Results 31 to 40 of about 1,438,567 (364)
Non-Muscle Myosin II in Axonal Cell Biology: From the Growth Cone to the Axon Initial Segment
Cells, 2020 By binding to actin filaments, non-muscle myosin II (NMII) generates actomyosin networks that hold unique contractile properties. Their dynamic nature is essential for neuronal biology including the establishment of polarity, growth cone formation and ...
Ana Rita Costa, Monica M. Sousa
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The Rate of Regeneration of Nerve [PDF]
Journal of Experimental Biology, 1942 ABSTRACT Five different methods have been used to estimate the rate of advance of regeneration along nerves in the rabbit. Not all give the same result. When the advance of the axon tips is studied a higher rate is recorded than when the times necessary for functional recovery are considered.
E. Gutmann +3 more
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Neurobiology of Disease, 2014 In Krabbe's disease (KD), a leukodystrophy caused by β-galactosylceramidase deficiency, demyelination and a myelin-independent axonopathy contributes to the severe neuropathology.
Carla Andreia Teixeira +8 more
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The Role of Spastin in Axon Biology
Frontiers in Cell and Developmental Biology, 2022 Neurons are highly polarized cells with elaborate shapes that allow them to perform their function. In neurons, microtubule organization—length, density, and dynamics—are essential for the establishment of polarity, growth, and transport. A mounting body
Ana Catarina Costa +2 more
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Optic Nerve Regeneration [PDF]
Archives of Ophthalmology, 2010 Retinal ganglion cells are usually not able to regenerate their axons after optic nerve injury or degenerative disorders, resulting in lifelong visual loss. This situation can be partially reversed by activating the intrinsic growth state of retinal ganglion cells, maintaining their viability, and counteracting inhibitory signals in the extracellular ...
Larry I. Benowitz, Yuqin Yin
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Frontiers in Molecular Neuroscience, 2018 In the adult nervous system axon caliber varies widely amongst different tracts. When considering a given axon, its diameter can further fluctuate in space and time, according to processes including the distribution of organelles and activity-dependent ...
Ana Rita Costa +4 more
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FEBS Open Bio, 2022 Spinal cord injury (SCI) often leads to sensory and motor dysfunction. Two major factors that hinder spinal cord repair are local inflammation and glial scar formation after SCI, and thus appropriate immunotherapy may alleviate damage.
Jianfeng Li +10 more
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Intradiscal injection for the management of low back pain
JOR Spine, 2022 Low back pain (LBP) is a common clinical problem and a major cause of physical disability, imposing a prominent socioeconomic burden. Intervertebral disc degeneration (IDD) has been considered the main cause of LBP.
Fu Zhang +5 more
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Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation
Frontiers in Cell and Developmental Biology, 2021 Transthyretin (TTR), a plasma and cerebrospinal fluid protein, increases axon growth and organelle transport in sensory neurons. While neurons extend their axons, the microtubule (MT) cytoskeleton is crucial for the segregation of functional compartments
Jessica Eira +9 more
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Nerve Regeneration and Nerve Suture [PDF]
The Journal of Nervous and Mental Disease, 1920 n ...
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