Results 41 to 50 of about 2,564,504 (355)

CNV and nervous system diseases - what's new? [PDF]

open access: yes, 2008
Several new genomic disorders caused by copy number variation (CNV) of genes whose dosage is critical for the physiological function of the nervous system have been recently identified.
Gu, W., Lupski, J. R.
core   +3 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Stepwise-targeting and hypoxia-responsive liposome AMVY@NPs carrying siYAP and verteporfin for glioblastoma therapy

open access: yesJournal of Nanobiotechnology
Background The Hippo pathway is a conserved tumour suppressor signalling pathway, and its dysregulation is often associated with abnormal cell growth and tumorigenesis.
Ji Qi   +11 more
doaj   +1 more source

Time Series Analysis using Embedding Dimension on Heart Rate Variability [PDF]

open access: yes, 2018
Heart Rate Variability (HRV) is the measurement sequence with one or more visible variables of an underlying dynamic system, whose state changes with time. In practice, it is difficult to know what variables determine the actual dynamic system.
Abarbanel   +14 more
core   +2 more sources

Immunophilins in the Nervous System [PDF]

open access: yesNeuron, 1998
Supported by United States Public Health Service grant MH-18501, Research Scientist Award DA-00074 to S. H. S., and Training Grant GM-07309 to M. M. L. and P. E. B. S. H. S. owns stock in and is entitled to royalties from Guilford Pharmaceuticals, which is developing products related to immunophilins.
Michael M. Lai   +2 more
openaire   +3 more sources

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Observation of experimental lathyrism in the rat [PDF]

open access: yes, 1959
The clinical manifestations, roentgenologic studies, and histopathologic findings of the central nervous system of rats with induced lathyrism were described.
Lee, HUN Jae
core   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

The enteric nervous system [PDF]

open access: yesDevelopmental Biology, 2012
The enteric nervous system (ENS), the intrinsic innervation of the gastrointestinal tract, consists of numerous types of neurons, and glial cells, that are distributed in two intramuscular plexuses that extend along the entire length of the gut and control co-ordinated smooth muscle contractile activity and other gut functions.
Vassilis Pachnis   +2 more
openaire   +2 more sources

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