
Nerve growth factor is a polypeptide hormone that is required for the normal growth and development of the embryonic sensory and sympathetic nervous systems. On these cells, there are two different receptors for the nerve growth factor. Recently, these receptors have been isolated from three cell types and shown to have essentially the same binding ...
R W, Stach +3 more
openaire +2 more sources
Nerve growth factor is a polypeptide hormone that is required for the normal growth and development of the embryonic sensory and sympathetic nervous systems. On these cells, there are two different receptors for the nerve growth factor. Recently, these receptors have been isolated from three cell types and shown to have essentially the same binding ...
R W, Stach +3 more
openaire +2 more sources
Growth regulation by nerve growth factor
Molecular and Cellular Biochemistry, 1979Although a great deal of descriptive information has been obtained about the actions of nerve growth factor on its target tissues, its structure, its receptors, and even its biosynthesis, there is no clear understanding, as yet, of the intracellular events mediating its transcriptional involvements.
T, Ikeno, G, Guroff
openaire +2 more sources
Nerve growth factor as an angiogenic factor
Microvascular Research, 2008Nerve growth factor (NGF), a neurotrophin that plays a crucial role in promoting neurotrophic and neurotropic effects in sympathetic neurons, has recently been identified as a novel angiogenic molecule, which exerts a variety of effects in the cardiovascular system and on endothelial cells.
BENAGIANO V +4 more
openaire +4 more sources
On the immunology of nerve growth factor
Neuroscience Letters, 1985We report some experiments on the immunological properties of nerve growth factor from the venom of Heloderma horridum and from bull seminal vesicles. On the basis of these results, taken together with results already in the literature, we propose an operational definition of the term nerve growth factor.
B E, Banks +3 more
openaire +2 more sources
Nerve growth factor and nociception
Trends in Neurosciences, 1993Nerve growth factor (NGF) is thought of as a target-derived factor responsible for the survival and maintaining the phenotype of specific sets of peripheral and central neurons during development and maturation. Recently, using physiological techniques, we have shown that specific functional types of nociceptive sensory neurons require NGF, first for ...
G R, Lewin, L M, Mendell
openaire +2 more sources
Trends in Biochemical Sciences, 1993
Recent studies on nerve growth factor have revealed important new insights into the structure, function and evolution of this prototypical neurotrophic factor. Some of its features are (1) it has a unique three-dimensional fold that has since been found in two other growth factors, (2) it uses the trk proto-oncogene product, which has a tyrosine kinase,
R A, Bradshaw +4 more
openaire +2 more sources
Recent studies on nerve growth factor have revealed important new insights into the structure, function and evolution of this prototypical neurotrophic factor. Some of its features are (1) it has a unique three-dimensional fold that has since been found in two other growth factors, (2) it uses the trk proto-oncogene product, which has a tyrosine kinase,
R A, Bradshaw +4 more
openaire +2 more sources
Receptors for Nerve Growth Factor
1993Publisher Summary This chapter discusses the two receptors for nerve growth factor (NGF)—namely, (1) the low-affinity NGF receptor and (2) the product of the proto-oncogene trk . It also reviews the way they were originally identified and the structural and functional features of the two receptors.
M V, Chao, D S, Battleman, M, Benedetti
openaire +2 more sources
Human nerve growth factor: Lack of immunocrossreactivity with mouse nerve growth factor
Life Sciences, 1980Abstract Human β-nerve growth factor (hNGF) was purified from term human placenta. The biological potency of hNGF in the chick dorsal root ganglion assay did not differ significantly from that of mouse NGF (mNGF). Molecular weight determinations of mNGF and hMGF were also similar.
P, Walker, M E, Weichsel, D A, Fisher
openaire +2 more sources
Biochemistry, 1986
Pheochromocytoma (PC12) cells have been found to differ from dorsal root ganglionic cells with respect to the modulation of the beta nerve growth factor (beta NGF) binding properties elicited by alpha NGF and gamma NGF. In contrast to our previous results with intact dorsal root ganglionic cells in which only high-affinity binding was blocked, alpha ...
N R, Woodruff, K E, Neet
openaire +2 more sources
Pheochromocytoma (PC12) cells have been found to differ from dorsal root ganglionic cells with respect to the modulation of the beta nerve growth factor (beta NGF) binding properties elicited by alpha NGF and gamma NGF. In contrast to our previous results with intact dorsal root ganglionic cells in which only high-affinity binding was blocked, alpha ...
N R, Woodruff, K E, Neet
openaire +2 more sources