Results 121 to 130 of about 1,438,567 (364)

A repeated strike loading organ culture model for studying compression-associated chronic disc degeneration

open access: yesBiomolecules & Biomedicine
Mechanical stress has been viewed as one of the key risk factors in accelerating the intervertebral disc degeneration process. The goal of the present study was to employ a repeated strike loading bovine caudal disc system to elucidate the ...
Baoliang Li   +10 more
doaj   +1 more source

Peripheral nerve injury induced changes in the spinal cord and strategies to counteract/enhance the changes to promote nerve regeneration

open access: yesNeural Regeneration Research, 2019
Peripheral nerve injury leads to morphological, molecular and gene expression changes in the spinal cord and dorsal root ganglia, some of which have positive impact on the survival of neurons and nerve regeneration, while the effect of others is the ...
Yan Liu, Huan Wang
semanticscholar   +1 more source

Buckling‐Resistant and Trace‐Stacked (BRATS) Design Enables Aid‐Free Implantation of Flexible Multielectrode Array with Minimized Inflammatory Tissue Response

open access: yesAdvanced Functional Materials, EarlyView.
Buckling‐resistant and trace‐stacked (BRATS) intracortical microelectrode arrays (MEAs) eliminate the need for insertion aid and complex surgical setup, resulting in minimal inflammatory tissue response, compared to conventional flexible MEAs inserted with aid. Trace stacking effectively doubled the channel count without increasing the MEA shank width,
May Yoon Pwint, Delin Shi, X. Tracy Cui
wiley   +1 more source

Biomimetic Photocurable Three-Dimensional Printed Nerve Guidance Channels with Aligned Cryomatrix Lumen for Peripheral Nerve Regeneration.

open access: yesACS Applied Materials and Interfaces, 2018
Repair and regeneration of critically injured peripheral nerves is one of the most challenging reconstructive surgeries. Currently available and FDA approved nerve guidance channels (NGCs) are suitable for small gap injuries, and their biological ...
Anamika Singh   +8 more
semanticscholar   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz   +3 more
wiley   +1 more source

Design of AgNPs loaded γ-PGA chitosan conduits with superior antibacterial activity and nerve repair properties

open access: yesFrontiers in Bioengineering and Biotechnology
To address the challenge of infections during peripheral nerve defect repair, this study introduces a γ-polyglutamic acid (γ-PGA) polymers designed to encapsulate silver nanoparticles (AgNPs).
Yang Qu   +28 more
doaj   +1 more source

Dual‐Phased Molybdenum Carbides Confined in MOF‐Derived Carbon Nanoframes Enhance Capacitive Desalination

open access: yesAdvanced Functional Materials, EarlyView.
Dual‐phase MoC/Mo2C/CoNC nanoframes are synthesized via a MOF‐on‐MOF strategy, demonstrating a large salt adsorption capacity, a low energy consumption, and an excellent cycling stability. In situ/ex situ characterizations and DFT calculations reveal that the MoC/Mo2C dual phase transition facilitates Na+ adsorption/desorption, while interface‐induced ...
Feifei Pang   +8 more
wiley   +1 more source

The effects of mechanical stimulation on the morphology and function of spinal ligament cells

open access: yesBMC Musculoskeletal Disorders
Background It has been shown that mechanical signaling in the cellular microenvironment is crucial for control at the cellular and tissue levels, affecting human growth and the prevalence of disease.
Tao Tang   +5 more
doaj   +1 more source

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