Results 81 to 90 of about 3,155,450 (380)

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

open access: yesFEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal   +2 more
wiley   +1 more source

Impact of coadministration of apigenin and bone marrow stromal cells on damaged ovaries due to chemotherapy in rat: An experimental study

open access: yesInternational Journal of Reproductive BioMedicine, 2020
Background: Apigenin is a plant-derived flavonoid with antioxidative and antiapoptotic effects. Bone marrow stromal cells (BMSCs) are a type of mesenchymal stem cells (MSCs) that may recover damaged ovaries.
Athar Talebi   +3 more
doaj   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

open access: yesFEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji   +3 more
wiley   +1 more source

Cognitive impairments in patients with prior ischemic stroke

open access: yesНеврология, нейропсихиатрия, психосоматика, 2014
The authors give the data available in the literature on and the results of their studies of the epidemiology, risk factors, pathogenesis, diagnosis, and treatment of poststroke cognitive impairment (PSCI).
V. A. Parfenov   +4 more
doaj   +1 more source

Comprehensive profiling of stem-like features in pediatric glioma cell cultures and their relation to the subventricular zone

open access: yesActa Neuropathologica Communications, 2023
Pediatric high-grade gliomas (pHGG) are brain tumors occurring in children and adolescents associated with a dismal prognosis despite existing treatments. Therapeutic failure in both adult and pHGG has been partially imputed to glioma stem cells (GSC), a
Marc-Antoine Da-Veiga   +5 more
doaj   +1 more source

Virtual Nervous Systems for Self-Assembling Robots - A preliminary report [PDF]

open access: yesarXiv, 2015
We define the nervous system of a robot as the processing unit responsible for controlling the robot body, together with the links between the processing unit and the sensorimotor hardware of the robot - i.e., the equivalent of the central nervous system in biological organisms.
arxiv  

Old equations for a new system: A possible use of Navier-Stokes equations to model the circulation of spikes in the nervous system [PDF]

open access: yesarXiv, 2011
In the present work we discuss a possible application of Navier-Stokes-based models to the quantitative description of the circulation of nervous impulses throughout the nervous system. In previous works we have shown that the discharge from Basal Ganglia neurons from patients with Parkinson's disease share mathematical features with the velocity ...
arxiv  

Outreach Education: Making Neuroscience Readily Available for Rural Students and Communities of Alaska [PDF]

open access: yes, 2013
WHAT is neuroscience? Neuroscience is the scientific study of the structure or function of the nervous system and brain. To get a grasp on the vast study of neuroscience, first think of the human body and how complex it is. Think of the skeletal system
Ellison, Ariel
core  

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

open access: yesAging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Diagnosis of Alzheimer's disease by using biological markers in posterior cortical atrophy

open access: yesНеврология, нейропсихиатрия, психосоматика
The use of biological markers for Alzheimer's disease (AD) allows diagnosis at the stage of moderate cognitive impairment and atypical course of the disease.
D. A. Grishina   +3 more
doaj   +1 more source

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