Results 21 to 30 of about 1,499,008 (358)

Biomimetic nerve guidance conduit containing engineered exosomes of adipose-derived stem cells promotes peripheral nerve regeneration

Stem cell research & therapeutics, 2021
Background Efficient and stable delivery of neurotrophic factors (NTFs) is crucial to provide suitable microenvironment for peripheral nerve regeneration.
Zheng Yang, Yang Yang, Yichi Xu, Weiqian Jiang, Yan Shao, Jiahua Xing, Youbai Chen, Yan Han   +7 more
semanticscholar   +1 more source

Pure-silk fibroin hydrogel with stable aligned micropattern toward peripheral nerve regeneration

Nanotechnology Reviews, 2021
Successful repair of long-distance peripheral nerve injuries remains a challenge in the clinic. Rapid axon growth is a key to accelerate nerve regeneration.
Gu Xinyi, Chen Xiaoli, Tang Xiaoxuan, Zhou Zhihao, Huang Tingting, Yang Yumin, Ling Jue   +6 more
doaj   +1 more source

Mesenchymal Stem Cell Treatment Perspectives in Peripheral Nerve Regeneration: Systematic Review

International Journal of Molecular Sciences, 2021
Traumatic peripheral nerve lesions affect hundreds of thousands of patients every year; their consequences are life-altering and often devastating and cause alterations in movement and sensitivity.
Andrea Lavorato, Stefania Raimondo, M. Boido, L. Muratori, Giorgia Durante, F. Cofano, F. Vincitorio, S. Petrone, P. Titolo, F. Tartara, A. Vercelli, D. Garbossa   +11 more
semanticscholar   +1 more source

Tissue Engineering Strategies for Peripheral Nerve Regeneration

Frontiers in Neurology, 2021
A peripheral nerve injury (PNI) has severe and profound effects on the life of a patient. The therapeutic approach remains one of the most challenging clinical problems.
Yin Li, Zhenjiang Ma, Ya Ren, Dezhi Lu, Tao Li, Wentao Li, Jinwu Wang, Hui Ma, Jie Zhao   +8 more
semanticscholar   +1 more source

Nerve Guidance Conduits with Hierarchical Anisotropic Architecture for Peripheral Nerve Regeneration

Advanced Healthcare Materials, 2021
Nerve guidance conduits with multifunctional features could offer microenvironments for improved nerve regeneration and functional recovery. However, the challenge remains to optimize multiple cues in nerve conduit systems due to the interplay of these ...
Q. Lu, Feng Zhang, Weinan Cheng, Xiang Gao, Z. Ding, Xiaoyi Zhang, Q. Lu, D. Kaplan   +7 more
semanticscholar   +1 more source

Cortical plasticity and nerve regeneration after peripheral nerve injury

Neural Regeneration Research, 2021
With the development of neuroscience, substantial advances have been achieved in peripheral nerve regeneration over the past decades. However, peripheral nerve injury remains a critical public health problem because of the subsequent impairment or ...
Ci Li, Song-yang Liu, W. Pi, Pei-Xun Zhang   +3 more
semanticscholar   +1 more source

Biomechanical Properties of Bionic Collum Femoris Preserving Hip Prosthesis: A Finite Element Analysis

Orthopaedic Surgery, 2023
Objective Compared with total hip replacement, conventional collum femoris preserving prosthesis has a better bone retention effect. However, damage to the trabecular bone of the proximal femur leads to inevitable abnormal stress distribution, which ...
Xiaomeng Zhang, Yanhua Wang, Lijia Zhang, Kai Yu, Zhentao Ding, Yichong Zhang, Xiaofeng Chen, Chen Xiong, Yun Ji, Dianying Zhang, Xinlong Ma   +10 more
doaj   +1 more source

Nerve growth factor activates autophagy in Schwann cells to enhance myelin debris clearance and to expedite nerve regeneration

Theranostics, 2020
Rationale: Autophagy in Schwann cells (SCs) is crucial for myelin debris degradation and clearance following peripheral nerve injury (PNI). Nerve growth factor (NGF) plays an important role in reconstructing peripheral nerve fibers and promoting axonal ...
Rui Li, Duo-hui Li, Chengbiao Wu, Li-bing Ye, Yanqing Wu, Yuan Yuan, Shengnan Yang, Ling Xie, Yuqin Mao, Ting Jiang, Yiyang Li, Jian Wang, Hongyu Zhang, Xiaokun Li, Jian Xiao   +14 more
semanticscholar   +1 more source

The interaction of stem cells and vascularity in peripheral nerve regeneration

Neural Regeneration Research, 2021
The degree of nerve regeneration after peripheral nerve injury can be altered by the microenvironment at the site of injury. Stem cells and vascularity are postulated to be a part of a complex pathway that enhances peripheral nerve regeneration; however,
S. Saffari, T. Saffari, D. Ulrich, S. Hovius, A. Shin   +4 more
semanticscholar   +1 more source

Comparative intra- and inter-observer reliability of two methods for evaluating intraoperative ultrasonography-based spinal cord hyperechogenicity intensity in degenerative cervical myelopathy

BMC Musculoskeletal Disorders, 2022
Objectives During French-door laminoplasty, a linear array transducer of IOUS was used to observe and record the spinal cord decompression. To acquire a higher-reliability method, and compare the in-observer and inter-observer reliability of two methods ...
Huachuan Wu, Guoliang Chen, Xianlong Li, Zhengya Zhu, Zuofeng Xu, Xizhe Liu, Shaoyu Liu   +6 more
doaj   +1 more source