Results 21 to 30 of about 17,599 (272)
Advances and Pitfalls of Cell Therapy in Metabolic Leukodystrophies
Cell Transplantation, 2013 Leukodystrophies are a group of disorders characterized by myelin dysfunction, either at the level of myelin formation or maintenance, that affect the central nervous system (CNS) and also in some cases, to a lesser extent, the peripheral nervous system (
Catarina Oliveira Miranda +3 more
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Non-Muscle Myosin II in Axonal Cell Biology: From the Growth Cone to the Axon Initial Segment
Cells, 2020 By binding to actin filaments, non-muscle myosin II (NMII) generates actomyosin networks that hold unique contractile properties. Their dynamic nature is essential for neuronal biology including the establishment of polarity, growth cone formation and ...
Ana Rita Costa, Monica M. Sousa
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The Role of Spastin in Axon Biology
Frontiers in Cell and Developmental Biology, 2022 Neurons are highly polarized cells with elaborate shapes that allow them to perform their function. In neurons, microtubule organization—length, density, and dynamics—are essential for the establishment of polarity, growth, and transport. A mounting body
Ana Catarina Costa +2 more
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Frontiers in Molecular Neuroscience, 2018 In the adult nervous system axon caliber varies widely amongst different tracts. When considering a given axon, its diameter can further fluctuate in space and time, according to processes including the distribution of organelles and activity-dependent ...
Ana Rita Costa +4 more
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FEBS Open Bio, 2022 Spinal cord injury (SCI) often leads to sensory and motor dysfunction. Two major factors that hinder spinal cord repair are local inflammation and glial scar formation after SCI, and thus appropriate immunotherapy may alleviate damage.
Jianfeng Li +10 more
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Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation
Frontiers in Cell and Developmental Biology, 2021 Transthyretin (TTR), a plasma and cerebrospinal fluid protein, increases axon growth and organelle transport in sensory neurons. While neurons extend their axons, the microtubule (MT) cytoskeleton is crucial for the segregation of functional compartments
Jessica Eira +9 more
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Intradiscal injection for the management of low back pain
JOR Spine, 2022 Low back pain (LBP) is a common clinical problem and a major cause of physical disability, imposing a prominent socioeconomic burden. Intervertebral disc degeneration (IDD) has been considered the main cause of LBP.
Fu Zhang +5 more
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Effect of mechanical stimulation on tissue heterotopic ossification: an in vivo experimental study
Frontiers in Physiology, 2023 Background: Heterotopic ossification of tendons and ligaments (HOTL) is a common clinical condition characterized by the absence of discernible features and a lack of effective treatment. In vitro experiments have demonstrated that mechanical stimulation
Zhengya Zhu +18 more
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REGENERATION OF PERIPHERAL NERVES [PDF]
The Journal of Nervous and Mental Disease, 1916 n ...
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Neuroscience of Peripheral Nerve Regeneration
Journal of Pharmacy and Bioallied Sciences, 2021 Peripheral nerve injury involves complex molecular, cellular, and genetic events that help in ultimate regeneration of nerve. Some key factors are upregulated and some downregulated in the process of regeneration of nerve to attain almost perfect architecture.
Murugan Ramalingam, Sunil Paramel Mohan
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