Results 1 to 10 of about 1,563,345 (405)
The gut metabolite indole-3 propionate promotes nerve regeneration and repair
The regenerative potential of mammalian peripheral nervous system neurons after injury is critically limited by their slow axonal regenerative rate1. Regenerative ability is influenced by both injury-dependent and injury-independent mechanisms2.
, Guiping Kong, Luming Zhou
exaly +2 more sources
A small molecule screen identifies in vivo modulators of peripheral nerve regeneration in zebrafish. [PDF]
Adult vertebrates have retained the ability to regenerate peripheral nerves after injury, although regeneration is frequently incomplete, often leading to functional impairments.
Juliane Bremer +2 more
doaj +9 more sources
Magnesium Promotes the Regeneration of the Peripheral Nerve
Peripheral nerve injury is a common complication in trauma, and regeneration and function recovery are clinical challenges. It is indispensable to find a suitable material to promote peripheral nerve regeneration due to the limited capacity of peripheral
Jingxin Zhang +5 more
doaj +2 more sources
Nerve guidance conduits (NGCs) have become a promising alternative for peripheral nerve regeneration; however, the outcome of nerve regeneration and functional recovery is greatly affected by the physical, chemical, and electrical properties of NGCs.
Yongcong Fang +8 more
semanticscholar +1 more source
Self-renewing macrophages in dorsal root ganglia contribute to promote nerve regeneration
Significance Peripheral sensory neurons situated in dorsal root ganglia (DRG) switch to a regenerative state after nerve injury to enable nerve repair. Axon regeneration is not cell autonomous and is highly influenced by nonneuronal cells.
Rui Feng +3 more
semanticscholar +1 more source
A Bioinspired Self‐Healing Conductive Hydrogel Promoting Peripheral Nerve Regeneration
The development of self‐healing conductive hydrogels is critical in electroactive nerve tissue engineering. Typical conductive materials such as polypyrrole (PPy) are commonly used to fabricate artificial nerve conduits.
Hongyun Xuan +8 more
semanticscholar +1 more source
The pleiotropic role of the major histocompatibility complex class I (MHC-I) reflects the close association between the nervous and immune systems. In turn, MHC-I upregulation postinjury is associated with a better regenerative outcome in isogenic mice ...
Bruno Henrique de Melo Lima +3 more
doaj +1 more source
Enhanced peripheral nerve regeneration by mechano-electrical stimulation
To address limitations in current approaches for treating large peripheral nerve defects, the presented study evaluated the feasibility of functional material-mediated physical stimuli on peripheral nerve regeneration.
Youyi Tai +5 more
semanticscholar +1 more source
Peripheral nerve injury is a challenging orthopedic condition that can be treated by autograft transplantation, a gold standard treatment in the current clinical setting.
Zhi Yao +14 more
semanticscholar +1 more source
HDAC-6 inhibition ameliorates the early neuropathology in a mouse model of Krabbe disease
IntroductionIn Krabbe disease (KD), mutations in β-galactosylceramidase (GALC), a lysosomal enzyme responsible for the catabolism of galactolipids, leads to the accumulation of its substrates galactocerebroside and psychosine.
Sandra O. Braz +8 more
doaj +1 more source

