Results 81 to 90 of about 1,694,794 (371)
Identification of Regulatory Factors and Prognostic Markers in Amyotrophic Lateral Sclerosis
Antioxidants, 2022 Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive degeneration of motor neurons, leading to muscle atrophy, paralysis and even death.
Hualin Sun +10 more
doaj +1 more source
Photoacoustic Silk Scaffolds for Neural stimulation and Regeneration [PDF]
arXiv, 2021 Neural interfaces using biocompatible scaffolds provide crucial properties for the functional repair of nerve injuries and neurodegenerative diseases, including cell adhesion, structural support, and mass transport. Neural stimulation has also been found to be effective in promoting neural regeneration.
arxiv
FEBS Open Bio, EarlyView.Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei +7 more
wiley +1 more source
Recovery of Motor Function after Mixed and Motor Nerve Repair with Processed Nerve Allograft
Plastic and Reconstructive Surgery, Global Open, 2019 Background: Severe trauma often results in the transection of major peripheral nerves. The RANGER Registry is an ongoing observational study on the use and outcomes of processed nerve allografts (PNAs; Avance Nerve Graft, AxoGen, Inc., Alachua, Fla ...
B. Safa +9 more
semanticscholar +1 more source
Automatic Ultrasound Image Segmentation of Supraclavicular Nerve Using Dilated U-Net Deep Learning Architecture [PDF]
arXiv, 2022 Automated object recognition in medical images can facilitate medical diagnosis and treatment. In this paper, we automatically segmented supraclavicular nerves in ultrasound images to assist in injecting peripheral nerve blocks. Nerve blocks are generally used for pain treatment after surgery, where ultrasound guidance is used to inject local ...
arxiv
Nerve Repair with Nerve Conduits: Problems, Solutions, and Future Directions
Journal of hand and microsurgery, 2018 Nerve conduits are becoming increasingly popular for the repair of peripheral nerve injuries. Their ease of application and lack of donor site morbidity make them an attractive option for nerve repair in many situations.
Ryan E. Rebowe +5 more
semanticscholar +1 more source
Frontiers in Physiology, 2022 Peripheral nerve injury is common, and can lead to skeletal muscle atrophy and dysfunction. However, the underlying molecular mechanisms are not fully understood. The transcription factors have been proved to play a key role in denervated muscle atrophy.
Xiaoming Yang +11 more
doaj +1 more source
Recent advances in nerve repair
Neurology India, 2019 Peripheral nerve injuries are extremely devastating, and their management is exceedingly complex. Microsurgical repair is the mainstay of treatment and this includes direct nerve repair, nerve grafts, nerve tubes and nerve transfers.
Sudheesh Ramachandran, R. Midha
semanticscholar +1 more source
Frontiers in Physiology, 2019 Denervation induces skeletal muscle atrophy, accompanied by complex biochemical and physiological changes, with potentially devastating outcomes even an increased mortality.
Yuntian Shen +10 more
doaj +1 more source
Bioadhesive Graft-Antenna for Stimulation and Repair of Peripheral Nerves [PDF]
arXiv, 2018 Peripheral nerve injuries are difficult to treat due to limited axon regeneration; brief electrical stimulation of injured nerves is an emerging therapy that can relieve pain and enhance regeneration. We report an original wireless stimulator based on a metal loop (diameter ~1 mm) that is powered by a transcranial magnetic stimulator (TMS).
arxiv