Results 11 to 20 of about 1,942,100 (397)

Light-Triggered Adhesive Silk-Based Film for Effective Photodynamic Antibacterial Therapy and Rapid Hemostasis

Frontiers in Bioengineering and Biotechnology, 2022
Successful control of massive hemorrhage in deep wounds with irregular shape and low elasticity still remains great challenges in the clinic. As the wound sites are usually at risk of bacterial infection, it is necessary to design an ideal hemostatic ...
Tingting Huang, Zhihao Zhou, Qiaoyuan Li, Xiaoxuan Tang, Xiaoxuan Tang, Xiaoli Chen, Yifan Ge, Jue Ling   +7 more
doaj   +1 more source

Immunoengineering nerve repair [PDF]

Proceedings of the National Academy of Sciences, 2017
SignificanceAnnually, more than 250,000 Americans suffer from a peripheral nerve injury, which results in a loss of function and a compromised quality of life. The current clinical gold standard to bridge long, nonhealing nerve gaps, the autograft, has several drawbacks.
Nassir Mokarram, Kyle Dymanus, Akhil Srinivasan, Johnathan G. Lyon, John Tipton, Jason Chu, Arthur W. English, Ravi V. Bellamkonda   +7 more
openaire   +2 more sources

Inhibition of Schwann cell pannexin 1 attenuates neuropathic pain through the suppression of inflammatory responses

Journal of Neuroinflammation, 2022
Background Neuropathic pain is still a challenge for clinical treatment as a result of the comprehensive pathogenesis. Although emerging evidence demonstrates the pivotal role of glial cells in regulating neuropathic pain, the role of Schwann cells and ...
Qian Wang, Han-yang Li, Zhuo-min Ling, Gang Chen, Zhong-Ya Wei   +4 more
doaj   +1 more source

Regenerative Role of T Cells in Nerve Repair and Functional Recovery

Frontiers in Immunology, 2022
The immune system is essential in the process of nerve repair after injury. Successful modulation of the immune response is regarded as an effective approach to improving treatment outcomes.
Xiaoxuan Tang, Xiaoxuan Tang, Qiaoyuan Li, Tingting Huang, Han Zhang, Xiaoli Chen, Jue Ling, Yumin Yang   +7 more
doaj   +1 more source

Visualizing peripheral nerve regeneration by whole mount staining. [PDF]

, 2015
Peripheral nerve trauma triggers a well characterised sequence of events both proximal and distal to the site of injury. Axons distal to the injury degenerate, Schwann cells convert to a repair supportive phenotype and macrophages enter the nerve to ...
A Erturk, A Hayashi, C Witzel, D Levy, D McDonald, D Triolo, David B. Parkinson, DP Yang, DW Zochodne, DW Zochodne, G Feng, G Stoll, H Hama, I Allodi, J Lau, JW Fawcett, LL Rong, ME Vargas, MW Klymkowsky, MW Painter, N Abe, N Kiguchi, PJ Arthur-Farraj, QT Nguyen, R Martini, S Chen, S Parrinello, Simone Di Giovanni, TM Brushart, W Bruck, Xin-peng Dun, YY Chen   +31 more
core   +16 more sources

Mechanisms of Schwann cell plasticity involved in peripheral nerve repair after injury

Cellular and Molecular Life Sciences, 2020
The great plasticity of Schwann cells (SCs), the myelinating glia of the peripheral nervous system (PNS), is a critical feature in the context of peripheral nerve regeneration following traumatic injuries and peripheral neuropathies. After a nerve damage,
Gianluigi Nocera, C. Jacob
semanticscholar   +1 more source

Peripheral nerve repair throughout the body with processed nerve allografts: Results from a large multicenter study

Microsurgery, 2020
Peripheral nerve damage resulting in pain, loss of sensation, or motor function may necessitate a reconstruction with a bridging material. The RANGER® Registry was designed to evaluate outcomes following nerve repair with processed nerve allograft ...
B. Safa, Sonu A Jain, Desai J Mihir, J. Greenberg, T. Niacaris, Jason A. Nydick, F. Leversedge, David M. Megee, J. Zoldos, B. Rinker, D. McKee, Brendan J Mackay, J. Ingari, L. Nesti, M. Cho, I. Valerio, Dennis S. Kao, Yasser El-Sheikh, Renata V. Weber, J. Shores, J. Styron, Wesley P. Thayer, Wojciech H. Przylecki, H. Hoyen, G. Buncke   +24 more
semanticscholar   +1 more source

The Effect of Schwann Cells/Schwann Cell-Like Cells on Cell Therapy for Peripheral Neuropathy

Frontiers in Cellular Neuroscience, 2022
Peripheral neuropathy is a common neurological issue that leads to sensory and motor disorders. Over time, the treatment for peripheral neuropathy has primarily focused on medications for specific symptoms and surgical techniques.
Qian Wang, Fang-Yu Chen, Zhuo-Min Ling, Wen-Feng Su, Ya-Yu Zhao, Gang Chen, Gang Chen, Gang Chen, Zhong-Ya Wei   +8 more
doaj   +1 more source

Isoquercitrin Delays Denervated Soleus Muscle Atrophy by Inhibiting Oxidative Stress and Inflammation

Frontiers in Physiology, 2020
Although denervated muscle atrophy is common, the underlying molecular mechanism remains unelucidated. We have previously found that oxidative stress and inflammatory response may be early events that trigger denervated muscle atrophy. Isoquercitrin is a
Yuntian Shen, Qiuyu Zhang, Ziwei Huang, Jianwei Zhu, Jiayi Qiu, Wenjing Ma, Xiaoming Yang, Fei Ding, Hualin Sun   +8 more
doaj   +1 more source

Comparative intra- and inter-observer reliability of two methods for evaluating intraoperative ultrasonography-based spinal cord hyperechogenicity intensity in degenerative cervical myelopathy

BMC Musculoskeletal Disorders, 2022
Objectives During French-door laminoplasty, a linear array transducer of IOUS was used to observe and record the spinal cord decompression. To acquire a higher-reliability method, and compare the in-observer and inter-observer reliability of two methods ...
Huachuan Wu, Guoliang Chen, Xianlong Li, Zhengya Zhu, Zuofeng Xu, Xizhe Liu, Shaoyu Liu   +6 more
doaj   +1 more source