Results 21 to 30 of about 223,909 (214)

Application of neurotrophic and proangiogenic factors as therapy after peripheral nervous system injury

Neural Regeneration Research, 2022
The intrinsic ability of peripheral nerves to regenerate after injury is extremely limited, especially in case of severe injury. This often leads to poor motor function and permanent disability.
Kamilla Faritovna Idrisova, Alina Kazymovna Zeinalova, Galina Andreevna Masgutova, Alexey Andreevich Bogov, Cinzia Allegrucci, Valeriia Yurievna Syromiatnikova, Ilnur Ildusovich Salafutdinov, Ekaterna Evgenievna Garanina, Dina Ivanovna Andreeva, Adilet Abdullaatovich Kadyrov, Albert Anatolevich Rizvanov, Ruslan Faridovich Masgutov   +11 more
doaj   +1 more source

Neuropeptídeos na pele Neuropeptides in the skin

Anais Brasileiros de Dermatologia, 2003
Há evidências crescentes de que a inervação cutânea é capaz de modular uma variedade de fenômenos cutâneos agudos e crônicos, interagindo com as células da pele e seus componentes imunes.
Pedro Kalil-Gaspar
doaj   +1 more source

Morphofunctional regeneration by mesenchymal stem cell and IGF-1 inoculation in a model of facial nerve crush injury in rats

Brazilian Journal of Otorhinolaryngology, 2023
Objective: To analyze the morphofunctional regeneration process of facial nerve injury in the presence of insulin-like growth factor-1 and mesenchymal stem cells.
Aracele Gonçalves Vieira, Fausto Pierdona Guzen, José Rodolfo Lopes de Paiva, Lucídio Clebeson de Oliveira, Maria Clara de Araújo Jales, Eudes Euler de Souza Lucena, Virgínia Raquel dos Santos Lucena, Hécio Henrique Araújo de Morais   +7 more
doaj   +1 more source

Nerve growth factor binding domain of the nerve growth factor receptor. [PDF]

Proceedings of the National Academy of Sciences, 1991
A structural analysis of the rat low-affinity nerve growth factor (NGF) receptor was undertaken to define the NGF binding domain. Mutant NGF receptor DNA constructs were expressed in mouse fibroblasts or COS cells, and the ability of the mutant receptor to bind NGF was assayed.
Catherine M. Bitler, Eric M. Shooter, Monte J. Radeke, Andrew A. Welcher   +3 more
openaire   +3 more sources

A ‘Relay’-Type Drug-Eluting Nerve Guide Conduit: Computational Fluid Dynamics Modeling of the Drug Eluting Efficiency of Various Drug Release Systems

Pharmaceutics, 2022
Nerve guidance conduits (NGCs) are tubular scaffolds that act as a bridge between the proximal and distal ends of the native nerve to facilitate the nerve regeneration.
Jiarui Zhou, Sanjairaj Vijayavenkataraman   +1 more
doaj   +1 more source

Peripheral nerve injury recovery enhanced by ceftriaxone: a preclinical investigation [PDF]

Acta Cirúrgica Brasileira
Purpose: To evaluate ceftriaxone’s potential in enhancing peripheral nerve injuries (PNIs) recovery. Methods: Thirty male Wistar rats were divided into control (no surgery), vehicle (sciatic nerve injury + 0.9% NaCl), and ceftriaxone (sciatic nerve ...
Berkin Gunar, Ejder Saylav Bora, Osman Mert Topkar, Özgür Baysal, Ziya Shammadli, Oytun Erbas   +5 more
doaj   +1 more source

Can ReGeneraTing Agents Improve Functional Recovery of Transected Peripheral Nerve through a Nerve Gap Bridged with an Artery Graft?

Journal of Reconstructive Microsurgery Open, 2019
Background The purpose of this study was to use artery grafts filled with CACIPLIQ20 and see if they promote nerve regeneration. Methods Sixty male Wistar rats were used. The rats were randomly divided into four experimental groups (n = 15):
George Alexopoulos, Leonidas Pavlidis, Myron Tsagarakis, Alexandros Delimpaltas, Antonios Tsimponis, Apostolos Papalois, Anna Batistatou, Alexandra Papoudou-Bai, Denis Barritault, Efterpi Demiri, Georgia Alexandra Spyropoulou   +10 more
doaj   +1 more source

Nerve Growth Factor and Autoimmune Diseases

Current Issues in Molecular Biology, 2023
NGF plays a crucial immunomodulatory role and increased levels are found in numerous tissues during autoimmune states. NGF directly modulates innate and adaptive immune responses of B and T cells and causes the release of neuropeptides and neurotransmitters controlling the immune system activation in inflamed tissues.
Sergio Terracina, Giampiero Ferraguti, Luigi Tarani, Francesca Fanfarillo, Paola Tirassa, Massimo Ralli, Giannicola Iannella, Antonella Polimeni, Marco Lucarelli, Antonio Greco, Marco Fiore   +10 more
openaire   +5 more sources

Analysis of post-traumatic growth status and its influencing factors in patients with facial palsy

Chinese Neurosurgical Journal, 2018
Background Facial nerve paralysis in patients occurs in varying degrees of self-image disorders, both physically and mentally, resulting in low self-esteem, anxiety, depression, and even suicide; however, there were few researches on psychological ...
Qian Li, Pengwei Lu, Yanzhu Fan, Lei Wang, Fei Yao, Diya Su   +5 more
doaj   +1 more source

The use of rh-NGF in the management of neurotrophic keratopathy

Frontiers in Ophthalmology
Neurotrophic keratitis or keratopathy (NK) is a degenerative corneal disease induced by impairment of the trigeminal nerve function. This condition may lead to persistent epithelial defects, corneal ulceration, and perforation.
Anna M. Roszkowska, Anna M. Roszkowska, Rosaria Spinella, Alessandro Calderone, Marianna Sindoni, Bogumił H. Wowra, Maciej Kozak, Katarzyna Sajak-Hydzik, Jorge Aliò   +8 more
doaj   +1 more source