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Wound repair is a key step in the treatment of skin injury caused by burn, surgery, and trauma. Various stem cells have been proven to promote wound healing and skin regeneration as candidate seed cells.
Ziying Zhu+8 more
doaj +1 more source
KLF9 and JNK3 Interact to Suppress Axon Regeneration in the Adult CNS [PDF]
Neurons in the adult mammalian CNS decrease in intrinsic axon growth capacity during development in concert with changes in Krüppel-like transcription factors (KLFs). KLFs regulate axon growth in CNS neurons including retinal ganglion cells (RGCs). Here,
Apara, Akintomide+16 more
core +2 more sources
The role of growth factors in nerve regeneration.
Nerve injuries result in functional loss in the innervated organ or body parts, and recovery is difficult unless surgical treatment has been done. Different surgical treatments have been suggested for nerve repair.
M. Önger+5 more
semanticscholar +1 more source
Trophic and neurotrophic factors in human pituitary adenomas (Review) [PDF]
The pituitary gland is an organ that functionally connects the hypothalamus with the peripheral organs. The pituitary gland is an important regulator of body homeostasis during development, stress, and other processes.
Agostinelli, Enzo+11 more
core +1 more source
Wangseok Do,1 Jiseok Baik,1,2 Soeun Jeon,1 Chang-Min You,1 Dahyun Kang,1 Young-Hoon Jung,1 Jiyoon Lee,3 Hae-Kyu Kim1,2 1Department of Anesthesia and Pain Medicine and Biomedical Research Institute Pusan National University Hospital, Busan, Republic of ...
Do W+7 more
doaj
Largely on the basis of studies with nerve growth factor (NGF), it is now widely accepted that development of the peripheral nervous system of vertebrates is dependent in part on the interaction of immature sensory and autonomic neurons with specific ...
R. Lindsay
semanticscholar +1 more source
神経成長因子(nerve growth factor; NGF)は,知覚神経二ューロン,交感神経ニューロン,中枢の一部のコリン系ニューロンの分化・成熟を促し,生存・機能を維持し,突起伸展を引き起こす,分子量約26000の蛋白質である. NGFは,神経科学,発生学の分野において最も古くから実体の明らかにされていた分子のひとつで, NGFの研究で得られた膨大な知見から神経回路の形成過程や調節機構の概要が窺い知ることができるようになった.最近では, NGFを投与すると,末梢神経の軸索再生が促進されること,遅発性ニューロン死が抑制されること,老化による学習記憶能力低下が抑制されること,などが報告され,臨床応用への期待も高まってきている.
Furukawa S, Furukawa Y
openaire +4 more sources
Background: Late Onset Bipolar Disorder (LOBD) is the development of Bipolar Disorder (BD) at an age above 50 years old. It is often difficult to differentiate from other aging dementias, such as Alzheimer's Disease (AD), because they share cognitive and
Ariadna Besga+12 more
doaj +1 more source
Clues from Crouzon: Insights into the potential role of growth factors in the pathogenesis of myelinated retinal nerve fibers. [PDF]
PurposeWe present a case of bilateral extensive peripapillary myelinated retinal nerve fibers (MRNF) in an individual with Crouzon syndrome, an inherited form of craniosynostosis caused by overactivation of fibroblast growth factor receptor 2.
Akil, Handan+5 more
core +3 more sources
Polymer- and Hybrid-Based Biomaterials for Interstitial, Connective, Vascular, Nerve, Visceral and Musculoskeletal Tissue Engineering [PDF]
In this review, materials based on polymers and hybrids possessing both organic and inorganic contents for repairing or facilitating cell growth in tissue engineering are discussed.
Abalymov, Anatolii+2 more
core +1 more source